ophthalmologyОфтальмологияOphthalmology in Russia1816-50952500-0845Ophthalmology10.18008/1816-5095-2019-4-479-486ophthalmology-1081Research ArticleКЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯCLINICAL & EXPERIMENTAL RESEARCHМитохондриальная ДНК как фактор развития глаукомной оптической нейропатииMitochondrial DNA as a Factor of Glaucomous Optic Neuropathy’s Development MechanismГазизоваИ. Р.GazizovaI. R.

доктор медицинских наук, врач‑офтальмолог

ул. Академика Павлова, 12, Санкт‑Петербург, 197376, Российская Федерация

MD, ophtalmologist

Akademika Pavlova str., 12, Saint Petersburg, 197376, Russian Federation

ilmiraufa88@gmail.comМазунинИ. О.MazuninI. O.

кандидат медицинских наук, заведующий лабораторией молекулярно‑генетических технологий

ул. А. Невского, 14, Калининград, 236016, Российская Федерация

PhD, head of laboratory of molecular genetic technologies

A. Nevskogo str., 14, Kaliningrad, 236016, Russian Federation

МалишевскаяТ. Н.MalishevskayaT. N.

доктор медицинских наук, руководитель отделения аналитической работы

ул. Садовая‑Черногрязская, 14/19, Москва, 105062, Российская Федерация

MD, ophtalmologist, Head of Analytical Work

Sadovaya‑Chernogryazskaya str., 14/19, Moscow, 105062, Russian Federation

КиселеваО. А.KiselevaO. A.

доктор медицинских наук, начальник отдела глаукомы

ул. Садовая‑Черногрязская, 14/19, Москва, 105062, Российская Федерация

MD, Head of Glaucoma Department

Sadovaya‑Chernogryazskaya str., 14/19, Moscow, 105062, Russian Federation

ГаджиевА. М.GadzhievA. M.

врач‑офтальмолог

Колтушское шоссе, 20, Всеволожск, 188640, Российская Федерация

Ophtalmologist

Koltushskoe highway, 20, Vsevolozhsk, 188640, Russian Federation

РинджибалАл.-М.RindzhibalAl.-M.

аспирант

ул. Академика Павлова, 12, Санкт‑Петербург, 197376, Российская Федерация

рostgraduate

Akademika Pavlova str., 12, Saint Petersburg, 197376, Russian Federation

ФГБНУ «Институт экспериментальной медицины»РоссияInstitute of Experimental MedicineRussian FederationЦентр геномных исследований, Балтийский федеральный университет им. И. КантаРоссияCenter for Genomic Research, Immanuel Kant Baltic Federal UniversityRussian FederationНациональный медицинский исследовательский центр глазных болезней им. ГельмгольцаРоссияHelmholtz National medical center of Eye DiseasesRussian FederationГБУЗ Ленинградской области «Всеволожская клиническая межрайонная больница»РоссияState instituition of health care of Leningrad region “Vsevolozhsk clinical interdistrict hospital”Russian Federation201925122019164479486Copyright © Газизова И.Р., Мазунин И.О., Малишевская Т.Н., Киселева О.А., Гаджиев А.М., Ринджибал А., 20192019Газизова И.Р., Мазунин И.О., Малишевская Т.Н., Киселева О.А., Гаджиев А.М., Ринджибал А.Gazizova I.R., Mazunin I.O., Malishevskaya T.N., Kiseleva O.A., Gadzhiev A.M., Rindzhibal A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ophthalmojournal.com/opht/article/view/1081глаукомная оптическая нейропатияпервичная открытоугольная глаукомамитохондриальная дисфункциямитохондриальная генетикамитохондриальная ДНК (мтДНК)митохондриальные гаплогруппыкоррекция мутаций мтДНКмитохондриальный окислительный стрессglaucoma optic neuropathyprimary open-angle glaucomamitochondrial dysfunctionmitochondrial geneticsmitochondrial DNA (mtDNA)mitochondrial haplogroupsmtDNA mutations correctionmitochondrial oxidative stressReferencesQuigley H.A., Broman A.T. 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The authors declare that there are no conflicts of interest present.