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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2020-1-5-12</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-1125</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Диагностические возможности оптической когерентной томографии сетчатки при компрессии в хиазмально-селлярной области</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic Possibilities of Optical Coherent Tomography of the Retina during Compression in the Chiasm-Sellar Region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврилова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаврилова Наталья Александровна доктор медицинских наук, профессор, зав. кафедрой глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127486</p></bio><bio xml:lang="en"><p>Gavrilova Natalia A. MD, PhD, professor</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иойлева</surname><given-names>Е. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Ioyleva</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иойлева Елена Эдуардовна доктор медицинских наук, ученый секретарь ФГАУ МНТК “Микрохирургия гла‑ за” им. акад. С.Н. Федорова; профессор кафедры глазных болезней</p><p>Бескудниковский бульвар, 59 А, Москва, 127486  ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Ioyleva Elena E. MD, PhD, professor</p><p>Beskudnikovsky blvd, 59a, Moscow, 127486 Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаджиева</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gadzhieva</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаджиева Нурия Саниевна кандидат медицинских наук, доцент кафедры глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Gadzhieva Nuria S. MD, assistant professor</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тищенко</surname><given-names>О. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tishchenko</surname><given-names>O. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тищенко Ольга Евгеньевна кандидат медицинских наук, доцент кафедры глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Tishchenko Ol’ga E. MD, assistant professor</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутровская</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutrovskaya</surname><given-names>N. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутровская Наталья Юрьевна кандидат медицинских наук, ассистент кафедры глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Kutrovskaya Natalia Y. MD, assistant</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuz’mina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузьмина Анастасия Владимировна аспирант кафедры глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Kuz’mina Anastasiya V. postgraduate</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиновьева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinov’eva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зиновьева Александра Витальевна ординатор кафедры глазных болезней</p><p>ул. Делегатская, 20, стр. 1, Москва, 127473</p></bio><bio xml:lang="en"><p>Zinov’eva Aleksandra V. resident</p><p>Delegatskaya str., 20, p. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Министерства здравоохранения Российской Федерации;&#13;
ФГАУ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The S. Fyodorov Eye Microsurgery Federal State Institution&#13;
A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2020</year></pub-date><volume>17</volume><issue>1</issue><fpage>5</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаврилова Н.А., Иойлева Е.Э., Гаджиева Н.С., Тищенко О.Е., Кутровская Н.Ю., Кузьмина А.В., Зиновьева А.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Гаврилова Н.А., Иойлева Е.Э., Гаджиева Н.С., Тищенко О.Е., Кутровская Н.Ю., Кузьмина А.В., Зиновьева А.В.</copyright-holder><copyright-holder xml:lang="en">Gavrilova N.A., Ioyleva E.E., Gadzhieva N.S., Tishchenko O.E., Kutrovskaya N.Y., Kuz’mina A.V., Zinov’eva A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/1125">https://www.ophthalmojournal.com/opht/article/view/1125</self-uri><abstract><p>Сохранение и восстановление зрительных функций при компрессии в хиазмально-селлярной области возможно в случае раннего диагностирования патологии и своевременного проведения хирургической декомпрессии. Оптическая когерентная томография (ОСТ) сетчатки в настоящее время является одним из наиболее информативных методов диагностики патологии сетчатки и зрительного нерва и может позволить, благодаря наличию ранних диагностических критериев, своевременно выявлять наличие компрессии в хиазмально-селлярной области и расширять показания для проведения хирургического лечения. В связи с этим в литературном обзоре представлены результаты проведения оптической когерентной томографии (ОСТ) сетчатки при компрессии в хиазмально-селлярной области. В результате анализа литературных данных выявлено, что при хиазмальной компрессии наблюдается снижение показателей толщины слоя нервных волокон в перипапиллярной и макулярной области и снижение показателя толщины макулярного комплекса, состоящего из слоя ганглиозных клеток сетчатки и внутреннего плексиформного слоя. Установлено, что снижение показателя толщины макулярного комплекса при хиазмальной компрессии в ряде случаев предшествует изменениям в поле зрения. По результатам единичных исследований между показателями толщины перипапиллярного RNFL и плотности внутреннего капиллярного сплетения сетчатки в тех же областях выявлено наличие корреляционной зависимости. Результаты анализа литературных источников разных авторов резюмированы в таблице по исследуемым параметрам, модели OCT; этиологии, методам лечения заболевания и результатам исследования OCT. Несмотря на полученные результаты, ранние специфические и чувствительные ОСТ-диагностические критерии хиазмальной компрессии в настоящее время не разработаны. Кроме того, изменение толщины GCC и RNFL может наблюдаться и при отсутствии хиазмальной компрессии при определенных типах опухолей и наличии сопутствующей патологии (артериальная гипертензия). В связи с этим необходимо проведение дальнейших исследований, которые позволят не только выявлять информативные ОСТ-диагностические критерии компрессии в хиазмально-селлярной области, но и разрабатывать диагностические алгоритмы с учетом типа опухоли, наличия сопутствующей патологии и т.д. Ранние диагностические критерии хиазмальной компрессии позволят расширить показания и повысить результат хирургического лечения пациентов и сохранить зрительные функции.</p></abstract><trans-abstract xml:lang="en"><p>Recovery and preservation of visual functions during compression in the chiasm-sellar region is possible in the case of early diagnosis of pathology and timely surgical decompression. Today optical coherence tomography (OCT) of the retina is one of the most informative methods for diagnosing pathology of the retina and optic nerve. It can, due to the presence of early diagnostic criteria, promptly detect the compression in the chiasm-sellar region and expand the indications for surgical treatment. The literature review presents the results of optical coherent tomography (OCT) of the retina during compression in the chiasm-sellar region. An analysis of literature data revealed that in patients with chiasmatic compression, the thickness of the nerve fiber layer in the peripapillary and macular areas decreases, the thickness of the macular complex, consisting of the retinal ganglion cell layer and the inner plexiform layer, decreases. Also, there is a change in the value of asymmetry between the GCC thickness indices in the nasal and temporal halves of the macular region. It has been established that a decrease in the thickness index of a macular complex may precede changes in the visual field. According to the results of single studies, a correlation was found between the parameters of the peripapillary RNFL thickness and the the internal capillary retinal plexus density in the same areas. The results of literature sources’s analysis are summarized in the table by the parameters studied, the OCT model; etiology, treating methods and the results of the OCT study. Despite the results obtained, the early specific and sensitive OCT diagnostic criteria for chiasmatic compression have not yet been developed. In addition, a change in the thickness of GCC and RNFL can also be observed in the absence of chiasmatic compression in certain types of tumors and in the presence of comorbidities (arterial hypertension). In this regard, it is necessary to conduct further studies that will reveal the informative OСT-diagnostic criteria for compression in the chiasm-sellar region, develop diagnostic algorithms taking into account the type of tumor, the presence of concomitant pathology. Early diagnostic criteria for chiasmatic compression will expand the indications and improve the result of surgical treatment of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>компрессия хиазмально-селлярной области</kwd><kwd>оптическая когерентная томография</kwd><kwd>ОСТ-ангиография</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>compression of the chiasm-sellar region</kwd><kwd>optical coherence tomography</kwd><kwd>OСT-angiography</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Leal B.C., Moura F.C., Monteiro M.L. Retinal nerve fiber layer loss documented by Stratus OCT in patients with pituitary adenoma: case report. Arq Bras Oftalmol. 2006;69(2):251–254. DOI: 10.1590/S0004-27492006000200021</mixed-citation><mixed-citation xml:lang="en">Leal B.C., Moura F.C., Monteiro M.L. 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