ophthalmologyОфтальмологияOphthalmology in Russia1816-50952500-0845Ophthalmology10.18008/1816-5095-2020-3-344-350ophthalmology-1273Research ArticleОБЗОРЫREVIEWSИзменения глазной поверхности после кераторефракционных вмешательств. Обзор литературыChanges the Ocular Surface after Corneal Refractive Surgery. Reviewhttps://orcid.org/0000-0003-4360-793XТруфановС. В.TrufanovS. V.

доктор медицинских наук, ведущий научный сотрудник отдела патологии роговицы,

ул. Россолимо, 11а, б, Москва, 119021

MD, leading research associate,

Rossolimo str., 11A, B, Moscow, 119021

СухановаЕ. В.SukhanovaE. V.

кандидат медицинских наук, научный сотрудник отдела рефракционных нарушений,

ул. Россолимо, 11а, б, Москва, 119021

PhD, ophthalmologist of the refractive errors department,

Rossolimo str., 11A, B, Moscow, 119021

elenasukhanova@mail.ruhttps://orcid.org/0000-0002-2210-130XТюринаА. А.TyurinaA. A.

аспирант, отдел рефракционных нарушений,

ул. Россолимо, 11а, б, Москва, 119021

postgraduate of the refractive errors department,

Rossolimo str., 11A, B, Moscow, 119021

ФГБНУ «Научно-исследовательский институт глазных болезней»РоссияResearch Institute of Eye DiseasesRussian Federation202022092020173344350Copyright © Труфанов С.В., Суханова Е.В., Тюрина А.А., 20202020Труфанов С.В., Суханова Е.В., Тюрина А.А.Trufanov S.V., Sukhanova E.V., Tyurina A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ophthalmojournal.com/opht/article/view/1273

Современная кераторефракционная хирургия обеспечивает высокую эффективность, безопасность, предсказуемость, стабильность клинико-функциональных результатов коррекции различных видов аметропий. Однако в подавляющем проценте случаев в различные сроки после операции пациенты предъявляют жалобы на дискомфорт, сухость в глазах, жжение, чувство инородного тела, покраснение, затуманивание и нестабильность зрения. Вышеперечисленные жалобы обусловлены появлением транзиторного синдрома сухого глаза (ССГ). В обзоре представлены основные факторы этиологии и патогенеза данного заболевания. Проанализированы результаты «классических» методов диагностики ССГ, а также современных методик, отличающихся высокой специфичностью и чувствительностью, что позволяет повысить точность диагностики ССГ. Изучению ССГ после кераторефракционных операций (КРО) посвящено огромное число работ отечественных и зарубежных авторов. Однако в настоящее время нет единого алгоритма оценки поражения глазной поверхности до и после КРО, которая включала бы набор высокоточных и специфичных методик, позволяющих быстро и достоверно оценивать степень тяжести ССГ, что позволит выработать меры профилактики и патогенетически ориентированного лечения и тем самым ускорить реабилитацию пациентов после операции. Необходимо продолжение исследований в данном направлении.

Modern corneal refractive surgery provides high efficiency, safety, predictability and stability of the different ametropia kinds correction’s clinically-functional results. However, in overwhelming percentage of cases, having spent some time after surgery patients complain about discomfort, eyes dryness, burning, feel gritty, redness, blurred and vision instability. Complaints mentioned above are caused by the appearance of transitory dry eye syndrome. Main etiology and pathogenesis factors of this disease are presented in this review. The results of dry eye syndrome classical diagnosis methods have been analyzed, as well as modern techniques, characterized by high specificity and sensitivity, which allow to increase the dry eye’s diagnostics accuracy. The study of the dry syndrome after corneal refractive surgery is devoted to a huge number of works of domestic and foreign authors. However, at present time there is no unique algorithm for assessing the damage of the ocular surface before and after corneal refractive surgery, which would include a set of high-precision and specific techniques for quickly and reliably evaluate the severity of dry eye syndrome, allowing to develop preventive measures and pathogenetically oriented treatment and, thereby, accelerate rehabilitation of patients after surgery. Research continuation is needed in this direction.

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The authors declare that there are no conflicts of interest present.