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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2022-1-33-37</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-1767</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Контракционный капсулярный синдром. Обзор. Часть 1</article-title><trans-title-group xml:lang="en"><trans-title>Capsular Contraction Syndrome. Review. Part 1</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванов Дмитрий Иванович, доктор медицинских наук, заведующий II хирургическим отделением, врач-офтальмохирург</p><p>ул. Академика Бардина, 4а, Екатеринбург, 620149</p></bio><bio xml:lang="en"><p>Ivanov Dmitry I., MD, Head of II Surgical Department, Ophthalmosurgeon</p><p>A. Bardina str.,. 4A, Ekaterinburg, 620149</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитин Владимир Николаевич, врач-офтальмохирург II хирургического отделения</p><p>ул. Академика Бардина, 4а, Екатеринбург, 620149</p></bio><bio xml:lang="en"><p>Nikitin Vladimir N., Ophthalmosurgeon of II Surgical Department</p><p>A. Bardina str.,. 4A, Ekaterinburg, 620149</p></bio><email xlink:type="simple">Wladimir.dok@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>АО «Екатеринбургский центр МНТК “Микрохирургия глaзa” им. академика С.Н. Федорова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Eye Microsurgery Ekaterinburg Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>06</day><month>04</month><year>2022</year></pub-date><volume>19</volume><issue>1</issue><fpage>33</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванов Д.И., Никитин В.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Иванов Д.И., Никитин В.Н.</copyright-holder><copyright-holder xml:lang="en">Ivanov D.I., Nikitin V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/1767">https://www.ophthalmojournal.com/opht/article/view/1767</self-uri><abstract><p>Прогрессирующий рост количества факоэмульсификаций в мире приводит к пропорциональному увеличению фиброзных изменений капсульного мешка в послеоперационном периоде, которые возникают даже в неосложненных случаях. Структурные изменения капсулы хрусталика вызывают развитие контракционного капсулярного синдрома (КСС), который встречается с частотой до 58,5 % в различные сроки после операции. Клинические проявления КСС могут быть разнообразны: от бессимптомного течения до серьезных функциональных и анатомических нарушений. В статье представлена обобщающая информация о предрасполагающих факторах, условиях и причинах возникновения КСС. Рассмотрена последовательность изменений хрусталиковых клеток, называемая эпителиально-мезенхимальной трансформацией, являющейся основой патогенеза ККС. Объяснены механизмы влияния материала и конструкции ИОЛ, размера и формы переднего капсулорексиса на развитие патологического процесса.</p></abstract><trans-abstract xml:lang="en"><p>The progressive increase of the number of phacoemulsification in the world leads to a proportional increase in the number of fibrous changes of the capsular bag in the postoperative period. Changes of the capsular bag occur even in simple cases. Structural changes in the lens capsule cause the development of contractional capsular syndrome. It occurs in up to 58.5 % of cases at various times after surgery. Clinical manifestations of contractional syndrome can be diverse: from an asymptomatic course to serious functional and anatomical disorders. The article provides general information about predisposing factors, conditions and causes of capsular syndrome. The paper considers the sequence of changes in the lens cells named epithelial-mesenchymal transformation. Transformation is the basis of the capsular syndrome pathogenesis. The article reveals the mechanisms of influence of the material and design of the IOL, size and shape of anterior rhexis on the development of the pathological process.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>контракционный капсулярный синдром</kwd><kwd>фиброз капсулы хрусталика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>capsular contraction syndrome</kwd><kwd>lens fibrosis capsules</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brian G., Taylor H. Cataract blindness: challenges for the 21st century. Bulletin of the World Health Organization. 2001;79:249–256.</mixed-citation><mixed-citation xml:lang="en">Brian G., Taylor H. Cataract blindness: challenges for the 21st century. 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