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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2022-3-515-523</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-1915</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOSURGERY</subject></subj-group></article-categories><title-group><article-title>Преимущества технологии Micropulse как метода выбора лечения вторичной глаукомы у пациентов с заболеваниями роговицы</article-title><trans-title-group xml:lang="en"><trans-title>Advantages of Micropulse Technology as a Method of Choice for the Treatment of Secondary Glaucoma in Patients with Corneal Diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сидорова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sidorova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог высшей категории, заведующая отделением хирургического лечения глаукомы,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>ophthalmologist of the highest category, head of the Glaucoma surgical treatment department,</p><p>Beskudnikovsky blvd, 59A, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старостина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Starostina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач-офтальмолог, научный сотрудник отделения хирургического лечения глаукомы,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>PhD, ophthalmologist, researcher of the Glaucoma surgical treatment department,</p><p>Beskudnikovsky blvd, 59A, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Печерская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pecherskaia</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог, аспирант,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>ophthalmologist, postgraduate,</p><p>Beskudnikovsky blvd, 59A, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стефанкова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stefankova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>ophthalmologist,</p><p>Beskudnikovsky blvd, 59A, Moscow, 127486</p></bio><email xlink:type="simple">kstiefankova@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.N. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2022</year></pub-date><volume>19</volume><issue>3</issue><fpage>515</fpage><lpage>523</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сидорова А.В., Старостина А.В., Печерская М.А., Стефанкова К.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Сидорова А.В., Старостина А.В., Печерская М.А., Стефанкова К.А.</copyright-holder><copyright-holder xml:lang="en">Sidorova A.V., Starostina A.V., Pecherskaia M.A., Stefankova K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/1915">https://www.ophthalmojournal.com/opht/article/view/1915</self-uri><abstract><p>Посткератопластическая глаукома развивается после пересадки роговицы в среднем в 10–53 % случаев. Для стабилизации офтальмотонуса у таких пациентов было предложено использовать микроимпульсную лазерную хирургию.</p><sec><title>Цель</title><p>Цель: оценить эффективность проведения микроимпульсной лазерной хирургии у пациентов с вторичной рефрактерной глаукомой после кератопластики.</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. В исследование были включены 27 глаз после различных видов кератопластики. Средний уровень внутриглазного давления составлял 33,2 ± 3,7 мм рт. ст., среднее количество гипотензивных капель — 2,9 ± 0,7. Острота зрения варьировала от неправильной светопроекции до 0,3 с коррекцией. Микроимпульсное лазерное лечение было проведено со стандартными настройками прибора и мощностью 2800 мВт.</p></sec><sec><title>Результаты</title><p>Результаты. На первые сутки после операции у 24 пациентов было отмечено снижение ВГД в среднем на 24 % от исходного уровня и составило 25,6 ± 3,3 мм рт. ст. У 3 пациентов был отмечен реактивный подъем ВГД в среднем на 5 % — 33–36 мм рт. ст. Через 12 месяцев наблюдения средний уровень ВГД составил 24,9 ± 1,8 мм рт. ст. на гипотензивном режиме, отмечено снижение на 24,5 %, количество гипотензивных капель было уменьшено до 2,1 ± 0,7. В 6 случаях диагностировано повышение остроты зрения на 1–2 строчки в связи с уменьшением отека роговицы. В 3 случаях через 1–2 месяца после лазерной хирургии пациентам была выполнена повторная пересадка десцеметовой мембраны. Однако у 2 пациентов было отмечено повторное повышение ВГД до 27–30 мм рт. ст., было принято решение о проведении повторной операции с мощностью 2800 мВт. При наблюдении до 3 месяцев ВГД соответствовало целевому уровню и в среднем составляло 18–20 мм рт. ст. При помощи ультразвуковой биомикроскопии у всех пациентов отслеживалась динамика изменения толщины цилиарного тела. Средняя толщина до операции составляла 0,56 ± 0,11 мм. Через 12 месяцев статистической разницы с дооперационными значениями не отмечено, средние значения составляли 0,55 ± 0,10 мм, отмечалась сохранность всех его основных структур.</p></sec><sec><title>Заключение</title><p>Заключение. Микроимпульсная циклофотокоагуляция является эффективным и безопасным методом лечения вторичной рефрактерной глаукомы на глазах как до кератопластики, так и после повторной пересадки, что открывает новые перспективы в лечении глаукомы, сочетанной с заболеваниями роговицы. </p></sec></abstract><trans-abstract xml:lang="en"><p>Postkeratoplasty glaucoma develops after cornea transplantation in 10–53 % cases. For ophthalmotonus stabilization in patients, it was proposed to use micropulse laser surgery.</p><sec><title>Purpose</title><p>Purpose. To evaluate the effectiveness of micropulse laser surgery in patients with secondary refractory glaucoma after keratoplasty.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. The study included 27 eyes after different types of keratoplasty. The average level of intraocular pressure was 33.2 ± 3.7 mmHg, the average number of hypotensive drops was 2.9 ± 0.7. Visual acuity varied from incorrect light perception to 0.3 with correction. Micropulse laser treatment was performed with the standard settings and a power of 2800 mW.</p></sec><sec><title>Results</title><p>Results. On the first day after laser surgery, 24 patients had a decrease in IOP by an average of 24 % to 25.6 ± 3.3 mmHg. Three patients had a reactive increase in IOP by an average of 5 % to 33–36 mmHg. After 12 months of follow-up, the average IOP level was 24.9 ± 1.8 on the hypotensive drops, a decrease of IOP was 24.5 %, the number of hypotensive drops was reduced to 2.1 ± 0.7. In 6 cases, an increase in visual acuity by 1–2 lines was diagnosed due to a decrease in corneal edema. In 3 cases, 1–2 months after laser surgery, patients underwent second transplantation of the Descemet membrane. However, in 2 patients, an IOP increased again to 27–30 mmHg, and it was decided to conduct a repeated micropulse surgery with a power of 2800 mW. When observed for up to 3 months, IOP respond to the target level and averaged 18-20 mmHg. Using ultrasound biomicroscopy, the dynamics of changes in the thickness of the ciliary body was followed in all patients, the average thickness before surgery was 0.56 ± 0.11 mm. After 12 months, there was no statistical difference with the preoperative thickness, the average values were 0.55 ± 0.10 mm, the safety of its main structures was noted.</p></sec><sec><title>Conclusion</title><p>Conclusion. Micropulse cyclophotocoagulation is an effective and safe method of treating secondary refractory glaucoma in the eyes both before keratoplasty and after repeated cornea transplantation, which opens up new prospects in the treatment of glaucoma combined with corneal diseases. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>посткератопластическая глаукома</kwd><kwd>рефрактерная глаукома</kwd><kwd>мироимпульсная циклофотокоагуляция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postkeratoplasty glaucoma</kwd><kwd>refractory glaucoma</kwd><kwd>micropulse cyclophotocoagulation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Егоров Е.А. Национальное руководство по глаукоме. 3-е изд. М.: ГЭОТАРМедиа, 2013. С. 44–62.</mixed-citation><mixed-citation xml:lang="en">Egorov E.A. National guide to glaucoma. 3rd ed. Moscow: GEOTAR-Media, 2013. 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