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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2022-3-617-623</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-1930</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL &amp; EXPERIMENTAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Латеральные фенотипы у детей с офтальмопатологией</article-title><trans-title-group xml:lang="en"><trans-title>Lateral Phenotypes in Children with Ophthalmopathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рычкова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Rychkova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач-офтальмолог, ведущий научный сотрудник лаборатории «Зрительные системы»,</p><p>Большой Каретный переулок, 19, Москва, 127051</p></bio><bio xml:lang="en"><p>PhD, оphthalmologist, leading researcher of the laboratory of the “Visual system”,</p><p>Bolshoy Karetny lane, 19, Moscow, 127051</p></bio><email xlink:type="simple">lana.rych@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лихванцева</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Likhvantseva</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, ул. Гамалеи, 15, Москва, 123098;</p><p>профессор кафедры офтальмологии, Волоколамское шоссе, 91, Москва, 125310</p></bio><bio xml:lang="en"><p>MD, Professor of the Department of ophthalmology,</p><p>Gamalei str., 15, Moscow, 123098;</p><p>Volokolamskoe highway, 91, Moscow, 125371</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сандимиров</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sandimirov</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент,</p><p>ул. Островитянова, 1, Москва, 117997</p></bio><bio xml:lang="en"><p>student,</p><p>Ostrovityanova str., 1 Moscow, 117997</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУН «Институт проблем передачи информации им. А.А. Харкевича» Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kharkevich Institute for Information Transmission Problems of RAS</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Государственный научный центр «Федеральный медицинский биофизический центр имени А.И. Бурназяна» Федерального медико-биологического агентства;&#13;
ФПК «Академия постдипломного образования» ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий» Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Burnazyan Federal Biophysical Center of Federal Medical-Biological Agency;&#13;
Academy of Postgraduate Education of Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of Federal Medical-Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>07</day><month>10</month><year>2022</year></pub-date><volume>19</volume><issue>3</issue><fpage>617</fpage><lpage>623</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рычкова С.И., Лихванцева В.Г., Сандимиров Р.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Рычкова С.И., Лихванцева В.Г., Сандимиров Р.И.</copyright-holder><copyright-holder xml:lang="en">Rychkova S.I., Likhvantseva V.G., Sandimirov R.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/1930">https://www.ophthalmojournal.com/opht/article/view/1930</self-uri><abstract><p>Работа посвящена одной из актуальных проблем офтальмологии и нейрофизиологии — исследованию межполушарных взаимодействий у детей в норме и при офтальмопатологии.</p><p>Цель работы — исследование латеральных фенотипов у детей с офтальмопатологией.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Под наблюдением находились 374 ребенка в возрасте 6–15 лет: 1) 160 детей с содружественным косоглазием; 2) 111 детей с органической патологией сетчатки и зрительного нерва; 3) 103 ребенка контрольной группы (без офтальмопатологии). Латеральный фенотип (ЛФ) определяли по схеме «ведущая рука — доминирующее ухо — доминирующий глаз».</p></sec><sec><title>Результаты</title><p>Результаты. Получены разные соотношения ЛФ в обследуемых группах детей (p &lt; 0,001). Соотношение правши/левши/амбидекстры наиболее равномерным было в группе детей с содружественным косоглазием (43,8/22,5/33,7 %). В группе детей с органической офтальмопатологией оно было сдвинуто в сторону правшей (65,8/10,8/23,4 %). В контрольной группе количество левшей было минимальным, а количество амбидекстров — максимальным (51,4/3,9/44,7 %).</p></sec><sec><title>Заключение</title><p>Заключение. Установлено, что для детей с органической офтальмопатологией характерно наиболее выраженное преобладание правосторонних ЛФ, а для детей с содружественным косоглазием — относительно равномерное распределение правосторонних, левосторонних и симметричных ЛФ. Выявленные особенности могут отражать повышенную левополушарную активность у детей с органической офтальмопатологией и адаптационно-компенсаторное усиление активности правого полушария у детей с содружественным косоглазием. </p></sec></abstract><trans-abstract xml:lang="en"><p>The work is devoted to one of the most relevant problems of ophthalmology and neurophysiology which is the study of interhemispheric interactions in children with ophthalmopathology.</p><p>The purpose of this work is to study lateral phenotypes in children with ophthalmopathology.</p><sec><title>Patients and methods</title><p>Patients and methods. 374 6–15 years old children were observed: 1) 160 children with non-paralytic strabismus; 2) 111 children with organic pathology of the retina and the optic nerve; 3) 103 children of the control group (without ophthalmopathology). The lateral phenotype (LP) was determined according to the scheme “dominant hand — dominant ear — dominant eye”.</p></sec><sec><title>Results</title><p>Results. Different LP ratios were obtained in the examined groups of children (p &lt; 0.001). The ratio of right-handers / left-handers / ambidextrous children was most uniform in the group of children with non-paralytic strabismus (43,8 / 22,5 / 33,7 %). In the group of children with organic ophthalmopathology it was “shifted” to the right-hand side (65,8 / 10,8 / 23,4 %). In the control group the number of left-handers was minimal, and the number of ambidextrous was maximal (51,4 / 3,9 / 44,7).</p></sec><sec><title>Conclusion</title><p>Conclusion. It was found that children with organic ophthalmopathology are characterized by the most pronounced predominance of right-sided LP, and children with non-paralytic strabismus are characterized by a relatively uniform distribution of right-sided, left-sided and symmetrical LP. The identified features may reflect increased left-hemispheric activity in children with organic ophthalmopathology and adaptivecompensatory increase in right-hemispheric activity in children with non-paralytic strabismus. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>латеральные фенотипы</kwd><kwd>межполушарная асимметрия</kwd><kwd>офтальмопатология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lateral phenotypes</kwd><kwd>interhemispheric asymmetry</kwd><kwd>ophthalmopathology</kwd><kwd>functional treatment of strabismus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Atkinson J. The developing visual brain. New York: Oxford University Press, 2000. 176 p.</mixed-citation><mixed-citation xml:lang="en">Atkinson J. The developing visual brain. 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