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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2022-4-740-745</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-1978</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Инновационные технологии в мониторинге возрастной катаракты</article-title><trans-title-group xml:lang="en"><trans-title>Innovative Technologies in the Monitoring of the Age-Related Cataract</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселева</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiseleva</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, начальник отдела ультразвуковых исследований </p><p> ул. Садовая-Черногрязская, 14/19, Москва, 105062, Российская Федерация </p></bio><bio xml:lang="en"><p>MD, Professor, head of Ultrasound diagnostic department</p><p>Sadovaya‑Chernogryazskaya str., 14/19, Moscow, 105062, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник</p><p>ул. Садовая‑Черногрязская, 14/19, Москва 105062, Российская Федерация </p></bio><bio xml:lang="en"><p>junior researcher</p><p>Sadovaya‑Chernogryazskaya str., 14/19, Moscow, 105062, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр глазных болезней им. Гельмгольца» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2022</year></pub-date><volume>19</volume><issue>4</issue><fpage>740</fpage><lpage>745</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Киселева Т.Н., Зайцев М.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Киселева Т.Н., Зайцев М.С.</copyright-holder><copyright-holder xml:lang="en">Kiseleva T.N., Zaitsev M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/1978">https://www.ophthalmojournal.com/opht/article/view/1978</self-uri><abstract><p>Обзор литературы посвящен современным высокотехнологичным инструментальным методам исследования хрусталика, внедрение которых в клиническую офтальмологическую практику необходимо для повышения эффективности диагностики и лечения катаракты. Для субъективной оценки катаракты в соответствии с классификацией LOCS III используют биомикроскопию и регистрацию изображений хрусталика в отраженном свете с ретроиллюминацией. В последние годы практическую значимость приобретают объективные методы исследования хрусталика, которые позволяют наиболее точно определять ранние возрастные изменения хрусталика с количественной оценкой степени выраженности помутнений. К ним относятся оптические и ультразвуковые методы. Оптические методы включают денситометрию с использованием Шеймпфлюг-камеры и компьютерных программ для определения локализации помутнений и скорости их прогрессирования, а также анализ распределения волнового фронта аберраций в зависимости от степени выраженности катаракты с определением объективного индекса светорассеяния (OSI), используя диагностическую систему double-pass technology. Оптическим методом количественной оценки помутнений хрусталика является измерение аберраций оптической системы глаза с использованием датчика волнового фронта Шэка — Гартмана для выявления различных стадий ядерных помутнений (N-тип) соответственно категориям классификации LOCS III, обладающего высокой информативностью при ядерной катаракте. Новая технология Swept source — оптическая когерентная томография (SS-OКT) с переменной длиной волны и высокочастотным детектором — позволяет проводить денситометрию помутнений в кортикальных слоях и ядре хрусталика с функцией картирования изображения помутнений в микро- и макромасштабе. Среди методов эхографии наиболее информативной в оценке возрастных изменений хрусталика и определении его акустической плотности является ультразвуковая биомикроскопия (УЗБМ). Современные высокоинформативные методы количественной оценки оптической плотности хрусталика становятся необходимыми для определения показаний к своевременному хирургическому вмешательству, выбора оптимальных режимов факоэмульсификации и предотвращения интраоперационных осложнений. Высокотехнологичные оптические методы мониторинга катаракты позволили установить в ряде клинических исследований эффективность коррекции начальных возрастных помутнений хрусталика при использовании 0,005 % раствора пиреноксина.</p></abstract><trans-abstract xml:lang="en"><p>Literature review is devoted to modern high-technology instrumental methods of the lens evaluation, which have been developed to improve efficiency of the diagnostics and management of cataract in ophthalmological clinical practice. The slit-lamp examination of lens and retroillumination images are used for subjective assessment of cataract according to LOCS III grading system. Currently objective methods of lens evaluation have practical value and provide information about early age-related changes of crystalline lens with the quantitative assessment of the severity of opacities including the optical and ultrasound examinations. Optical methods include densitometry using Scheimpflug images obtained from applications to quantify the localization of lens opacities and their progression rate. Another method is the intensity distribution analysis of the wave front of the optical aberrations according to grading cataract severity with the objective scatter index (OSI) obtained by double-pass technology. Moreover the optical quantitative assessment of lens opacities is carried out by the Shack—Hartmann wave front sensor to identify the grade of nuclear opalescence (N-type) with the Lens Opacities Classification System III. This method is very helpful in nuclear cataract. Swept source optical coherent tomography (SS-OCT) with variable length of wave and high frequency detector is used for the density measurements of nuclear and cortical opacities of lens imaging in micro- and macro dimensional scale. Ultrasound biomicroscopy is the most informative ultrasonic diagnostic method for the evaluation of acoustic density and early age-related changes of lens. Current high-informative methods of quantitative assessment of the optical density of lens are helpful in determination of indications for surgery, the optimization of phacoemulsification settings and prevention of intraoperative complications. The use of high-technologic methods demonstrated the effectiveness of eye drops 0,005 % pirenoxine in early lens opacities management.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная катаракта</kwd><kwd>хрусталик</kwd><kwd>оптические методы</kwd><kwd>Шеймпфлюг-камера</kwd><kwd>объективный индекс светорассеяния</kwd><kwd>оптическая плотность</kwd><kwd>оптическая когерентная томография</kwd><kwd>ультразвуковая биомикроскопия</kwd><kwd>акустическая плотность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>age-related cataract</kwd><kwd>lens</kwd><kwd>optical methods</kwd><kwd>Scheimpflug images</kwd><kwd>objective scatter index</kwd><kwd>optical coherent tomography</kwd><kwd>ultrasound biomicroscopy</kwd><kwd>acoustic density</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Коняев Д.А., Попова Е.В., Титов А.А. 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