ophthalmologyОфтальмологияOphthalmology in Russia1816-50952500-0845Ophthalmology10.18008/1816-5095-2022-4-898-905ophthalmology-2003Research ArticleКЛИНИЧЕСКИЙ СЛУЧАЙCASE REPORTОстрый гнойный кератит смешанной этиологии, развившийся на фоне ношения контактных линз. Клинический случайAcute Purulent Keratitis of Mixed Etiology Developed during Contact Lens Wearing. Clinical Casehttps://orcid.org/0000-0001-8594-2395КаспароваЕвг. А.KasparovaEvg. A.

кандидат медицинских наук, ведущий научный сотрудник отдела патологии оптических сред глаза

ул. Россолимо, 11а, б, Москва, 119021, Российская Федерация

PhD, leading research officer of the Optical media of the eye pathology department

Rossolimo str., 11A, B, Moscow, 119021, Russian Federation 

https://orcid.org/0000-0001-6945-237XМарченкоН. Р.MarchenkoN. R.

кандидат медицинских наук, ведущий научный сотрудник отдела патологии оптических сред глаза

ул. Россолимо, 11а, б, Москва, 119021, Российская Федерация

PhD, research officer of the Optical media of the eye pathology department

Rossolimo str., 11A, B, Moscow, 119021, Russian Federation 

https://orcid.org/0000-0002-2931-0796НарбутМ. Н.NarbutM. N.

младший научный сотрудник отдела патологии оптических сред глаза

ул. Россолимо, 11а, б, Москва, 119021, Российская Федерация

 junior researcher

Rossolimo str., 11A, B, Moscow, 119021, Russian Federation 

https://orcid.org/0000-0001-5692-1800СурнинаЗ. В.SurninaZ. V.

кандидат медицинских наук, старший научный  сотрудник отдела патологии оптических сред глаза

ул. Россолимо, 11а, б, Москва, 119021, Российская Федерация

PhD, senior researcher of the Department of pathology of the optical media of the eye

Rossolimo str., 11A, B, Moscow, 119021, Russian Federation 

https://orcid.org/0000-0001-6974-7872КриволаповаД. А.KrivolapovaD. A.

врач‑ординатор

ул. Россолимо, 11а, б, Москва, 119021, Российская Федерация

ophthalmology resident

Rossolimo str., 11A, B, Moscow, 119021, Russian Federation 

ФГБНУ «Научно-исследовательский институт глазных болезней имени М.М. Краснова»РоссияM.M. Krasnov Scientific Research Institute of Eye DiseasesRussian Federation202203012023194898905Copyright © Каспарова Е.А., Марченко Н.Р., Нарбут М.Н., Сурнина З.В., Криволапова Д.А., 20232023Каспарова Е.А., Марченко Н.Р., Нарбут М.Н., Сурнина З.В., Криволапова Д.А.Kasparova E.A., Marchenko N.R., Narbut M.N., Surnina Z.V., Krivolapova D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ophthalmojournal.com/opht/article/view/2003

 В статье представлено описание клинического случая развитого гнойного кератита смешанной  этиологии (синегнойная палочка + акантамеба), развившегося вследствие нарушения режима  ношения мягкой контактной линзы. При  конфокальной микроскопии роговицы обнаружены  множественные округлые гиперрефлективные  образования (цисты акантамебы). Комплексная противоинфекционная консервативная терапия в  сочетании с модифицированным кросслинкингом  позволила купировать бурно прогрессирующий гнойный кератит и повысить остроту зрения с 0,01  до 0,9. 

 The article presents a description of a clinical case of advanced purulent keratitis of mixed etiology (Pseudomonas aeruginosa + acanthamoeba),  developed as a result of a mode violation of soft contact lens wearing.  Confocal microscopy of the cornea revealed multiple rounded hyperreflective formations (acanthamoeba cysts). Complex anti-infective conservative therapy in combination with modified crosslinking stops rapidly progressing purulent keratitis and increases visual acuity from 0.01 to 0.9. 

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The authors declare that there are no conflicts of interest present.