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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2022-4-906-916</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2004</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>Клинический опыт хирургического и терапевтического лечения начальной стадии глаукомы при наблюдении пациента в течение 22 лет</article-title><trans-title-group xml:lang="en"><trans-title>The Clinical Experience of 22 Years Analysis of Therapeutic and Surgical Treatment of the Early Glaucoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макашова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Мakashova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, старший научный сотрудник</p><p>ул. Россолимо, 11a, б, Москва, 119021, Российская Федерация </p></bio><bio xml:lang="en"><p>MD, senior research officer</p><p>Rossolimo str., 11A, B, Moscow, 119021, Russian Federation </p></bio><email xlink:type="simple">nvmakashova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, руководитель отделения офтальмологии</p><p>Ленинский проспект, 90, Москва, 119021, Российская Федерация </p></bio><bio xml:lang="en"><p>PhD, head of the Department of ophthalmology</p><p>Leninsky ave., 90, Moscow, 119021, Russian Federation </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт глазных болезней имени М.М. Краснова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.M. Krasnov Scientific Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО Медицинский центр «Столица»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Center “Capital”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2023</year></pub-date><volume>19</volume><issue>4</issue><fpage>906</fpage><lpage>916</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макашова Н.В., Васильева А.Е., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Макашова Н.В., Васильева А.Е.</copyright-holder><copyright-holder xml:lang="en">Мakashova N.V., Vasilyeva A.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2004">https://www.ophthalmojournal.com/opht/article/view/2004</self-uri><abstract><p>Представлен клинический случай 22-летнего наблюдения за пациентом с начальной стадией глаукомы, у которого в течение первых 12 лет после хирургического вмешательства на фоне полной компенсации внутриглазного давления наблюдалась стабилизация зрительных функций, а в течение последующих 10 лет из-за низкой комплаентности, недостаточного соблюдения медикаментозного режима заболевание постепенно прогрессировало в развитую стадию. В итоге в 2021 г. появились выраженные изменения в поле зрения левого глаза, основной причиной которых, вероятно, стала сосудистая катастрофа на фоне низкого перфузионного давления и некомпенсированного ВГД. После тщательного анализа и подбора препаратов ВГД было компенсировано с помощью лазерного метода лечения и препарата «Дортимол Антиглау ЭКО», который показал лучшие результаты переносимости и достижения толерантного давления. В статье представлены данные клинико-инструментальных исследований, проанализированы факторы, отражающие важность оценки уровня комплаентности для снижения вероятности прогрессирования глаукомы и возникновения острых сосудистых нарушений из-за низкого перфузионного давления.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the clinical case of a 22-year follow-up of a patient with early glaucoma whose visual functions were stabilized during the first 12 years after trabeculectomy and during the next 10 years of therapeutic treatment due to poor compliance the disease progressed to advanced glaucoma. As a result, in 2021 there were pronounced changes in the visual field of the left eye, the main cause, probably, was a vascular accident against the background of low perfusion pressure and uncompensated IOP. After a thorough analysis and scrupulous selection of eyedrops, IOP was compensated with laser and instillation of Dortimol Antiglau, which showed the best results of tolerability and achievement of tolerant pressure. This article presents data from clinical and instrumental studies and analyzes factors reflecting the importance of assessing the level of compliance in reducing the glaucoma progression.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>глаукома</kwd><kwd>комплаентность</kwd><kwd>трабекулэктомия</kwd><kwd>начальная глаукома</kwd><kwd>несоблюдение медикаментозного режима</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glaucoma</kwd><kwd>compliance</kwd><kwd>trabeculectomy</kwd><kwd>early glaucoma</kwd><kwd>poor medication adherence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Malihi M., Moura Filho E.R., Hodge D.O., et al. 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