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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2014-4-32-40</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-203</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL &amp; EXPERIMENTAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Возможности применения ультразвуковой биомикроскопии в оценке состояния век и конъюнктивы</article-title><trans-title-group xml:lang="en"><trans-title>Ultrasound biomicroscopy as a tool for conjunctiva and eyelids evaluation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубилин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubilin</surname><given-names>V. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полунина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Polunina</surname><given-names>E. G.</given-names></name></name-alternatives><email xlink:type="simple">lpolunina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куренков</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurenkov</surname><given-names>V. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Институт повышения квалификации Федерального медико-биологического агентства», Москва, Россия; д. 15, ул. Гамалеи, Москва, 123098, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal institute of the professional development, Federal medical and biological agency, Moscow, Russia; 15, str. Gamalei, Moscow, 123098, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2015</year></pub-date><volume>11</volume><issue>4</issue><fpage>32</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трубилин В.Н., Полунина Е.Г., Куренков В.М., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Трубилин В.Н., Полунина Е.Г., Куренков В.М.</copyright-holder><copyright-holder xml:lang="en">Trubilin V.N., Polunina E.G., Kurenkov V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/203">https://www.ophthalmojournal.com/opht/article/view/203</self-uri><abstract><p>В результате изучения современных диагностических возможностей была предпринята попытка визуализации мейбомиевых желез с последующей оценкой их морфо-функционального состояния при помощи ультразвуковой биомикроскопии, которая в настоящее время является единственной методикой, позволяющей за счет применения датчика с повышенной чувствительностью и рабочей частотой сканирования до 50‑100 МГц проникать в ткань на глубину 4 мм. Пациенты: УБМ век была проведена в группе из 14 пациентов в возрасте от 29 до 81 года, как с заведомо выявленными проявлениями дисфункции мейбомиевых желез (ДМЖ), так и с их нормальным функциональным состоянием. У 6пациентов отсутствовали биомикроскопические признаки блефарита, у 8 — имели место биомикроскопические признаки блефарита, блефароконъюнктивита и дисфункции мейбомиевых желез. Результаты и обсуждение: установлено, что УБМ позволяет получать детальную информацию как о состоянии нормальных структур реберного края век и мейбоимевых желез, так и о проявлении их патологических состояний, таких как утолщение реберного края век, развившегося вследствие воспаления, закупорка протоков устьев мейбомиевых желез, расширение просвета между мейбомиевыми железами, развившееся вследствие атрофичесих изменений желез, деструкции хрящевой ткани. Результаты проводимого исследования — УБМ структур век, возможно, зависят от возраста пациента, стадии и степени выраженности заболевания. Находкой явилась возможность визуализации буллезноизмененной конъюнктивы, а также субконъюнктивальных кист при изменении угла наклонадатчика, что особенно важно при проведении дифференциальной диагностики между кистами с мутным содержимым и новообразованиями. Комбинированное использование ультразвуковой биомикроскопии в комплексе с другими стандартными исследованиями дает возможность существенно повысить информативность, надежность и точность диагностики патологических изменений переднего отрезка глаза, и, следовательно, разрабатывать патогенетически направленные схемы лечения. Учитывая высокую значимость и информативность полученных результатов, можно сделать вывод, что необходимо продолжить исследования в этой области с изучением диагностических возможностей ультразвуковой биомикроскопии век и конъюнктивы.</p></abstract><trans-abstract xml:lang="en"><p>Currently, ultrasound biomicroscopy (UBM) is the only diagnostic method that uses a 50‑100 MHz transducer with a depth of penetration of 4 mm. This provides greater sensitivity and resolution.</p><sec><title>Aim</title><p>Aim. To visualize meibomian glands and to evaluate their morphological and functional status using UBM.</p></sec><sec><title>Methods</title><p>Methods. UBM was performed in 14 patients aged 29‑81 with obvious meibomian gland dysfunction (MGD) and healthy meibomian glands. 6 patients had no biomicroscopic signs of blepharitis while 8 patients had biomicroscopic signs of blepharitis, blepharoconjunctivitis, and MGD.</p></sec><sec><title>Results</title><p>Results. UBM provides detailed information on meibomian glands and eyelid margins and their pathological conditions, i.e., eyelid margin thickening due to inflammation, meibomian gland orifice obstruction, increase in distance between meibomian glands due to their atrophy, and cartilaginous tissue destruction. UBM findings may depend on patient age as well as on disease stage and severity. When re-positioning UBM transducer, bullous conjunctiva and subconjunctival cysts can be visualized. This provides differential diagnosis between opaque cysts and tumors.</p></sec><sec><title>Conclusion</title><p>Conclusion. UBM combined with standard exams increases information value, reliability, and accuracy of the diagnostics of anterior segment disorders and facilitates the development of targeted therapeutic approaches. Further studies on diagnostic value of conjunctiva and eyelids UBM are required.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ультразвуковая биомикроскопия</kwd><kwd>мейбомиевы железы</kwd><kwd>конъюнктива</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ultrasound biomicroscopy</kwd><kwd>meibomian glands</kwd><kwd>conjunctiva.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pavlin CJ, Harasiewicz K, Foster FS. Ultrasound biomicroscopy of anterior segment structures in normal and glaucomatous eyes. Am J Ophthalmol. 1992;113:381‑9.</mixed-citation><mixed-citation xml:lang="en">Pavlin CJ, Harasiewicz K, Foster FS. Ultrasound biomicroscopy of anterior segment structures in normal and glaucomatous eyes. 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