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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2023-1-5-16</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2036</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Биоинженерия в офтальмологии. Обзор</article-title><trans-title-group xml:lang="en"><trans-title>Ophthalmic Bioengineering. Review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2353-9610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарев</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomarev</surname><given-names>V. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пономарев Вячеслав Олегович - кандидат медицинских наук, врач‑офтальмохирург, заместитель генерального директора по научно‑клинической работе</p><p>ул. Академика Бардина, 4а, Екатеринбург, 620149, Российская Федерация </p></bio><bio xml:lang="en"><p>Ponomarev Vyacheslav O. - PhD, ophthalmic surgeon, deputy general director for scientific and clinical work</p><p>Academician Bardin str., 4A, Yekaterinburg, 620149, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4725-3681</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жданов</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhdanov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жданов Алексей Евгеньевич - инженер‑исследователь института радиоэлектроники и информационных технологий</p><p>ул. Мира, 32, Екатеринбург, 620078, Российская Федерация </p></bio><bio xml:lang="en"><p>Zhdanov Aleksei E. - research engineer</p><p>Mira str., 32, Ekaterinburg, 620078, Russian Federation </p></bio><email xlink:type="simple">a.e.zhdanov@urfu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1111-7063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лужнов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Luzhnov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лужнов Петр Вячеславович - кандидат технических наук, доцент</p><p>ул. 2-я Бауманская, 5, стр. 1, Москва, 105005, Российская Федерация </p></bio><bio xml:lang="en"><p>Luzhnov Petr V. - PhD of Engineering, Associate Professor</p><p>2nd Baumanskaya str., 5, bld. 1, Moscow, 105005, Russian Federation </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдова</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydova</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Давыдова Ирина Денисовна - магистрант </p><p>ул. 2-я Бауманская, 5, стр. 1, Москва, 105005, Российская Федерация </p></bio><bio xml:lang="en"><p>Davydova Irina D. - student</p><p>2nd Baumanskaya str., 5, bld. 1, Moscow, 105005, Russian Federation </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8143-3606</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иомдина</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Iomdina</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иомдина Елена Наумовна - доктор биологических наук, профессор, главный научный сотрудник</p><p>ул. Садовая-Черногрязская, 14/19, Москва, 105062, Российская Федерация </p></bio><bio xml:lang="en"><p>Iomdina Elena N. - Professor, Dr. of Biological Sciences, principal researcher</p><p>Sadovaya‑Chernogryazskaya str., 14/19, Moscow, 105062, Russian Federation </p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7019-3002</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лизунов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lizunov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лизунов Александр Владиленович - врач‑офтальмологул. Академика Бардина, 4а, Екатеринбург, 620149, Российская Федерация </p></bio><bio xml:lang="en"><p>Lizunov Alexandr V. - ophthalmologist</p><p>Academician Bardin str., 4A, Yekaterinburg, 620149, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2318-9144</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долганов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolganov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Долганов Антон Юрьевич - кандидат технических наук, доцент и младший научный сотрудник института радиоэлектроники и информационных технологий</p><p>ул. Мира, 32, Екатеринбург, 620078, Российская Федерация </p></bio><bio xml:lang="en"><p>Dolganov Anton Yu. - PhD of Engineering, Associate Professor and junior researcher</p><p>Mira str., 32, Yekaterinburg, 620078, Russian Federation </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2860-2711</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивлиев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivliev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивлиев Сергей Андреевич - кандидат технических наук, доцент института информационных и вычислительных технологий</p><p>ул. Красноказарменная, 14, Москва, 111250, Российская Федерация </p></bio><bio xml:lang="en"><p>Ivliev Sergey A. - PhD of Engineering, Associate Professor</p><p>st. Krasnokazarmennaya, 14, Moscow, 111250, Russian Federation </p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Знаменская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Znamenskaya</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Знаменская Мария Андреевна - доктор медицинских наук, медицинский директор </p><p>ул. Саут Стейт, 100, Чикаго, IL 60603, Соединенные Штаты Америки </p></bio><bio xml:lang="en"><p>Znamenskaya Maria A. - MD, Medical Director</p><p>South State str., 100, Chicago, IL 60603, USA </p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9569-5906</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казайкин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazajkin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казайкин Виктор Николаевич - доктор медицинских наук, ведущий научный сотрудник</p><p>ул. Академика Бардина, 4а, Екатеринбург, 620149, Российская Федерация </p></bio><bio xml:lang="en"><p>Kazajkin Viktor N. - MD, leading researcher</p><p>Academician Bardin str., 4A, Yekaterinburg, 620149, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0486-7552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Борисов Василий Ильич - кандидат технических наук, доцент института радиоэлектроники и информационных технологий</p><p>ул. Мира, 32, Екатеринбург, 620078, Российская Федерация </p></bio><bio xml:lang="en"><p>Borisov Vasilii I. - PhD of Engineering, Associate Professor</p><p>Mira str., 32, Yekaterinburg, 620078, Russian Federation </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2860-2711</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филатова</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Filatova</surname><given-names>E. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филатова Екатерина Олеговна - студентка института информационных и вычислительных технологийул. Красноказарменная, 14, Москва, 111250, Российская Федерация </p></bio><bio xml:lang="en"><p>Filatova Ekaterina O. - student</p><p>Krasnokazarmennaya str., 14, Moscow, 111250, Russian Federation </p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>АО «Екатеринбургский центр МНТК “Микрохирургия глаза”» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Eye Microsurgery Ekaterinburg Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Уральский федеральный университет имени первого Президента России Б.Н. Ельцина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Federal University named after the First President of Russia B.N. Yeltsin</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный технический университет имени Н.Э. Баумана»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bauman Moscow State Technical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center for Eye Diseases of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВПО «Национальный исследовательский университет “МЭИ”»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research University “Moscow Power Engineering Institute”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Altris Inc.</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>Altris Inc.</institution><country>United States</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>03</day><month>04</month><year>2023</year></pub-date><volume>20</volume><issue>1</issue><fpage>5</fpage><lpage>16</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пономарев В.О., Жданов А.Е., Лужнов П.В., Давыдова И.Д., Иомдина Е.Н., Лизунов А.В., Долганов А.Ю., Ивлиев С.А., Знаменская М.А., Казайкин В.Н., Борисов В.И., Филатова Е.О., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Пономарев В.О., Жданов А.Е., Лужнов П.В., Давыдова И.Д., Иомдина Е.Н., Лизунов А.В., Долганов А.Ю., Ивлиев С.А., Знаменская М.А., Казайкин В.Н., Борисов В.И., Филатова Е.О.</copyright-holder><copyright-holder xml:lang="en">Ponomarev V.O., Zhdanov A.E., Luzhnov P.V., Davydova I.D., Iomdina E.N., Lizunov A.V., Dolganov A.Y., Ivliev S.A., Znamenskaya M.A., Kazajkin V.N., Borisov V.I., Filatova E.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2036">https://www.ophthalmojournal.com/opht/article/view/2036</self-uri><abstract><p>В настоящей статье опубликованы материалы круглого стола «Биоинженерия в офтальмологии» (Ophthalmic Bioengineering), проведенного 13 мая 2021 г. в рамках международной конференции «Уральский симпозиум по биомедицинской инженерии, радиоэлектронике и информационным технологиям — 2021» (USBEREIT) (2021 Ural Symposiumon Biomedical Engineering, Radioelectronicsand Information Technology). USBEREIT проводился под эгидой IEEE Engineering in Medicine and Biology Society — международной некоммерческой ассоциации инженеров в области медицины и биологии. В статье представлены доклады, посвященные метрологическим аспектам регистрации тонометрических и электрофизиологических сигналов в офтальмологической диагностике; подходам к моделированию процессов пульсового кровенаполнения глаза с определением показателей гемодинамики; ретинотоксичности на базе электрофизиологических сигналов; анализу электрофизиологических сигналов в частотно-временной области и его применению в клинической практике; извлечению и анализу специализированных данных, получаемых с помощью электрофизиологического медицинского аппарата; а также диагностированию заболеваний сетчатки на базе оптической когерентной томографии с использованием машинного обучения.</p></abstract><trans-abstract xml:lang="en"><p>This article published the materials of the round table “Bioengineering in ophthalmology” (OphthalmicBioengineering), held on May 13, 2021 as part of the international conference Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT). USBEREIT is held under the auspices of the IEEE Engineering in Medicine and Biology Society. The article presents reports on: metrological aspects of registration of tonometric and electrophysiological signals in ophthalmic diagnostics; approaches to modeling the processes of pulse blood filling of the eye with the determination of hemodynamic parameters; retinotoxicity based on electrophysiological signals; analysis of electrophysiological signals in the frequency-time domain and its application in clinical practice; extraction and analysis of specialized data obtained from the electrophysiological medical device; as well as diagnosing retinal diseases based on optical coherence tomography using machine learning.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колебания глазного кровотока</kwd><kwd>внутриглазное давление</kwd><kwd>гемодинамика</kwd><kwd>реоофтальмография</kwd><kwd>объем сосудистой оболочки</kwd><kwd>кровоток глаза</kwd><kwd>ретинотоксичность</kwd><kwd>электрофизиологические исследования</kwd><kwd>электроретинография</kwd><kwd>ЭРГ</kwd><kwd>спектрограмма</kwd><kwd>вейвлет-скалограмма</kwd><kwd>Фурье-анализ</kwd><kwd>Roland</kwd><kwd>Tomey</kwd><kwd>файлы бинарного формата</kwd><kwd>извлечение данных</kwd><kwd>ОКТ</kwd><kwd>машинное обучение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fluctuations in ocular blood flow</kwd><kwd>intraocular pressure</kwd><kwd>reoophthalmography</kwd><kwd>hemodynamics</kwd><kwd>choroid volume</kwd><kwd>ocular blood flow</kwd><kwd>retinotoxicity</kwd><kwd>electrophysiological studies</kwd><kwd>electroretinography</kwd><kwd>ERG</kwd><kwd>spectrogram</kwd><kwd>wavelet scalogram</kwd><kwd>Fourier analysis</kwd><kwd>Roland</kwd><kwd>Tomey</kwd><kwd>binary format files</kwd><kwd>data extraction</kwd><kwd>OCT</kwd><kwd>machine learning</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках научной темы рег. № НИОКТР АААА-А19- 119021190151-3</funding-statement><funding-statement xml:lang="en">The work was carried out within the framework of a scientific topic reg. № REDTW АААА-А19- 119021190151-3</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shetty D. 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