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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2014-4-47-53</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL &amp; EXPERIMENTAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Морфо-функциональная характеристика органа зрения у пациентов с вибрационной болезнью</article-title><trans-title-group xml:lang="en"><trans-title>Morphological and functional characteristics of an eye in vibration disease patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышева</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Malysheva</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">svess@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное бюджетное образовательное учреждение высшего профессионального образования Тюменская государственная медицинская академия Министерства здравоохранения Российской&#13;
Федерации, ул. Одесская, д.54, г. Тюмень, 625023, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen state medical academy of Ministry of Health of Russia, ophthalmology chair, Tyumen, Odesskay st. 54, Tyumen, 625023, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное образовательное учреждение высшего профессионального образования&#13;
Тюменская государственная медицинская академия Министерства здравоохранения Российской&#13;
Федерации, ул. Одесская, д.54, г. Тюмень, 625023, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen state medical academy of Ministry of Health of Russia, ophthalmology chair, Tyumen, Odesskay st. 54, Tyumen, 625023,&#13;
Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2015</year></pub-date><volume>11</volume><issue>4</issue><fpage>47</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малышева С.С., Петров С.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Малышева С.С., Петров С.А.</copyright-holder><copyright-holder xml:lang="en">Malysheva S.S., Petrov S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/205">https://www.ophthalmojournal.com/opht/article/view/205</self-uri><abstract><sec><title>Цель</title><p>Цель: Оценить офтальмоскопическую картину глазного дна и данные компьютерной периметрии у лиц с вибрационной болезнью в зависимости от видов высокочастотных воздействий.</p></sec><sec><title>Методы</title><p>Методы: обследовано 62 больных вибрационной болезнью 1‑2 ст. Возраст обследуемых составил от 40 до 65 лет (средний возраст 55,69±0,7). Пациенты были разделены по виду воздействующей вибрации на 2 группы: I группа — локальное воздействие вибрации (30 чел., 49,2 %); II группа — комбинированное воздействие вибрации (32 чел., 50,8 %). В контрольную группу вошли лица, не имевшие контакта с вибрацией, соматически здоровые. Проанализированы данные офтальмоскопии, выполненные с помощьюнемидриатической фундус камеры Topcon TRC-NW300, и данные компьютерной периметрии. При анализе полей зрения использовали тест Glauсoma threshol — исследование центрального поля зрения, расположенного в пределах 30° от точки фиксации.</p></sec><sec><title>Результаты</title><p>Результаты: У пациентов с вибрационной болезнью наблюдается расширенная экскавация ДЗН, нарушение правила ISNT, перипапиллярная атрофия. Встречаются кровоизлияния на ДЗН и стушеванность контуров ДЗН. Количество ДЗН большого размера было больше в группе комбинированного воздействиявибрации, а ДЗН среднего размера — в группе локального воздействия. У пациентов вне зависимости от вида воздействия вибрации, развивались дистрофические и геморрагические изменения в центральной зоне сетчатки. При анализе показателей компьютерной периметрии MD, PSD, SF и GPSD у лиц с ВБ были выявлены достоверные различия с контрольной группой (снижение показателя MD, повышение показателей PSD, SF и GPSD). Однако, анализируя вышеперечисленные показатели компьютерной периметрии, мы не обнаружили достоверных различий между группами комбинированного и локального воздействия вибрации. По данным компьютерной периметрии у лиц с ВБ наблюдается снижение светочувствительности фовелярной области центральной зоны сетчатки от 1 до 22 дБ. В группе комбинированного воздействия чувствительность сетчатки в пределах 5º от точки фиксации по сравнению с возрастной нормой снижается в большей степени по сравнению с группой локального воздействия вибрации.</p></sec><sec><title>Заключение</title><p>Заключение: у больных вибрационной болезнью со стажем работы более 10 лет формируется симптомо-комплекс, включающий офтальмоскопические признаки, характерные для оптической нейропатии. Хроническое воздействие вибрации проявляется дистрофическими изменениями, как со стороны зрительного нерва, так и со стороны центральной зоны сетчатки.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: To analyze ocular fundus photos and visual field test findings in vibration disease patients depending on highfrequencyexposition.</p></sec><sec><title>Methods</title><p>Methods: 62 vibration disease patients aged 40‑65 (55.69±0.7 years on average) were examined. The patients were divided into 2 groups depending on vibration exposition: group 1 (local exposition) included 30 patients (49.2 %), group 2 (combined exposition) included 32 patients (50.8 %). Healthy persons not exposed to vibration were controls. Non-mydriatic ophthalmoscopy was performed using fundus camera Topcon TRC-NW300. Threshold visual field test which covers central 30 degrees of field was performed as well.</p></sec><sec><title>Results</title><p>Results: In vibration disease patients, enlarged optic nerve excavation, violation of the ISNT rule, peripapillary atrophy, optic disc hemorrhages, and blurred disc margins were detected. Enlarged optic nerve head was observed in combined vibration exposition group while medium-sized optic nerve head was observed in local exposition group. Retinal dystrophy and hemorrhages were foundin the central area regardless of vibration exposition. The analysis of visual field test indices demonstrated that MD was significantly lower while PSD, SF, and GPSD were significantly higher in vibration disease patients as compared with controls. However, no significant difference was revealed between local and combined vibration exposition. Visual field test exam showed foveal light sensitivity reduction by 1‑22 dB. In combined vibration exposition group, decrease in retinal sensitivity within the central 5 degrees was greater than in local vibration exposition group.</p></sec><sec><title>Conclusion</title><p>Conclusion: Vibration disease patients with over 20 year-experience have signs of optic nerve damage (neuropathy). Chronic exposition to vibration provokes optic nerve atrophy and central retinal degeneration.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вибрационная болезнь</kwd><kwd>офтальмоскопия</kwd><kwd>компьютерная периметрия</kwd><kwd>оптическая нейропатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vibration disease</kwd><kwd>ophthalmoscopy</kwd><kwd>visual field test</kwd><kwd>optic neuropathy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Izmerov N. F. [Professional pathology. Nnational management] Nacional’noe rukovodstvo. Moskov 2011. 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