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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2023-3-398-404</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2163</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Методы лечения сухой формы возрастной макулярной дегенерации — история и перспективы. Обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5274-6993</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликов Алексей Николаевич, доктор медицинских наук, профессор, начальник кафедры (клиники) офтальмологии им. профессора В.В. Волкова</p><p>ул. Академика Лебедева, 6, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Kulikov Aleksey N., MD, Professor, head of the Ophthalmology department named after Professor V.V. Volkov</p><p>Academician Lebedev str., 6, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6549-3991</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захаров Михаил Владимирович, кандидат медицинских наук, заместитель начальника кафедры нефрологии и эфферентной терапии</p><p>ул. Академика Лебедева, 6, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Zakharov Mikhail V., PhD, deputy head of the Nephrology and efferent therapy department</p><p>Academician Lebedev str., 6, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5446-5063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воложев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volozhev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Воложев Александр Аркадьевич, адъюнкт кафедры офтальмологии им. профессора В.В. Волкова</p><p>ул. Академика Лебедева, 6, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Volozhev Aleksandr A., adjunct of the Ophthalmology department named after Professor V.V. Volkov</p><p>Academician Lebedev str., 6, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» Министерства обороны Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2023</year></pub-date><volume>20</volume><issue>3</issue><fpage>398</fpage><lpage>404</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Куликов А.Н., Захаров М.В., Воложев А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Куликов А.Н., Захаров М.В., Воложев А.А.</copyright-holder><copyright-holder xml:lang="en">Kulikov A.N., Zakharov M.V., Volozhev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2163">https://www.ophthalmojournal.com/opht/article/view/2163</self-uri><abstract><p>В настоящее время возрастная макулярная дегенерация является наиболее частой причиной прогрессирующего снижения зрения, ведущего к потере трудоспособности у лиц пожилого возраста. В обзоре освещены исторические аспекты этой проблемы, факторы риска заболевания, вопросы патогенеза и классификации, современные и перспективные направления лечения. Несмотря на огромные успехи в изучении этиологии и патогенеза и усовершенствовании методов диагностики возрастной макулярной дегенерации, ее лечение остается достаточно сложной проблемой. Пока в медицине отсутствует этиотропное лечение возрастной макулярной дегенерации в связи с тем, что конкретный этиологический фактор развития заболевания до сих пор не выявлен. Единственным доказанным патогенетическим методом лечения влажной формы возрастной макулярной дегенерации является антиVEGF-терапия. При сухой форме возрастной макулярной дегенерации лечебные мероприятия направлены на устранение факторов риска (отказ от курения, ведение здорового образа жизни и др.) и соблюдение рекомендаций по диетическому режиму или прием антиоксидантов, минерально-витаминных комплексов и пептидных биорегуляторов. Недостатком существующих методов лечения является узкая направленность действия на один из звеньев патогенеза или применение в качестве симптоматической терапии. Анализ литературы позволил отметить использование экстракорпоральной гемокоррекции как перспективное направление в поиске методов лечения сухой формы возрастной макулярной дегенерации.</p></abstract><trans-abstract xml:lang="en"><p>Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of that pathology. The causes of age-related macular degeneration are not fully understood, in spite of keeping a great amount of knowledge at etiology, pathogenesis, diagnosis and modern types of treatment. The problem of age-related macular degeneration treatment has remained actual nowadays. Now, the medicine doesn’t have etiotropic treatment of AMD, because we still don’t know a definite etiologic factor of this developing disease. The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. The disadvantage of current treatment methods is a narrow focus at one of the pathogenesis components or using as symptomatic therapy. The analysis of literature date has allowed noticing of using of an extracorporeal hemocorrection as perspective way at exploration of new methods of treatment of dry age-related macular degeneration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная макулярная дегенерация</kwd><kwd>лечение сухой формы ВМД</kwd><kwd>экстракорпоральная гемокоррекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>age-related macular degeneration</kwd><kwd>treatment of dry AMD</kwd><kwd>extracorporeal hemocorrection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Donders FC. Beiträge zur pathologischen Anatomie des Auges. Archiv Für Ophthalmologie. 1855;1(2):106–118.</mixed-citation><mixed-citation xml:lang="en">Donders FC. Beiträge zur pathologischen Anatomie des Auges. 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