References

ophthalmology

Офтальмология

Ophthalmology in Russia

1816-50952500-0845

Ophthalmology

10.18008/1816-5095-2024-1-5-15

ophthalmology-2287

Research Article

ОБЗОРЫ

REVIEWS

Клинические аспекты различных модификаций кросслинкинга роговичного коллагена

Clinical Aspects of Corneal Collagen Crosslinking Various Modifications

https://orcid.org/0000-0003-4043-456X

Юсеф

Ю. Н.

Yusef

Yu. N.

Юсеф Наим Юсеф — доктор медицинских наук, профессор, директор, офтальмохирург (высшая категория)

ул. Россолимо, 11а, б, Москва, 119021

Yusef N. Yusef — MD, Professor, Director, ophthalmosurgeon (highest category)

Rossolimo str., 11A, B, Moscow, 119021

https://orcid.org/0000-0001-6837-8008

Храйстин

Х.

Khraystin

Kh.

Храйстин Хусам — кандидат медицинских наук, научный сотрудник отдела патологии оптических сред глаза, офтальмохирург

ул. Россолимо, 11а, б, Москва, 119021,

ул. Лобачевского, 108, Москва, 119361

Husam Khraуstin — PhD, Researcher of the optical media of the eye pathology department, ophthalmosurgeon

Rossolimo str., 11A, B, Moscow, 119021,

Lobachevskogo str., 108, Moscow 119361

khrestin89@mail.ru

https://orcid.org/0000-0002-1056-4331

Осипян

Г. А.

Osipyan

G. A.

Осипян Григорий Альбертович — доктор медицинских наук, заведующий отделом патологии оптических сред глаза, офтальмохирург

ул. Россолимо, 11а, б, Москва, 119021,

ул. Лобачевского, 108, Москва, 119361

Grigory A. Osipyan — MD, head of the optical media of the eye pathology department, ophthalmosurgeon

Rossolimo str., 11A, B, Moscow, 119021,

Lobachevskogo str., 108, Moscow 119361

https://orcid.org/0000-0003-1922-4939

Анисимов

С. И.

Anisimov

S. I.

Анисимов Сергей Игоревич — профессор, доктор медицинских наук, офтальмохирург

ул. Делегатская, 20/1, Москва, 127473

Sergey I. Anisimov — Professor, MD, ophthalmosurgeon

Delegatskaya str., 20/1, Moscow, 127473

https://orcid.org/0000-0003-0966-4391

Журиех

М.

Jourieh

Журиех Мохаммад — аспирант

ул. Большая Пироговская, 2, стр. 4, Москва, 119435

Mohammad Jourieh — postgraduate

Bolshaya Pirogovskaya str., 2, bld. 4, Moscow, 119435

ФГБНУ «Научно-исследовательский институт глазных болезней им. М.М. Краснова»РоссияM.M. Krasnov Research Institute of Eye DiseasesRussian Federation

ФГБНУ «Научно-исследовательский институт глазных болезней им. М.М. Краснова»; Центр восстановления зренияРоссияM.M. Krasnov Research Institute of Eye Diseases; Vision Restoration CentreRussian Federation

ФГБОУ ВПО «Московский государственный медико-стоматологический институт им. А.И. Евдокимова» Министерства здравоохранения Российской ФедерацииРоссияV.I. Evdokimov Moscow State Medical and Dental InstituteRussian Federation

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» (Сеченовский университет) Министерства здравоохранения Российской ФедерацииРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University)Russian Federation

2024

30032024

211515

2024

Юсеф Ю.Н., Храйстин Х., Осипян Г.А., Анисимов С.И., Журиех М.

Yusef Y.N., Khraystin K., Osipyan G.A., Anisimov S.I., Jourieh M.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.ophthalmojournal.com/opht/article/view/2287

В обзоре представлены сведения о методах кросслинкинга роговичного коллагена (КРК) начиная с момента экспериментальных исследований и первых клинических наблюдений и до настоящего времени. Приведены данные о методиках и результатах различных модификаций КРК, а также о возможных перспективных направлениях в поиске путей совершенствования методики для улучшения функциональных результатов и снижения возможных осложнений. В настоящее время продолжаются не толь ко исследования по совершенствованию уже апробированных подходов при проведении КРК, но и поиск новых комбинаций и устройств.

The review provides information on methods for crosslinking corneal collagen (КРК), from the time of experimental studies and the first clinical observations to the present. Data are presented on the methods and results of CXL various modifications, as well as on possible promising directions for finding ways to improve the technique to improve functional results and reduce possible complications. Research is currently ongoing not only to improve already proven approaches for CXL, but also to search for new combinations and devices.

роговицакросслинкинг коллагена роговицыкератоконускератэктазияускоренный локальный кросслинкинг

corneacorneal collagen crosslinkingkeratoconuskeratectasiaaccelerated local crosslinking

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The authors declare that there are no conflicts of interest present.