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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-1-58-65</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2293</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Сроки применения перфторорганических соединений для тампонады витреальной полости после витрэктомии по поводу регматогенной отслойки сетчатки</article-title><trans-title-group xml:lang="en"><trans-title>Terms of Use of Perfluoroorganic Compounds for Intraocular Tamponade after Vitrectomy for Rhegmatogenous Retinal Detachment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Файзрахманов</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Fayzrakhmanov</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Файзрахманов Ринат Рустамович — доктор медицинских наук, профессор кафедры, заведующий кафедрой глазных болезней института усовершенствования врачей; заведующий Центром офтальмологии</p><p>ул. Нижняя Первомайская, 70, Москва, 105203;</p><p>ул. Нижняя Первомайская, 65, Москва, 105203</p></bio><bio xml:lang="en"><p>Fayzrakhmanov Rinat R. — MD, professor of the Eye Diseases Department, head of the Eye Diseases Department, Institute of Advanced Training of Physicians, head of Center of Ophthalmology </p><p>Nizhnyaya Pervomayskaya str., 70, Moscow, 105203, </p><p>Nizhnyaya Pervomayskaya str., 65, Moscow, 105203</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкин</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkin</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шишкин Михаил Михайлович — доктор медицинских наук, профессор, профессор кафедры глазных болезней института усовершенствования врачей; главный офтальмолог Центра офтальмологии</p><p>ул. Нижняя Первомайская, 70, Москва, 105203;</p><p>ул. Нижняя Первомайская, 65, Москва, 105203</p></bio><bio xml:lang="en"><p>Shishkin Michail M. — MD, professor, professor of the Eye Diseases Institute Department of Advanced Training of Physicians, the main ophthalmologist of Center of Ophthalmology </p><p>Nizhnyaya Pervomayskaya str., 70, Moscow, 105203, </p><p>Nizhnyaya Pervomayskaya str., 65, Moscow, 105203</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Larina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ларина Евгения Артемовна — кандидат медицинских наук, ассистент кафедры глазных болезней института усовершенствования врачей; врач-офтальмолог Центра офтальмологии</p><p>ул. Нижняя Первомайская, 70, Москва, 105203;</p><p>ул. Нижняя Первомайская, 65, Москва, 105203</p></bio><bio xml:lang="en"><p>Larina Evgenia A. — PhD, assistant of the Eye Diseases Institute Department of Advanced Training of Physicians, ophthalmologist of Center of Ophthalmology </p><p>Nizhnyaya Pervomayskaya str., 70, Moscow, 105203, </p><p>Nizhnyaya Pervomayskaya str., 65, Moscow, 105203</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2234-0914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ваганова</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Vaganova</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ваганова Елена Евгеньевна — аспирант кафедры глазных болезней</p><p>ул. Нижняя Первомайская, 65, Москва, 105203</p></bio><bio xml:lang="en"><p>Vaganova Elena E. — postgraduate of department of Eye Diseases Institute of Advanced Training of Physicians </p><p>Nizhnyaya Pervomayskaya str., 65, Moscow, 105203</p></bio><email xlink:type="simple">vaganova.e.e@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сехина</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sekhina</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сехина Ольга Леонидовна — аспирант кафедры глазных болезней</p><p>ул. Нижняя Первомайская, 65, Москва, 105203</p></bio><bio xml:lang="en"><p>Sekhina Olga L. — Postgraduate of department of Eye Diseases of Institute of Advanced Training of Physicians </p><p>Nizhnyaya Pervomayskaya str., 65, Moscow, 105203</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации;&#13;
Институт усовершенствования врачей ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.I. Pirogov National Medical Surgical Center;&#13;
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт усовершенствования врачей ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2024</year></pub-date><volume>21</volume><issue>1</issue><fpage>58</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Файзрахманов Р.Р., Шишкин М.М., Ларина Е.А., Ваганова Е.Е., Сехина О.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Файзрахманов Р.Р., Шишкин М.М., Ларина Е.А., Ваганова Е.Е., Сехина О.Л.</copyright-holder><copyright-holder xml:lang="en">Fayzrakhmanov R.R., Shishkin M.M., Larina E.A., Vaganova E.E., Sekhina O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2293">https://www.ophthalmojournal.com/opht/article/view/2293</self-uri><abstract><p>Перфторорганические соединения относятся к хирургически инвазивным медицинским изделиям и представляют собой жидкие фторсодержащие вещества, химически и биологически инертные и термодинамически стабильные из-за прочности химических связей между атомами углерода и фтора. Из-за плотности эти соединения способны оказывать давление на отслоенную сетчатку и вытеснять субретинальную жидкость. В настоящее время использование перфторорганических соединений ограничено интраоперационным применением из-за множественных тяжелых осложнений длительной тампонады. В проанализированных исследованиях применение перфторорганических соединений в качестве тампонирующего агента по длительности было разделено на краткосрочную и среднесрочную тампонаду витреальной полости. Авторы отдавали предпочтение именно такой тактике лечения в пользу восстановления анатомического прилегания и более высокой скорости созревания лазеркоагулятов сетчатки, несмотря на доказанные послеоперационные осложнения. На основании анализа результатов представленных исследований можно сделать вывод о возможности безопасного применения перфторорганических соединений для краткосрочной тампонады витреальной полости. Однако среди проанализированных отечественных и зарубежных исследований не было обнаружено широкомасштабных статистически достоверных исследований, обосновывающих выбор тампонирующего агента при разной локализации разрывов сетчатки, сроках отслойки сетчатки и стадии пролиферативной витреоретинопатии. Все вышесказанное определяет актуальность более детального изучения, касающегося применения перфторорганических соединений для краткосрочной тампонады витреальной полости.</p></abstract><trans-abstract xml:lang="en"><p>Perfluoroorganic compounds are surgically invasive medical devices, which are represent liquid fluorine-containing substances, chemically and biologically inert and thermodynamically stable due to the strength of chemical bonds between carbon and fluorine atoms. Due to their density, these compounds are able to exert pressure on the detached retina and expel the subretinal fluid. Currently, the use of perfluoroorganic compounds is limited to intraoperative use due to multiplesevere complications of prolonged tamponade. In the analyzed studies, the use of perfluoroorganic compounds as a tamponade was divided into short-term and medium-term tamponade of the vitreal cavity. The authors preferred such tactic for restoring the anatomical fit and a higher rate of aging of retinal laser coagulates, despite proven postoperative complications. Based on the analysis of the results of the presented studies, it can be concluded that it is possible to safely use perfluoroorganic compounds for short-term tamponade of the vitreal cavity. However, among the analyzed domestic and foreign studies, no large-scale statistically significant studies were found to justify the choice of tamponade for retinal breaks different localization, terms of retinal detachment and stage of proliferative vitreoretinopathy. All of that determines the relevance of a more detailed study of the use of perfluoroorganic compounds for short-term tamponade of the vitreal cavity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>регматогенная отслойка сетчатки</kwd><kwd>перфторорганические соединения</kwd><kwd>тампонада витреальной полости</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rhegmatogenous retinal detachment</kwd><kwd>perfluoroorganic compounds</kwd><kwd>tamponade of the vitreal cavity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Протокол Council directive 93/42/EEC of 14 June 1993. EUR-Lex Access to European Union law [размещено 11.10.2007, процитировано 01.09.2022]. Доступно: https://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CONSLEG:1993L0042:20071011:en:PDF</mixed-citation><mixed-citation xml:lang="en">Протокол Council directive 93/42/EEC of 14 June 1993. 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