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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-1-74-81</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2295</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOSURGERY</subject></subj-group></article-categories><title-group><article-title>Клинические особенности при проникающих ранениях глаза с инородным телом, осложненных развитием эндофтальмита</article-title><trans-title-group xml:lang="en"><trans-title>Clinical Features of Patients with Penetrating Eye Injury and Foreign Body Complicated by Endophthalmitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9204-9781</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абакаров</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abakarov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абакаров Сапиюлла Анварович — младший научный сотрудник офтальмологического отделения для взрослых </p><p>ул. Щепкина, 61/2, Москва, 123007</p></bio><bio xml:lang="en"><p>Abakarov Sapiyulla A. — research assistant, Ophthalmology department for adults</p><p>Shchepkina str., 61/2, Moscow, 123007</p></bio><email xlink:type="simple">boss@limesmedia.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0057-3338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лоскутов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Loskutov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лоскутов Игорь Анатольевич — доктор медицинских наук, руководитель офтальмологического отделения </p><p>ул. Щепкина, 61/2, Москва, 123007</p></bio><bio xml:lang="en"><p>Loskutov Igor A. — MD, head of the Ophthalmology department for adults</p><p>Shchepkina str., 61/2, Moscow, 123007</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirsky Moscow Regional Research Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2024</year></pub-date><volume>21</volume><issue>1</issue><fpage>74</fpage><lpage>81</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абакаров С.А., Лоскутов И.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Абакаров С.А., Лоскутов И.А.</copyright-holder><copyright-holder xml:lang="en">Abakarov S.A., Loskutov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2295">https://www.ophthalmojournal.com/opht/article/view/2295</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить клинические особенности при проникающих ранениях глаза с инородным телом, осложненных развитием эндофтальмита.</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. В ретроспективное исследование были включены 68 человек (68 глаз) с проникающим ранением и инородным телом глаза, из них 91,2 % мужчин и 8,8 % женщин, средний возраст — 50,00 [32,00; 60,00] лет. Пациенты были разделены на 2 группы: с эндофтальмитом — 24 пациента, без эндофтальмита — 44. Всем пациентам проводились стандартные офтальмологических методы обследования.</p></sec><sec><title>Результаты</title><p>Результаты. Возраст пациентов с эндофтальмитом был достоверно больше по сравнению с пациентами без воспаления — 51,50 [46,25; 63,25] года и 36,50 [31,25; 58,50] года соответственно (р = 0,0446). В первые сутки после получения травмы за медицинской помощью обратились лишь 25 % пациентов (p = 0,0071). У пациентов с эндофтальмитом по данным биомикроскопии при поступлении достоверно чаще отмечались отек век (p &lt; 0,0001), гнойное отделяемое (p &lt; 0,0001), тотальная гифема (р = 0,029), гипопион (p &lt; 0,0001), отек радужки (р &lt; 0,0001), наличие фибрина в стекловидном теле (p = 0,0014), а также его деструкция (p = 0,0005). У 87,5 % пациентов с эндофтальмитом отсутствовал рефлекс с глазного дна (p = 0,0105), а у 25 % пациентов с воспалением имело место повышение внутриглазного давления (р = 0,0019). Факоэмульсификация катаракты выполнена в 91,7 % случаев у пациентов с эндофтальмитом (p &lt; 0,0001), в 87,5 % случаев в данной группе потребовалось проведение витрэктомии (p = 0,0098), в 12,5 % — энуклеации глаза (р = 0,0165) и в 12,5 % — эвисцерации (p = 0,0165). Бактериальный посев содержимого из раны у пациентов с эндофтальмитом в 100 % случаев выявил грамположительную микрофлору. Между группами отмечались достоверные различия в применяемой интравитреальной, системной и субконъюнктивальной антибиотикотерапии.</p></sec><sec><title>Заключение</title><p>Заключение. Пациенты с проникающим ранением глаза и инородным телом, осложненным развитием эндофтальмита, характеризуются более тяжелым объективным статусом с признаками воспаления, выраженным повреждением глаза и его структур.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to study the clinical features of patients with penetrating eye injury and foreign body, complicated by endophthalmitis.</p></sec><sec><title>Methods</title><p>Methods. 68 patients (68 eyes) with penetrating injury and ocular foreign body were included in the retrospective study, including 91.2 % males and 8.8 % females. The mean age was 50.00 [32.00; 60.00] years. The patients were divided into 2 groups: with endophthalmitis — 24 patients, without inflammation — 44 patients. All patients underwent standard ophthalmologic methods of examination.</p></sec><sec><title>Results</title><p>Results. The age of patients with endophthalmitis was significantly greater compared to patients without inflammation — 51.50 [46.25; 63.25] years and 36.50 [31.25; 58.50] years, respectively (p = 0.0446). In the first day after injury, only 25 % of patients asked for medical care (p = 0.0071). In patients with endophthalmitis according to biomicroscopy data on admission the following were significantly more frequent: eyelid edema (p &lt; 0.0001), purulent discharge (p &lt; 0.0001), total hyphema (p = 0.029), hypopyon (p &lt; 0.0001), iris edema (p &lt; 0.0001), fibrin in vitreous body (p = 0.0014), as well as its destruction (p = 0.0005). 87.5 % of patients with endophthalmitis showed absence of fundus reflex (p = 0.0105), and 25 % of patients with inflammation showed increased intraocular pressure (p = 0.0019). In patients with endophthalmitis, surgical treatment was performed: cataract phacoemulsification in 91.7 % of patients (p &lt; 0.0001), vitreoectomy in 87.5 % (p = 0.0098), enucleation of the eye in 12.5 % (p = 0.0165) and evisceration in 12.5 % (p = 0.0165). Bacterial culture in patients with endophthalmitis revealed Gram-positive microflora in 100 % of cases. There were also significant differences between the groups in the intravitreal, systemic and subconjunctival antibiotic therapy used.</p></sec><sec><title>Conclusion</title><p>Conclusion. Patients with penetrating eye injury and foreign body, complicated by endophthalmitis, are characterized by more signs of inflammation, pronounced damage to the eye and its structures.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>проникающее ранение глаза</kwd><kwd>инородное тело</kwd><kwd>посттравматический эндофтальмит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>penetrating eye injury</kwd><kwd>foreign body</kwd><kwd>post-traumatic endophthalmitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Попова АА, Гусев АА. Применение витреоретинальной хирургии при лечении проникающего ранения глазного яблока с внутриглазной локализацией инородного тела. Университетская медицина Урала. 2019;5(2(17)):32–34.</mixed-citation><mixed-citation xml:lang="en">Popova AA, Gusev AA. 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