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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-1-152-161</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2305</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Результаты количественной и качественной оценки цветового зрения у пациентов с врожденной частичной атрофией зрительного нерва</article-title><trans-title-group xml:lang="en"><trans-title>Results of Quantitative and Qualitative Assessment of Color Vision in Patients with Congenital Partial Atrophy of the Optic Nerve</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рычкова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Rychkova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рычкова Светлана Игоревна — доктор медицинских наук, врач-офтальмолог, ведущий научный сотрудник лаборатории «Зрительные системы»; доцент кафедры «Глазные болезни»</p><p>Большой Каретный переулок, 19, Москва, 127051, </p><p>ул. Гамалеи, 15, Москва, 123098</p></bio><bio xml:lang="en"><p>Rychkova Svetlana I. — МD, оphthalmologist, leading researcher of the laboratory of the “Visual system”; lecturer of the Department of “Eye diseases”</p><p>Bolshoy Karetny lane, 19, Moscow, 127051, </p><p>Gamalei str., 15, Moscow, 123098</p></bio><email xlink:type="simple">lana.rych@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лихванцева</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Likhvantseva</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лихванцева Вера Геннадьевна — доктор медицинских наук, профессор, профессор кафедры «Офтальмология»</p><p>Волоколамское шоссе, 91, Москва, 125310</p></bio><bio xml:lang="en"><p>Likhvantseva Vera G. — MD, Professor of the Department of ophthalmology</p><p>Volokolamskoe highway, 91, Moscow, 125310</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сандимиров</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sandimirov</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сандимиров Роман Игоревич — студент</p><p>ул. Островитянова, 1, Москва, 117997</p></bio><bio xml:lang="en"><p>Sandimirov Roman I. — student</p><p>Ostrovityanova str., 1 Moscow, 117997</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУН «Институт проблем передачи информации им. А.А. Харкевича» Российской академии наук; &#13;
ФГБУ Государственный научный центр «Федеральный медицинский биофизический центр имени А.И. Бурназяна» Федерального медико-биологического агентства<country>Россия</country></aff><aff xml:lang="en">A.A. Kharkevich Institute for Information Transmission Problems of the Russian Academy of Sciences;&#13;
Medical and Biological University of Innovation and Continuing Education of Russian State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical and Biological Agency<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФПК «Академия постдипломного образования» ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий» Федерального медико-биологического агентства<country>Россия</country></aff><aff xml:lang="en">Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of Federal Medical and Biological Agency of Russia<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">N.I. Pirogov Russian National Research Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2024</year></pub-date><volume>21</volume><issue>1</issue><fpage>152</fpage><lpage>161</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рычкова С.И., Лихванцева В.Г., Сандимиров Р.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Рычкова С.И., Лихванцева В.Г., Сандимиров Р.И.</copyright-holder><copyright-holder xml:lang="en">Rychkova S.I., Likhvantseva V.G., Sandimirov R.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2305">https://www.ophthalmojournal.com/opht/article/view/2305</self-uri><abstract><p>Врожденная частичная атрофия зрительного нерва (ЧАЗН) является одной из основных причин слепоты и слабовидения у пациентов с патологией глазного дна. В диагностике и мониторинге зрительных функций важное значение имеет исследование цветового зрения.</p><p>Цель — разработать собственный способ комплексной диагностики цветового зрения с количественной и качественной оценкой нарушений цветовосприятия и раскрыть его возможности у пациентов с частичной атрофией зрительного нерва.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Под наблюдением находились 55 пациентов в возрасте от 8 до 20 лет с врожденной частичной атрофией зрительного нерва (ЧАЗН) и типичной для данного заболевания картиной глазного дна, характерными показателями ЭФИ. Контрольная группа включала 116 человек того же возраста без патологии глазного дна и с нормальной остротой зрения. Для исследования цветового зрения в обеих группах использовали классический дихотомический тест Фарнсворта — Манселла D-15 (FarnsworthMunsell Dichotomous D15 Test) и разработанный собственный способ количественной и качественной оценки цветового зрения.</p></sec><sec><title>Результаты</title><p>Результаты. Разработанный способ позволил выявить нарушения цветовосприятия разной степени выраженности у большинства (около 90 %) пациентов с ЧАЗН, в то время как более 70 % человек контрольной группы продемонстрировали нормальное цветовосприятие. Количественная оценка цветового зрения при помощи разработанного нами способа показывает достоверно более высокие показатели суммарной ошибки восприятия цветовых тонов у пациентов с ЧАЗН (35,6 ± 3,2 градуса для лучше видящего глаза и 39,9 ± 3,3 градуса для хуже видящего глаза) по сравнению с обследуемыми контрольной группы (6,2 ± 1,1 градуса для лучше видящего глаза и 7,5 ± 1,3 градуса для хуже видящего глаза). Выраженность нарушений цветовосприятия у пациентов с ЧАЗН не зависит от возраста, но имеет достоверную обратную зависимость от остроты зрения. В группе пациентов с ЧАЗН при исследовании как лучше видящего, так и хуже видящего глаза выявляются нарушения восприятия всех цветовых тонов с небольшим преобладанием нарушений восприятия красного, зеленого и синего. Разработанный способ имеет высокую чувствительность и специфичность, сопоставимые с классическим тестом Фарнсворта — Манселла D-15.</p></sec><sec><title>Заключение</title><p>Заключение. Разработанный способ позволяет эффективно осуществлять количественную и качественную оценку цветовосприятия у пациентов с ЧАЗН.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Congenital partial atrophy of the optic nerve is one of the main causes of blindness and low vision in patients with fundus pathology, and the study of color vision is important in diagnosis and monitoring visual functions in patients with this disease.</p></sec><sec><title>Purpose</title><p>Purpose: to study the possibilities of using the own developed method of quantitative and qualitative assessment of color vision in patients with partial optic nerve atrophy.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 55 patients aged from 8 to 20 years with congenital partial atrophy of the optic nerve (PAON) with a typical fundus pattern and EFI indicators for this disease were observed. The control group included 116 people of the same age without fundus pathology and with normal visual acuity. To study color vision in both groups, the classic FarnsworthMunsell Dichotomous D15 Test and the own developed method for quantitative and qualitative assessment of color vision were used.</p></sec><sec><title>Results</title><p>Results. The method developed by us made it possible to identify color perception disorders of varying severity in the majority (about 90 %) of patients with PAON. In the control group, no color perception disorders were detected in more than 70 % of the subjects. Quantitative assessment of color vision conducted using the method developed by us demonstrates significantly higher indicators of the total error of perception of color tones in patients with PAON (35.6 ± 3.2 degrees for a better-seeing eye and 39.9 ± 3.3 degrees for a worse-seeing eye) in comparison with the subjects of the control group (6.2 ± 1.1 degrees for a better-seeing eye and 7.5 ± 1.3 degrees for a worse-seeing eye). The severity of color perception disorders in patients with PAON does not depend on age, but has a significant inverse relationship with visual acuity. In the group of patients with PAON, when examining both better-seeing eye and worse-seeing eye, perception disorders of all color tones are detected with a slight predominance of disorders of perception of red, green and blue. The method developed by us has sufficiently higher sensitivity and specificity in comparison with the classic Farnsworth-Mansell D-15 test.</p></sec><sec><title>Conclusion</title><p>Conclusion. The method developed by us makes it possible to effectively carry out a quantitative and qualitative assessment of the state of color perception in patients with PAON.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>частичная атрофия зрительного нерва</kwd><kwd>цветовое зрение</kwd><kwd>методы диагностики цветового зрения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>partial atrophy of the optic nerve</kwd><kwd>color vision</kwd><kwd>diagnostic methods of color vision</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Федорова СН, Белова ОВ. Структура и причины врожденных атрофий зрительного нерва в Хабаровском крае. Вестник Оренбургского государственного университета. 2004;S(38):225–227.</mixed-citation><mixed-citation xml:lang="en">Fedorova SN, Belova OV. Structure and causes of congenital atrophy of the optic nerve in the Khabarovsk territory. 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