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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-2-341-347</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2370</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Изучение влияния различных методов интраоперационной кератопротекции на морфофункциональное состояние структур глазной поверхности в ранние сроки после факоэмульсификации возрастной катаракты</article-title><trans-title-group xml:lang="en"><trans-title>Study of Influence of Various Methods of Intraoperative Keratoprotection  on Morphological and Functional State of Ocular Surface System in Early Period after Phacoemulsification in Senile Cataract</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6514-7236</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тонконогий</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tonkonogiy</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тонконогий Сергей Викторович врач‑офтальмолог 1‑го офтальмологического отделения</p><p>ул. Тихоокеанская, 211, Хабаровск, 680033</p><p> </p></bio><bio xml:lang="en"><p>Tonkonogiy Sergei V., ophthalmologist of the 1st Ophthalmological Department</p><p>Tikhookeanskaya str., 211, Khabarovsk, 680033</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7501-5571</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коленко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коленко Олег Владимирович, доктор медицинских наук, директор Хабаровского филиала;  заведующий кафедрой офтальмологии Института повышения квалификации; профессор кафедры общей и клинической хирургии Дальневосточного медицинского университета</p><p>ул. Тихоокеанская, 211, Хабаровск, 680033</p><p>ул. Краснодарская, 9, Хабаровск, 680000</p><p>ул. Муравьева‑Амурского, 35, Хабаровск, 680000</p></bio><bio xml:lang="en"><p>Kolenko Oleg V., MD, head; chief of the Ophthalmology Department;  Professor of the General and Clinical Surgery Department</p><p>Tikhookeanskaya str., 211, Khabarovsk, 680033</p><p>Krasnodarskaya str., 9, Khabarovsk, 680000</p><p>Murav’yeva‑Amurskogo str., 35, Khabarovsk, 680000</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9712-0276</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasiliev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Алексей Владимирович, кандидат медицинских наук, заведующий 1‑м офтальмологическим отделением, врач‑офтальмолог</p><p>ул. Тихоокеанская, 211, Хабаровск, 680033</p></bio><bio xml:lang="en"><p>Vasiliev Alexey V., PhD, chief of the 1st Ophthalmological Department, ophthalmologist</p><p>Tikhookeanskaya str., 211, Khabarovsk, 680033</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Хабаровский филиал ФГАУ НМИЦ «МНТК “Микрохирургия глаза”  им. академика С.Н. Федорова» Министерства здравоохранения  &#13;
Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Khabarovsk Branch of the S. Fyodorov Eye Microsurgery  Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Хабаровский филиал ФГАУ НМИЦ «МНТК “Микрохирургия глаза”  им. академика С.Н. Федорова» Министерства здравоохранения Российской Федерации; КГБОУ ДПО «Институт повышения квалификации специалистов здравоохранения» Министерства здравоохранения Хабаровского края; ФГБОУ ВО «Дальневосточный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Khabarovsk Branch of the S. Fyodorov Eye Microsurgery Federal State Institution; Postgraduate Institute for Public Health Workers; Far Eastern State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2024</year></pub-date><volume>21</volume><issue>2</issue><fpage>341</fpage><lpage>347</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тонконогий С.В., Коленко О.В., Васильев А.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Тонконогий С.В., Коленко О.В., Васильев А.В.</copyright-holder><copyright-holder xml:lang="en">Tonkonogiy S.V., Kolenko O.V., Vasiliev A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2370">https://www.ophthalmojournal.com/opht/article/view/2370</self-uri><abstract><p>Цель — изучить влияние различных методов интраоперационной кератопротекции на морфофункциональное состояние структур глазной поверхности (СГП) в ранние сроки после факоэмульсификации возрастной катаракты (ФЭ ВК). Пациенты и методы. 240 пациентов (240 глаз) в возрасте 65 ± 4 года, 109 мужчин, 131 женщина обратились для оперативного лечения ВК. Все пациенты по методу интраоперационной кератопротекции были разделены на три группы наблюдения: 1-я группа — 60 пациентов, орошение роговицы сбалансированным раствором; 2-я группа — 60 пациентов, на роговицу накладывали вискоэластик; 3-я группа: 3а подгруппа — 60 пациентов, на роговицу накладывали мягкую контактную линзу (МКЛ); 3б подгруппа — 60 пациентов, на роговицу накладывали МКЛ, пропитанную раствором рибофлавина. Кроме стандартного офтальмологического обследования проводили тест Ширмера-I, ОКТ-сканирование, определяли время разрыва слезной пленки (ВРСП). Результаты. Операции были выполнены без осложнений. В 1-е сутки после операции показатели пробы Ширмера оказались выше в глазах 1-й и 2-й групп. На 5-е сутки после операции слезопродукция резко снизилась во всех глазах. На 10-е сутки увеличение слезопродукции наблюдалось во всех группах, максимальный прирост — в 3б подгруппе. В 1-е сутки после операции ВРСП снизилось во всех исследуемых глазах. Наибольшее значимое снижение ВРСП было отмечено в 1-й группе, наименьшее — в 3б подгруппе. В 1-е сутки толщина эпителия роговицы (ТЭР) снизилась во всех глазах, максимальное снижение выявлено в 1-й группе. На 5 сутки ТЭР продолжала снижаться во всех глазах, минимальное снижение произошло в 3б подгруппе. На 10-е сутки отмечено уменьшение ТЭР во всех группах с минимальной значимой динамикой в 3б подгруппе. Заключение. Проведенное исследование показало, что состояние СГП в раннем периоде после ФЭ ВК зависит от метода интраоперационной кератопротекции. Наиболее оптимальным методом интраоперационной защиты эпителия роговицы и профилактики негативного морфофункционального состояния СГП после ФЭ ВК является применение МКЛ, пропитанной рибофлавином.</p></abstract><trans-abstract xml:lang="en"><p>Purpose: to study the effect of various methods of intraoperative keratoprotection on morphological and functional state of ocularsurface system (OSS) in early period after phacoemulsification (PE) in senile cataract (SC). Patients and methods. 240 patients (240 eyes) who applied for surgical treatment of SC. Age: 65 ± 4 years. 109 men, 131 women. All patients were divided into three observation groups according to the method of intraoperative keratoprotection: 1st group — 60 patients, corneal irrigation with balanced solution; 2nd group — 60 patients, ophthalmic viscosurgical device was applied to the cornea; 3rd group: 3a subgroup — 60 patients, soft contact lens (SCL) was applied to the cornea; subgroup 3b — 60 patients, SCL impregnated with riboflavin solution was applied to the cornea. In addition to the standard ophthalmological examination, Schirmer I test, OCT-scanning were performed, and tear breakup time (TBUT) was determined. Results. Operations were performed without complications. On the 1st day after the operation, the parameters of the Schirmer I test were higher in the eyes of 1st and 2nd groups. On the 5th day after the operation, tear production decreased sharply in all eyes. On the 10th day, an increase in tear production was observed in all groups, the maximum increase — in 3b subgroup. On the 1st day after the operation, TBUT decreased in all examined eyes. The largest significant TBUT decrease was noted in 1st group, the smallest — in 3b subgroup. On 1st day, corneal epithelial thickness (CET) decreased in all eyes, the maximum decrease was detected in 1st group. On the 5th day, CET continued to decrease in all eyes, the minimum decrease occurred in the 3b subgroup. On the 10th day — a decrease in CET in all groups with minimal significant dynamics in 3b subgroup. Conclusion. The study showed that the state of OSS in the early period after PE in SC depends on the method of intraoperative keratoprotection. The most optimal method of intraoperative protection of corneal epithelium and prevention of negative morphological and functional state of OSS after PE in SC is using of SCL impregnated with riboflavin.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная катаракта</kwd><kwd>слезопродукция</kwd><kwd>синдром сухого глаза</kwd><kwd>факоэмульсификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>senile cataract</kwd><kwd>tear production</kwd><kwd>dry eye syndrome</kwd><kwd>phacoemulsification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ерёменко А.И., Бойко А.А., Янченко С.В., Дубинкина В.О., Куликова О.В. Профилактика комбинированного синдрома сухого глаза у пациентов старшей возрастной группы после катарактальной хирургии. 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