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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-3-612-616</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2443</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEALTH CARE</subject></subj-group></article-categories><title-group><article-title>Превалентность оперированных лиц со старческой катарактой на неоднородных биотехногенных территориях</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of Operated Persons with Senile Cataracts in Heterogeneous Biotechnogenic Territories</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюнина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyunina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тюнина Наталья Владимировна - заместитель главного врача по офтальмологической помощи.</p><p>Октябрьский пр., 22, Кемерово, 650061</p></bio><bio xml:lang="en"><p>Tyunina Natalya V. - MD, chief for Ophthalmological Care.</p><p>Oktyabrsky Ave., 22, Kemerovo, 650061</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громакина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromakina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громакина Елена Владимировна - доктор медицинских наук, профессор, заведующая кафедрой офтальмологии.</p><p>Ул. Ворошилова, 22а, Кемерово, 650056</p></bio><bio xml:lang="en"><p>Gromakina Elena V. - MD, Professor, head of the Department of Ophthalmology.</p><p>Voroshilova str., 22A, Kemerovo, 650056</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Басова</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Basova</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Басова Галина Григорьевна - кандидат медицинских наук, доцент кафедры офтальмологии.</p><p>Ул. Ворошилова, 22а, Кемерово, 650056</p></bio><bio xml:lang="en"><p>Basova Galina G. - PhD, Associate Professor of the Department of Ophthalmology.</p><p> Voroshilova str., 22A, Kemerovo, 650056</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мозес</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Moses</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мозес Вадим Гельевич - доктор медицинских наук, профессор, директор.</p><p>Красная ул., 6, Кемерово, 650000</p></bio><bio xml:lang="en"><p>Moses Vadim G. - MD, Professor, rector of the Medical Institute.</p><p>Krasnaya str., 6, Kemerovo, 650000</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГАУЗ КО «Кузбасская областная клиническая больница имени С.В. Беляева» Министерство здравоохранения Кузбасса</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuzbass Clinical Hospital, Ministry of Kuzbass Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кемеровский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo State Medical University, Ministry of Kuzbass Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кемеровский государственный университет» Министерство здравоохранения Кузбасса</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>03</day><month>10</month><year>2024</year></pub-date><volume>21</volume><issue>3</issue><fpage>612</fpage><lpage>616</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тюнина Н.В., Громакина Е.В., Басова Г.Г., Мозес В.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Тюнина Н.В., Громакина Е.В., Басова Г.Г., Мозес В.Г.</copyright-holder><copyright-holder xml:lang="en">Tyunina N.V., Gromakina E.V., Basova G.G., Moses V.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2443">https://www.ophthalmojournal.com/opht/article/view/2443</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: проанализировать влияние уровня техногенной нагрузки на частоту хирургического лечения и возрастной статус лиц со старческой катарактой, проживающих на различных территориях Кемеровской области — Кузбасса.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. С 2015 по 2019 год в условиях круглосуточного пребывания в стационаре оперированы по поводу возрастной катаракты 228 372 пациента из 7 городов и районов с высоким уровнем техногенной нагрузки и из 6 городов с низким уровнем техногенной нагрузки.</p></sec><sec><title>Результаты</title><p>Результаты. Абсолютное количество оперированных лиц было больше на территориях с высоким уровнем техногенной нагрузки по сравнению с территориями с низким уровнем техногенной нагрузки (187 876 против 40 496) и в среднем превышало ежегодно в 4,6 раза (37 575 против 8099). Количество оперированных лиц с учетом динамики численности населения за счет убыли и рождаемости на различных территориях по годам имело колебания на 10 000 населения и превышало на территориях с высоким уровнем техногенной нагрузки в среднем на 27,0 %. Средний возраст оперированных лиц с катарактой мало отличался в популяциях с высоким и низким уровнями техногенной нагрузки. Однако на территориях с высоким уровнем оперированных лиц в возрасте 51–60 лет было в 2,5 раза больше.</p></sec><sec><title>Выводы</title><p>Выводы. Количество оперированных лиц со старческой катарактой за пятилетний период на 10 000 населения составило в среднем 176,46 на территории с высоким уровнем техногенной нагрузки и 134,14 — с низким уровнем, с числовым преимуществом по десятилетиям от 9,67 до 45,47 %, (среднегодовой показатель 27,0 %). Оперированных пациентов с возрастной катарактой в возрасте 51– 60 лет было в 2,5 раза больше (4,9 % против 1,9 %) на территориях с высоким уровнем техногенной нагрузки по сравнению с низким уровнем при среднем возрасте 72,02 ± 8,32 и 71,04 ± 10,11 года соответственно.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose of the study</title><p>Purpose of the study: to evaluate the influence of the level of anthropogenic load on the frequency of surgical treatment and age status of people with senile cataracts living in various territories of the Kemerovo region — Kuzbass.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. From 2015 to 2019, 228 372 patients from 7 cities and regions with a high level of technogenic load and from 6 cities with a low level of technogenic load were operated on for age-related cataracts in a 24-hour hospital stay.</p></sec><sec><title>Results</title><p>Results. The absolute number of operated persons was greater in territories with a high level of technogenic load compared to a low level of technogenic load (187 876 versus 40496) and on average exceeded 4.6 times annually (37 575 versus 8099). The number of operated persons, taking into account the dynamics of the population due to decline and birth rates in different territories over the years, fluctuated per 10 000 population, and exceeded in territories with a high level of technogenic load by an average of 27.0 %. The average age of operated patients with cataracts differed little in populations with high and low levels of technogenic load. However, in territories with a high level of technogenic load compared to a low level of technogenic load, there were 2.5 times more operated people aged 51–60 years.</p></sec><sec><title>Conclusions</title><p>Conclusions. The number of operated people with senile cataracts over a five-year period per 10 000 population averaged 176.46 in areas with a high level of technogenic load and 134.14 with a low level, with a numerical advantage over decades from 9.67 % to 45.47 %, (annual average 27.0 %). There were 2.5 times more operated patients with age-related cataracts aged 51–60 years (4.9 % versus 1.9 %) in areas with a high level of technogenic load compared to a low level, with an average age of 72.02 ± 8.32 and 71.04 ± 10.11 years, respectively.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная катаракта</kwd><kwd>хирургическое лечение</kwd><kwd>демография</kwd><kwd>уровень техногенной нагрузки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>age-related cataract</kwd><kwd>surgical treatment</kwd><kwd>demographics</kwd><kwd>level of anthropogenic load</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Purola PKM, Nättinen JE, Ojamo MUI, Rissanen HA, Gissler M, Koskinen SVP, Uusitalo HMT. Prevalence and 11‑Year Incidence of Cataract and Cataract Surgery and the Effects of Socio‑Demographic and Lifestyle Factors. Clin Ophthalmol. 2022 Apr 20;16:1183–1195. doi: 10.2147/OPTH.S355191.</mixed-citation><mixed-citation xml:lang="en">Purola PKM, Nättinen JE, Ojamo MUI, Rissanen HA, Gissler M, Koskinen SVP, Uusitalo HMT. Prevalence and 11‑Year Incidence of Cataract and Cataract Surgery and the Effects of Socio‑Demographic and Lifestyle Factors. Clin Ophthalmol. 2022 Apr 20;16:1183–1195. doi: 10.2147/OPTH.S355191.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Liu FY, Fu JL, Wang L, Nie Q, Luo Z, Hou M, Yang Y, Gong XD, Wang Y, Xiao Y, Xiang J, Hu X, Zhang L, Wu M, Chen W, Cheng B, Luo L, Zhang X, Liu X, Zheng D, Huang S, Liu Y, Li DW. Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. Aging Cell. 2020 Oct;19(10):e13222. doi: 10.1111/acel.13222.</mixed-citation><mixed-citation xml:lang="en">Liu FY, Fu JL, Wang L, Nie Q, Luo Z, Hou M, Yang Y, Gong XD, Wang Y, Xiao Y, Xiang J, Hu X, Zhang L, Wu M, Chen W, Cheng B, Luo L, Zhang X, Liu X, Zheng D, Huang S, Liu Y, Li DW. Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. Aging Cell. 2020 Oct;19(10):e13222. doi: 10.1111/acel.13222.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cantrell LS, Schey KL. Proteomic characterization of the human lens and Cataractogenesis. Expert Rev Proteomics. 2021 Feb;18(2):119–135. doi: 10.1080/14789450.2021.1913062.</mixed-citation><mixed-citation xml:lang="en">Cantrell LS, Schey KL. Proteomic characterization of the human lens and Cataractogenesis. Expert Rev Proteomics. 2021 Feb;18(2):119–135. doi: 10.1080/14789450.2021.1913062.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Киселева ТН, Зайцев МС. Современные представления о молекулярных механизмах возрастных изменений хрусталика. Офтальмология. 2023;20(3): 384–389. doi: 10.18008/1816‑5095‑2023‑3‑384‑389.</mixed-citation><mixed-citation xml:lang="en">Kiseleva TN, Zaitsev MS. Current Concepts of Molecular Mechanisms of Age‑Related Changes in Eye Lens. Ophthalmology in Russia. 2023;20(3):384–389 (In Russ.). doi: 10.18008/1816‑5095‑2023‑3‑384‑389.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Truscott RJ, Friedrich MG. The etiology of human age‑related cataract. Proteins don’t last forever. Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):192–8. doi: 10.1016/j.bbagen.2015.08.016.</mixed-citation><mixed-citation xml:lang="en">Truscott RJ, Friedrich MG. The etiology of human age‑related cataract. Proteins don’t last forever. Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):192–8. doi: 10.1016/j.bbagen.2015.08.016.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Schey KL, Wang Z, Friedrich MG, Truscott RJW. New insights into the mechanisms of age‑related protein‑protein crosslinking in the human lens. Exp Eye Res. 2021 Aug;209:108679. doi: 10.1016/j.exer.2021.108679.</mixed-citation><mixed-citation xml:lang="en">Schey KL, Wang Z, Friedrich MG, Truscott RJW. New insights into the mechanisms of age‑related protein‑protein crosslinking in the human lens. Exp Eye Res. 2021 Aug;209:108679. doi: 10.1016/j.exer.2021.108679.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Truscott RJW, Friedrich MG. Molecular Processes Implicated in Human Age‑Related Nuclear Cataract. Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):5007–5021. doi: 10.1167/iovs.19‑27535.</mixed-citation><mixed-citation xml:lang="en">Truscott RJW, Friedrich MG. Molecular Processes Implicated in Human Age‑Related Nuclear Cataract. Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):5007–5021. doi: 10.1167/iovs.19‑27535.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Karimi S, Arabi A, Shahraki T. Alcohol and the Eye. J Ophthalmic Vis Res. 2021 Apr 29;16(2):260–270. doi: 10.18502/jovr.v16i2.9089.</mixed-citation><mixed-citation xml:lang="en">Karimi S, Arabi A, Shahraki T. Alcohol and the Eye. J Ophthalmic Vis Res. 2021 Apr 29;16(2):260–270. doi: 10.18502/jovr.v16i2.9089.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Nieder R, Benbi DK. Reactive nitrogen compounds and their influence on human health: an overview. Rev Environ Health. 2021 May 24;37(2):229–246. doi: 10.1515/reveh‑2021‑0021.</mixed-citation><mixed-citation xml:lang="en">Nieder R, Benbi DK. Reactive nitrogen compounds and their influence on human health: an overview. Rev Environ Health. 2021 May 24;37(2):229–246. doi: 10.1515/reveh‑2021‑0021.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Тахауова ЛР, Кривошеина ОИ. Оценка заболеваемости глазной поверхности у персонала объекта использования атомной энергии. Современные технологии в офтальмологии. 2023:6(52):128–133. doi: 10.25276/2312‑4911‑2023‑6‑128‑133.</mixed-citation><mixed-citation xml:lang="en">Takhauova LR, Krivosheina OI. Assessment of ocular surface morbidity among personnel of a nuclear energy facility. Modern technologies in ophthalmology. 2023:6(52):128–133 (In Russ.). doi: 10.25276/2312‑4911‑2023‑6‑128‑133.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Аксёненко АВ, Громакина ЕВ. Нозологическая структура заболеваний органа зрения у работников с вредными условиями труда. Обзор. Офтальмология. 2022;19(1):202–209.</mixed-citation><mixed-citation xml:lang="en">Aksyonenko AV, Gromakina EV. The Nosological Structure of Eye’s Diseases in Workers with Harmful Working Condition. Review. Ophthalmology in Russia. 2022;19(1):202–209 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Сусликов ВЛ, Андреев АН, Степанов РВ, Мадианов ИВ. К вопросу о роли биогеохимических факторов в патогенезе возрастной катаракты. Офтальмологический журнал. 1990;(5):296‑299</mixed-citation><mixed-citation xml:lang="en">Suslikov VL, Andreev AN, Stepanov RV, Madianov IV. The role of biogeochemical factors in the pathogenesis of age‑related cataract. Oftalmol Zh. 1990;(5):296–299 (In Russ.). PMID: 1965226.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
