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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2024-4-650-657</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2486</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Оптическая когерентная томография в диагностике первичной открытоугольной глаукомы</article-title><trans-title-group xml:lang="en"><trans-title>Optical Coherence Tomography in the Diagnosis of Open-angle Glaucoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4043-456X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсеф</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusef</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юсеф Наим Юсеф, доктор медицинских наук, директор</p><p>ул. Россолимо, 11а, б, Москва, 119021</p></bio><bio xml:lang="en"><p>Yusef Naim Y., MD, Head of Research Institute of Eye Diseases</p><p>Rossolimo str., 11A, B, Moscow, 119021</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0391-4695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казарян</surname><given-names>Э. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazaryan</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казарян Элина Эдуардовна, доктор медицинских наук, старший научный сотрудник отдела современных методов лечения в офтальмологии</p><p>ул. Россолимо, 11а, б, Москва, 119021</p></bio><bio xml:lang="en"><p>Kazaryan Elina E., MD, Senior Research Officer of the Modern Treatment Methods in Ophthalmology Department</p><p>Rossolimo str., 11A, B, Moscow, 119021</p></bio><email xlink:type="simple">elina-kazaryan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт глазных болезней имени М.М. Краснова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.M. Krasnov Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>12</month><year>2024</year></pub-date><volume>21</volume><issue>4</issue><fpage>650</fpage><lpage>657</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юсеф Ю.Н., Казарян Э.Э., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Юсеф Ю.Н., Казарян Э.Э.</copyright-holder><copyright-holder xml:lang="en">Yusef Y.N., Kazaryan E.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2486">https://www.ophthalmojournal.com/opht/article/view/2486</self-uri><abstract><p>Обзор литературы содержит сведения о возможностях и роли ОКТ-А в диагностике первичной открытоугольной глаукомы (ПОУГ). Необходимость в методах неинвазивной оценки глазной сосудистой сети привела к разработке ОКТ-ангиографии (ОКТ-А), которая обеспечивает предоставление информации о состоянии как структуры сетчатки, так и ее сосудистого русла путем анализа кровотока, что еще больше повышает ценность этого метода визуализации по сравнению с обычной ОКТ. Оценка кровотока с помощью OCT-A может использоваться для выявления многих сосудистых нарушений сетчатки, таких как определение области отсутствия перфузии, нефункционирующие сосуды, появление новых сосудов в областях, которые являются аваскулярными, увеличение васкуляризации, наличие микро- и макроаневризм, ремоделирование капилляров, макулярная телеангиэктазия и венозные мальформации. ОКТ-А является неинвазивным средством визуализации ретинальной и хориоидальной сосудистой сети, обеспечивая уникальное представление о сосудистой системе, которое можно объединить с данными, полученными от других методов визуализации, для дополнения и со временем предоставления уникальной информации, помогающей врачу-офтальмологу в отношении диагностики или эффективности вмешательства. Параметры OCT-A определяют в перипапиллярной области, мониторинг плотности перипапиллярных и макулярных сосудов может представить важную информацию для оценки прогрессирования ПОУГ и прогнозирования темпов ухудшения заболевания. Исследования показывают наличие сильной корреляционной связи между параметрами ОКТ и зрительными функциями при ПОУГ. В перспективе применение ОКТ-А в диагностике глаукомы с использованием искусственного интеллекта с прогнозированием структурных и функциональных особенностей на основе определения ранних сосудистых изменений обеспечит возможности для раннего выявления пациентов с высоким риском появления и быстрого прогрессирования глаукомы. Потенциально ОКТ-А может стать частью диагностики глаукомы.</p></abstract><trans-abstract xml:lang="en"><p>This literature review provides information on the capabilities and role of OCT-A in the diagnosis of open-angle glaucoma. The need for non-invasive methods of assessing the ocular vasculature has led to the development of OCT-angiography (OCT-A), which provides information on the state of both the retinal structure and its vascular bed through blood flow analysis, further increasing the value of this imaging method compared to conventional OCT. Blood flow assessment with OCT-A can be used to detect many retinal vascular abnormalities, such as the definition of areas of non-perfusion, non-functioning vessels, the appearance of new vessels in areas that are avascular, increased vascularity, the presence of micro- and macroaneurysms, capillary remodeling, macular telangiectasia, and venous malformations. OCT-A is a non-invasive imaging tool for the retinal and choroidal vasculature, providing a unique view of the vascular system that can be combined with information from other imaging modalities to complement and eventually provide unique information to assist the eye care practitioner in diagnosing or evaluating the effectiveness of interventions. OCT-A parameters are measured in the peripapillary region, and monitoring peripapillary and macular vessel density can provide important information to assess glaucoma progression and predict the rate of disease worsening. Studies show a strong correlation between OCT parameters, OCT parameters, and visual function as measured by visual field analysis in glaucomatous eyes. Future prospects for OCT-A in glaucoma diagnostics using artificial intelligence to predict structural and functional features based on early vascular changes will provide opportunities for early identification of patients at high risk for developing and rapidly progressing glaucoma. OCT-A has the potential to become part of glaucoma diagnostics and treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>глаукома</kwd><kwd>ОКТ-А</kwd><kwd>сосудистая сеть</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glaucoma</kwd><kwd>OCT-A</kwd><kwd>vascular network</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Huang D, Swanson EA, LinCP Optical coherencetomography. 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