<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-1-63-68</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2579</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOSURGERY</subject></subj-group></article-categories><title-group><article-title>Реактивация шунтов в хирургии глаукомы</article-title><trans-title-group xml:lang="en"><trans-title>Reactivation of Shunts in Glaucoma Surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6147-5593</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расческов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rascheskov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Расческов Александр Юрьевич, кандидат медицинских наук, главный врач</p><p>ул. Патриса Лумумбы, 28а, Казань, 420000</p></bio><bio xml:lang="en"><p>Rascheskov Alexandr Yu., PhD, chief physician</p><p>Patrisa Lumumbi str., 28A, Kazan, 420000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0888-8281</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расческов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rascheskov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Расческов Арсений Александрович, врач-офтальмолог</p><p>ул. Патриса Лумумбы, 28а, Казань, 420000</p></bio><bio xml:lang="en"><p>Rascheskov Arsenii A., ophthalmologist</p><p>Patrisa Lumumbi str., 28A, Kazan, 420000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0057-3338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лоскутов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Loskoutov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лоскутов Игорь Арсеньевич, доктор медицинских наук, заведующий кафедрой офтальмологии и оптометрии главный внештатный специалист-офтальмолог</p><p>ул. Щепкина, 61/2, Москва, 129110</p><p>бульвар Строителей, 1, Московская область, Красногорск, 143407</p></bio><bio xml:lang="en"><p>Loskoutov Igor A., MD, head of the of Ophthalmology and Optometry Academic Department, chief external specialist for ophthalmology</p><p>Shepkina str., 61/2, Moscow, 129110</p><p>Stroiteley blvd., 1, Karsnogorsk, Moscow Region, 143407</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «Глазная хирургия Расческов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Glaznaya Khirurgiya Rascheskov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»; Министерство здравоохранения Московской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Ministry of Healthcare of the Moscow Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2025</year></pub-date><volume>22</volume><issue>1</issue><fpage>63</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Расческов А.Ю., Расческов А.А., Лоскутов И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Расческов А.Ю., Расческов А.А., Лоскутов И.А.</copyright-holder><copyright-holder xml:lang="en">Rascheskov A.Y., Rascheskov A.A., Loskoutov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2579">https://www.ophthalmojournal.com/opht/article/view/2579</self-uri><abstract><p>Цель: описание основных способов реактивации и сохранения активности шунтовых систем (клапанный дренаж Ахмеда, шунт PRESERFLO) при снижении эффективности их работы на раннем или позднем послеоперационном сроке наблюдения в связи с пролиферативными изменениями в зоне фильтрации.Методы. Экспериментальное исследование, включающее 10 глаз (10 пациентов). После имплантации PRESERFLO в 2-х случаях был проведен нидлинг с введением дексаметазона в область фильтрационной подушки, в 3-х случаях — открытая пластика фильтрационной подушки с очисткой дистального конца трубки от фиброзной ткани и обработкой поля митомицином, в 2-х случаях — реимплантация шунта в другой сектор глаза. В случае шунта Ахмеда во всех 3-х случаях проводилась открытая пластика фильтрационной подушки с иссечением плотной фиброваскулярной мембраны вокруг корпуса клапана.Результаты. Вследствие хирургической реактивации работы шунтов во всех случаях удалось достичь компенсации ВГД в раннем послеоперационном периоде.Заключение. Использование шунтов из современных полимеров для создания дренажной системы глаза позволяет уменьшить зарастание вновь созданных путей оттока ВГЖ, но не решает проблему полностью. Реактивация функционирования шунтов является рутинным видом хирургического лечения глаукомы. В данной статье представлены основные способы реактивации и профилактики нарушения работы шунтов Ахмеда и PRESERFLO.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to present the main methods of reactivation and maintaining the activity of shunt systems (Ahmed valve drainage, PRESERFLO shunts) in cases of reducing the effectiveness of their work in the early or late postoperative follow-up due to proliferative changes in the filtration zone.Methods: an experimental study involving, n = 10 eyes (10 patients). After PRESERFLO implantation: patients underwent needling with dexamethasone injection into the area of the filtration bleb in 2 cases, open plastic surgery of the filtration bleb with cleaning of the distal end of the tube from fibrous tissue and treatment of the filtration area with mitomycin in 3 cases, and reimplantation of the shunt into another sector of the eye in 2 cases. In the case of the Ahmed shunt, in all 3 cases, an open plastic surgery of filtration bleb was performed with excision of a dense fibrovascular membrane around the shunt body.Results. As a result of surgical reactivation of the shunts, compensation of IOP in the early postoperative period was achieved in all cases.Conclusion. The use of shunts made of modern polymers to create an alternative drainage system has reduced the problem of tissue proliferation response on newly created aqueous humor outflow paths, but has not completely solved it. Reactivation of shunts is a routine type of surgical treatment for glaucoma. This article presents the main methods to reactivate and prevent malfunction of the Ahmed and PRESERFLO shunts.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>глаукома</kwd><kwd>шунт</kwd><kwd>Ахмед</kwd><kwd>PRESERFLO</kwd><kwd>реактивация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glaucoma</kwd><kwd>shunt</kwd><kwd>Ahmed</kwd><kwd>PRESERFLO</kwd><kwd>reactivation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition. Br J Ophthalmol. 2021;105:1–169. doi: 10.1136/bjophthalmol-2021-egsguidelines.</mixed-citation><mixed-citation xml:lang="en">European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition. Br J Ophthalmol. 2021;105:1–169. doi: 10.1136/bjophthalmol-2021-egsguidelines.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ang BCH, Lim SY, Betzler BK, Wong HJ, Stewart MW, Dorairaj S. Recent Advancements in Glaucoma Surgery—A Review. Bioengineering. 2023;10:1096. doi: 10.3390/bioengineering10091096.</mixed-citation><mixed-citation xml:lang="en">Ang BCH, Lim SY, Betzler BK, Wong HJ, Stewart MW, Dorairaj S. Recent Advancements in Glaucoma Surgery—A Review. Bioengineering. 2023;10:1096. doi: 10.3390/bioengineering10091096.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL, Tube versus Trabeculectomy Study Group. Treatment outcomes in the Tube Versus Trabeculectomy [TVT] study after five years of follow-up. Am J Ophthalmol. 2012;153:789–803. e2. doi: 10.1016/j.ajo.2011.10.026.</mixed-citation><mixed-citation xml:lang="en">Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL, Tube versus Trabeculectomy Study Group. Treatment outcomes in the Tube Versus Trabeculectomy [TVT] study after five years of follow-up. Am J Ophthalmol. 2012;153:789–803. e2. doi: 10.1016/j.ajo.2011.10.026.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Batlle JF, Corona A, Albuquerque R. Long-term Results of the PRESERFLO MicroShunt in Patients With Primary Open-angle Glaucoma From a Single-center Nonrandomized Study. J Glaucoma. 2021;30:281–286. doi: 10.1097/IJG.0000000000001734.</mixed-citation><mixed-citation xml:lang="en">Batlle JF, Corona A, Albuquerque R. Long-term Results of the PRESERFLO MicroShunt in Patients With Primary Open-angle Glaucoma From a Single-center Nonrandomized Study. J Glaucoma. 2021;30:281–286. doi: 10.1097/IJG.0000000000001734.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Strzalkowska A, Strzalkowski P, Hoffmann EM, Pfeiffer N, Schuster AK. Outcomes of Open Bleb Revision After PreserFlo MicroShunt Failure in Patients With Glaucoma. J Glaucoma. 2023;32:681–685. doi: 10.1097/IJG.0000000000002246.</mixed-citation><mixed-citation xml:lang="en">Strzalkowska A, Strzalkowski P, Hoffmann EM, Pfeiffer N, Schuster AK. Outcomes of Open Bleb Revision After PreserFlo MicroShunt Failure in Patients With Glaucoma. J Glaucoma. 2023;32:681–685. doi: 10.1097/IJG.0000000000002246.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Витков АА, Куроедов АВ, Макарова АС, Полева РП, Дорофеев ДА, Асиновскова ИИ. Повторная хирургия глаукомы: современный взгляд на проблему. Национальный журнал Глаукома. 2023;22(4):80–88. doi: 10.53432/2078-4104-2023-22-4-80-88.</mixed-citation><mixed-citation xml:lang="en">Vitkov AA, Kuroyedov AV, Makarova AS, Poleva RP, Dorofeev DA, Asinovskova II. Repeat glaucoma surgery: modern view of the problem. National Journal glaucoma. 2023;22(4):80–88 (In Russ.). doi: 10.53432/2078-4104-2023-22-4-80-88.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gedde SJ. Results from the Tube Versus Trabeculectomy Study. Middle East Afr J Ophthalmol. 2009;16:107–111. doi: 10.4103/0974-9233.56219.</mixed-citation><mixed-citation xml:lang="en">Gedde SJ. Results from the Tube Versus Trabeculectomy Study. Middle East Afr J Ophthalmol. 2009;16:107–111. doi: 10.4103/0974-9233.56219.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Расческов АЮ. Способ профилактики рубцевания фильтрационной подушки при проведении антиглаукоматозных операций с имплантацией дренажа клапанного типа Ahmed. Патент RU 2802556, 30.08.2023</mixed-citation><mixed-citation xml:lang="en">Rascheskov AYu. Method of preventing scarring of the filtration bleb during antiglaucomatous surgery with implantation of valve-type drainage Ahmed. Patent RU 2802556, 08.30.2023 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Smith M, Geffen N, Alasbali T, Buys YM, Trope GE. Digital ocular massage for hypertensive phase after Ahmed valve surgery. J Glaucoma. 2010;19:11–14. doi: 10.1097/IJG.0b013e31819c485b.</mixed-citation><mixed-citation xml:lang="en">Smith M, Geffen N, Alasbali T, Buys YM, Trope GE. Digital ocular massage for hypertensive phase after Ahmed valve surgery. J Glaucoma. 2010;19:11–14. doi: 10.1097/IJG.0b013e31819c485b.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Петров СЮ. Нидлинг как метод активации фильтрационных подушек: показания, особенности техники. Глаукома. 2013;2:75–84.</mixed-citation><mixed-citation xml:lang="en">Petrov SYu. Needling as a method of activating filtration pads: indications, technical features. Glaucoma. 2013;2:75–84. (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
