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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-1-207-214</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2601</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Трансплантация десцеметовой мембраны с эндотелием под контролем интраоперационной оптической когерентной томографии и последующая факоэмульсификация катаракты при манифестации иридокорнеального эндотелиального синдрома Чандлера после лазерной кераторефракционной операции. Клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Transplantation of Descemet’s Membrane with Endothelium and Subsequent Cataract Phacoemulsification under the Control of Intraoperative Optical Coherence Tomography in Patient with of Chandler’s Iridocorneal Endothelial Syndrome Manifestation after Laser Keratorefractive Surgery. Clinical Case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5666-3493</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малюгин</surname><given-names>Б. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyugin</surname><given-names>B. Е.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малюгин Борис Эдуардович, доктор медицинских наук, профессор, член-корреспондент РАН, заслуженный деятель науки Российской Федерации, заведующий кафедрой заболеваний роговицы глазного института Штейна и медицинской школы Дэвида Геффена</p><p>200 Stein Plaza, CA 90095-7003</p></bio><bio xml:lang="en"><p>Malyugin Boris E., MD, PhD, Professor of Ophthalmology, Joan &amp; Jerome Snyder Endowed Chair in Cornea Diseases The Stein Eye Institute and David Geffen School of Medicine at UCLA</p><p>Stein Plaza, 200, Los Angeles, CA 90095</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4775-9423</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халецкая</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaletskaya</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Халецкая Анастасия Андреевна, врач-офтальмолог</p><p>проезд Березовой рощи, 12, Москва, 125252</p></bio><bio xml:lang="en"><p>Khaletskaya Anastasia A., ophthalmologist, postgraduate of the Transplantation and optical reconstructive surgery of the anterior segment of the eyeball department</p><p>Berezovoy Roshchi travel, 12, Moscow, 125252</p></bio><email xlink:type="simple">khaletskaya261@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9918-0459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исабеков</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Isabekov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исабеков Руслан Сражудинович, врач‑офтальмолог, аспирант отдела трансплантационной и оптико‑реконструктивной хирургии переднего отрезка глазного яблока</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>Isabekov Ruslan S., postgraduate of the Transplantation and optical reconstructive surgery of the anterior segment of the eyeball department</p><p>Beskudnikovskiy blvd., 59A, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2213-2261</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>Т. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>T. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецов Тимофей Яковлевич, врач‑офтальмолог, аспирант отдела трансплантационной и оптико‑реконструктивной хирургии переднего отрезка глазного яблока</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>Kuznetsov Timophey Ya., postgraduate of the Transplantation and optical reconstructive surgery of the anterior segment of the eyeball department</p><p>Beskudnikovskiy blvd., 59A, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>UCLA Отделение офтальмологии, Институт глаза Штейна</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>The Jules Stein Eye Institute, University of California at Los Angeles</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Офтальмологическая клиника «Спектр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>OOO “Ophthalmological Clinic “Spectrum”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The S. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2025</year></pub-date><volume>22</volume><issue>1</issue><fpage>207</fpage><lpage>214</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малюгин Б.Э., Халецкая А.А., Исабеков Р.С., Кузнецов Т.Я., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Малюгин Б.Э., Халецкая А.А., Исабеков Р.С., Кузнецов Т.Я.</copyright-holder><copyright-holder xml:lang="en">Malyugin B.Е., Khaletskaya A.A., Isabekov R.S., Kuznetsov T.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2601">https://www.ophthalmojournal.com/opht/article/view/2601</self-uri><abstract><p>В статье описан клинический случай пациента, перенесшего операцию ЛАЗИК (LASIK) с целью коррекции гиперметропии на обоих глазах. В раннем послеоперационном периоде были отмечены эпизоды повышения внутриглазного давления до 27 мм рт. ст., купируемые медикаментозно. В отдаленном послеоперационном периоде появился выраженный роговичный синдром и снижение остроты зрения. После офтальмологического обследования поставлен диагноз: OU: офтальмогипертензия, гиперметропия средней степени оперированная, состояние после лазерной кераторефракционной операции, первичная эндотелиальная дистрофия роговицы Фукса, начальная катаракта, OS: скопление жидкости под роговичным лоскутом, амблиопия слабой степени. Принято решение о трансплантации эндотелия с десцеметовой мембраной на левом глазу. Операция прошла без особенностей, донорская десцеметова мембрана полностью прилегла, однако это не привело к уменьшению отека стромы роговицы и исчезновению внутрироговичной щели, заполненной жидкостью. Дополнительно пациенту была назначена гипотензивная терапия, после которой отмечена положительная динамика, а именно уменьшение отека стромы. Позднее пациенту выполнена факоэмульсификация катаракты с имплантацией ИОЛ под контролем интраоперационной оптической когерентной томографии. В статье представлен анализ данного клинического случая, обсужден выбор тактики лечения и уточнен диагноз — манифестация иридокорнеального эндотелиального синдрома Чандлера после проведенной кераторефракционной операции.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of a patient who underwent LASIK surgery to correct hyperopia in both eyes. In the early postoperative period, episodes of increased intraocular pressure up to 27 mm Hg were noted, which were relieved with medication. In the late postoperative period, severe corneal syndrome and decreased visual acuity appeared. After a thorough inspection on OU a diagnosis was put forward: Ocular hypertension. Condition after keratorefractive surgery (LASIK), primary Fuchs’ endothelial corneal dystrophy, mild hyperopia, early cataract, OS fluid accumulation under corneal flap, mild amblyopia. The decision was made to transplant the endothelium with Descemet’s membrane to the OS. The operation went as usual, the donor Descemet’s membrane was fully flattened, but it did not result in a reduction of corneal stromal edema and disappearance of the intracorneal gap filled with fluid. The patient was administered additional hypotensive therapy after which positive dynamics of stromal edema were observed. Later, the patient underwent cataract phacoemulsification under the control of intraoperative optical coherence tomography. The article presents the analysis of this clinical case, discusses the choice of treatment tactics and specifies the diagnosis as a manifestation of Chandler’s iridocorneal endothelial syndrome after keratorefractive surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иридокорнеальный эндотелиальный синдром</kwd><kwd>синдром Чандлера</kwd><kwd>LASIK</kwd><kwd>трансплантация десцеметовой мембраны</kwd><kwd>глаукома</kwd><kwd>катаракта</kwd><kwd>интраокулярная линза</kwd><kwd>интраоперационная оптическая когерентная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iridocorneal endothelial syndrome</kwd><kwd>Chandler’s syndrome</kwd><kwd>LASIK</kwd><kwd>transplantation of Descemet’s membrane</kwd><kwd>glaucoma</kwd><kwd>cataract</kwd><kwd>intraocular lens</kwd><kwd>intraoperative optical coherence tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Autrata R, Rehurek J. 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