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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-2-360-367</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2664</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Сравнительное исследование результатов визуализации угла передней камеры глаза при заболевании его первичного закрытия и при первичной открытоугольной глаукоме</article-title><trans-title-group xml:lang="en"><trans-title>The Comparative Study of the Results of Visualization of the Anterior Chamber Angle of the Eye in the Primary Angle Closure Disease and Primary Open Angle Glaucoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2265-6671</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курышева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurysheva</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курышева Наталия Ивановна доктор медицинских наук, профессор, заведующая кафедрой глазных болезней, руководитель консультативно‑диагностического отдела</p><p>46, корп. 8, Москва, 123098</p><p>ул. Гамалеи, 15, Москва, 123098</p></bio><bio xml:lang="en"><p>Kurysheva Natalia I. MD, Professor, Head of the Ophthalmology Department,  head of the Consultative and Diagnostic Department </p><p>Zhivopisnaya str., 46, bld. 8, Moscow, 123098</p><p>Gamalei str. 15, Moscow, 123098</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7163-4858</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарова</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharova</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шарова Галина Аркадьевна кандидат медицинских наук, ассистент кафедры глазных болезней,  заведующая диагностическим офтальмологическим отделением</p><p>46, корп. 8, Москва, 123098</p><p>пр. Буденного, 26, корп. 2, Москва, 105118</p></bio><bio xml:lang="en"><p>Sharova Galina A. PhD, Assistant Professor at the Ophthalmology Department,  head of the Diagnostic Ophthalmology Department </p><p>Zhivopisnaya str., 46, bld. 8, Moscow, 123098</p><p>Budenny Ave., 26/2, Moscow, 105118</p></bio><email xlink:type="simple">galina.shar@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9123-909X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубилин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubilin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трубилин Владимир Николаевич доктор медицинских наук, профессор, заведующий кафедрой офтальмологии, руководитель Центра</p><p>ул. Гамалеи, 15, Москва, 123098</p><p>Волоколамское шоссе, 91, Москва, 125371</p></bio><bio xml:lang="en"><p>Trubilin Vladimir N. MD, Professor, Head of the Ophthalmology Department </p><p>Gamalei str. 15, Moscow, 123098</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медико-биологический университет инноваций и непрерывного образования ФГБУ «Государственный научный центр Российской Федерации — «Федеральный медицинский биофизический центр им. А.И. Бурназяна» Федерального медико-биологического агентства России; Консультативно-диагностический отдел Центра офтальмологии ФГБУ «Государственный научный центр  Российской Федерации — Федеральный медицинский биофизический центр имени А.И. Бурназяна» ФМБА</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Eye Diseases at the Medical Biological University of Innovations and Continuing Education  of Federal Biophysical Center named after A.I. Burnazyan; Diagnostic Department of Ophthalmological Center of Federal Medical-Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медико-биологический университет инноваций и непрерывного образования ФГБУ «Государственный научный центр Российской Федерации — «Федеральный медицинский биофизический центр им. А.И. Бурназяна» Федерального медико-биологического агентства России; ООО «Глазная клиника доктора Беликовой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Eye Diseases at the Medical Biological University of Innovations and Continuing Education  of Federal Biophysical Center named after A.I. Burnazyan; Ophthalmology Clinic of Dr. Belikova</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Консультативно-диагностический отдел Центра офтальмологии ФГБУ «Государственный научный центр  Российской Федерации — Федеральный медицинский биофизический центр имени А.И. Бурназяна» ФМБА; Академия постдипломного образования ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Diagnostic Department of Ophthalmological Center of Federal Medical-Biological Agency; Academy of Postgraduate Education of Federal Medical and Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>27</day><month>06</month><year>2025</year></pub-date><volume>22</volume><issue>2</issue><fpage>360</fpage><lpage>367</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Курышева Н.И., Шарова Г.А., Трубилин В.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Курышева Н.И., Шарова Г.А., Трубилин В.Н.</copyright-holder><copyright-holder xml:lang="en">Kurysheva N.I., Sharova G.A., Trubilin V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2664">https://www.ophthalmojournal.com/opht/article/view/2664</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: сравнить параметры иридотрабекулярного контакта (ИТК) у пациентов с заболеванием первичного закрытия угла (ЗПЗУ) и первичной открытоугольной глаукомой (ПОУГ) на основе данных SS-OCT, а также изучить их взаимосвязь с другими клинико-анатомическими параметрами.</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. В ретроспективном исследовании проанализированы данные 89 пациентов в возрасте от 32 до 89 лет: 43 пациента с ЗПЗУ, 25 с ПОУГ и 21 из группы контроля. Всем участникам выполнена оптическая когерентная томография переднего отрезка глаза на SS-ОСТ «CASIA2» (Tomey Corporation, Nayoga, Япония), включая оценку индекса (ITC Index) и площади ИТК (ITC Area).</p></sec><sec><title>Результаты</title><p>Результаты. Параметры ИТК при ЗПЗУ были достоверно выше, чем при ПОУГ и в контроле. ITC Index = 45,40 ± 21,80 % и ITC Area = 5,81 ± 3,90 мм2 в группе ЗПЗУ против 0,01 ± 0,03 % и 0,10 ± 0,37 мм2 при ПОУГ соответственно и против 0,05 ± 0,11 % и 0,56 ± 1,17 мм2 в контроле соответственно, все р = 0,00. Значения ITC Index, а также ITC Area при ПОУГ и в контроле были сопоставимы, p = 0,21 и p = 0,25 соответственно. Выявлена взаимосвязь ITC Index и ITC Area при ЗПЗУ с глубиной передней камеры (r = –0,42, p = 0,01 и r = –0,43, p = 0,00 соответственно), высотой свода хрусталика (r = 0,35, p = 0,02 и r = 0,36, p = 0,02 соответственно), его толщиной (r = 0,47, p = 0,01 и r = 0,44, p = 0,01 соответственно) и количеством гипотензивных препаратов (r = 0,63, p = 0,01 и r = 0,68, p = 0,01 соответственно). В группах ПОУГ и контроля корреляций не выявлено.</p></sec><sec><title>Заключение</title><p>Заключение. Высокие значения параметров ИТК и их корреляции с другими клинико-анатомическими параметрами при ЗПЗУ по сравнению с таковыми при ПОУГ свидетельствуют о роли топографии переднего отрезка глаза в формировании ведущих механизмов закрытия угла передней камеры.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. To compare the iridotrabecular contact (ITC) parameters in patients with primary angle closure disease (PACD) and primary open angle glaucoma (POAG) based on SS-OCT data, and examine their relationship with other clinical and anatomical parameters.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. The retrospective study analyzed the data of 89 patients aged 32 to 89 years: 43 patients with PACD, 25 with POAG, and 21 controls. All participants underwent optical coherence tomography of the anterior segment of the eye using the SS-OСT “CASIA2” (Tomey Corporation, Nayoga, Japan), including assessment of the ITC Index and ITC Area. </p></sec><sec><title>Results</title><p>Results. ITC parameters in PACD were significantly higher than in POAG and controls. ITC Index = 45.40 ± 21.80 % and ITC Area = 5.81 ± 3.90 mm2 in the POAG group versus 0.01 ± 0.03 % and 0.1 ± 0.37 mm2 in POAG, respectively, and versus 0.05 ± 0.11 % and 0.56 ± 1.17 mm2 in the control, respectively, all p = 0.00. The values of ITC Index, as well as ITC Area in POAG and control were comparable, p = 0.21 and p = 0.25, respectively. A relationship was found between ITC Index and ITC Area in case of PACD with the depth of the anterior chamber (r = –0.42, p = 0.01 and r = –0.43, p = 0.00, respectively), the lens vault (r = 0.35, p = 0.02 and r = 0.36, p = 0.02, respectively), its thickness (r = 0.47, p = 0.01 and r = 0.44, p = 0.01, respectively) and the number of antihypertensive drugs (r = 0.63, p = 0.01 and r = 0.68, p = 0.01, respectively). No correlations were found in the POAG and control groups.</p></sec><sec><title>Conclusion</title><p>Conclusion. The high values of the parameters of the ITС and their correlation with other clinical and anatomical parameters in PACD compared with those in POAG indicate the role of the topography of the anterior segment of the eye in the formation of the leading mechanisms for the anterior angle closure.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>иридотрабекулярный контакт</kwd><kwd>заболевание первичного закрытия угла</kwd><kwd>первичная открытоугольная глаукома</kwd><kwd>оптическая когерентная томография SS-OCT</kwd><kwd>CASIA2</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iridotrabecular contact</kwd><kwd>primary angle closure disease</kwd><kwd>primary open angle glaucoma</kwd><kwd>optical coherence tomography  SS-OCT</kwd><kwd>CASIA2</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sihota R, Kumar S, Sidhu T. Is combined mechanism glaucoma a distinct entity? 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