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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-3-483-493</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2734</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Практические рекомендации при окклюзии центральной артерии сетчатки на фоне косметологического воздействия в периорбитальной зоне, механизм развития, диагностика, неотложная помощь и профилактика</article-title><trans-title-group xml:lang="en"><trans-title>Occlusion of the Central Retinal Artery by Fillers Used in Cosmetology Practice: Mechanism of Development, Diagnosis, Treatment and Prevention</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куренков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurenkov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куренков Вячеслав Владимирович - доктор медицинских наук, профессор, руководитель Клиники доктора Куренкова.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Vyacheslav V. Kurenkov - МD, Professor, chief of Ophthalmology Clinic of Dr. Kurenkov.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полунина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Polunina</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полунина Елизавета Геннадьевна - доктор медицинских наук, профессор.</p><p>Волоколамское шоссе, 91, Москва, 125371</p></bio><bio xml:lang="en"><p>Elizabet G. Poluninа - MD, Professor.</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><email xlink:type="simple">lpolunina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Ольга Александровна - кандидат медицинских наук, доцент, врач-офтальмолог.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Olga A. Vasilyeva - PhD, Associate Professor, ophthalmologist.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чиненова (Ластовская)</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chinenova (Lastovskaya)</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чиненова (Ластовская) Ксения Владимировна - кандидат медицинских наук, врач-офтальмолог.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Kseniya V. Chinenova (Lastovskaya) - PhD, ophthalmologist.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Наталья Владимировна - главный врач, врач-офтальмолог.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Nataliya V. Kuznetsova - chief physician, ophthalmologist.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самохвалова</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Samokhvalova</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самохвалова Валерия Константиновна - врач-офтальмолог.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Valeriya K. Samokhvalova – ophthalmologist.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Офтальмологическая клиника доктора Куренкова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ophthalmology Clinic of Dr. Kurenkov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Академия постдипломного образования ФГБУ «Федеральный научно-клинический центр» Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academy of Postgraduate Education of FMBA of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2025</year></pub-date><volume>22</volume><issue>3</issue><fpage>483</fpage><lpage>493</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Куренков В.В., Полунина Е.Г., Васильева О.А., Чиненова (Ластовская) К.В., Кузнецова Н.В., Самохвалова В.К., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Куренков В.В., Полунина Е.Г., Васильева О.А., Чиненова (Ластовская) К.В., Кузнецова Н.В., Самохвалова В.К.</copyright-holder><copyright-holder xml:lang="en">Kurenkov V.V., Polunina E.G., Vasilyeva O.A., Chinenova (Lastovskaya) K.V., Kuznetsova N.V., Samokhvalova V.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2734">https://www.ophthalmojournal.com/opht/article/view/2734</self-uri><abstract><p>В настоящее время эстетическая медицина получила широкое распространение в повседневной клинической практике. С увеличением числа косметологических процедур в значительной степени увеличилось число с ними связанных осложнений, которые нередко выходят за рамки эстетической медицины. Одной из распространенных форм косметологического воздействия является инъекционная терапия, которая предполагает применение различных дермальных филлеров, ботулотоксина, комплексов витаминотерапии. В данной статье описан механизм развития одного из самых тяжелых осложнений инъекционной косметологии — окклюзия центральной артерии сетчатки (ЦАС), представлен алгоритм оказания неотложной помощи пациенту при возникновении данного осложнения и методы его профилактики. Заключение. Окклюзия ЦАС — крайне редкое, но грозное осложнение, которое может возникнуть во время выполнения косметологических инъекций филлерами, практически всегда приводящее к необратимой потере зрения и слепоте. Для улучшения прогноза решающее значение имеют мгновенное распознавание признаков эмболии филлера и немедленное начало интенсивной терапии в пределах «терапевтического окна» (~60 минут). Соблюдение безопасной техники инъекций (учет анатомии, аспирационная проба, малые дозы и низкое давление на поршень шприца), использование филлеров на основе гиалуроновой кислоты в периорбитальной области и готовность врача своевременно оказать неотложную помощь позволяют минимизировать риск такого осложнения.</p></abstract><trans-abstract xml:lang="en"><p>Currently, aesthetic medicine has become widespread in everyday clinical practice. With the increase in the number of cosmetic procedures, the number of complications associated with them has increased significantly, which often go beyond the scope of aesthetic medicine. One of the common forms of cosmetology is injection therapy, which involves the use of various derma fillers, botulinum toxin, and vitamin therapy complexes. This article describes the mechanism of development of one of the most severe complications of injection cosmetology — central retinal artery occlusion, an algorithm for providing emergency care to a patient in the event of this complication and methods for its prevention. Conclusion. Central retinal artery occlusion is an extremely rare but formidable complication that can occur during cosmetic injections with fillers, almost always leading to irreversible vision loss and blindness. To improve the prognosis, immediate recognition of signs of filler embolism and immediate initiation of intensive therapy within the “therapeutic window” (~60 minutes) are crucial. Adherence to safe injection techniques (taking into account anatomy, aspiration test, small doses and low pressure on the syringe plunger), the use of hyaluronic acid-based fillers in the periorbital area and the doctor’s readiness to provide emergency care in a timely manner can minimize the risk of such a complication.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>окклюзия центральной артерии сетчатки</kwd><kwd>дермальные филлеры</kwd><kwd>косметология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>central retinal artery occlusion</kwd><kwd>dermal fillers</kwd><kwd>cosmetology</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fanfan Zhao, Yao Chen, Dong He, Xiangxi You, Yuyun Xu. Disastrous cerebral and ocular vascular complications after cosmetic facial filler injections: a retrospective case series study. 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