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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-4-725-731</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2797</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>К вопросу о возможности применения искусственного интеллекта в медицине: от теории к практике</article-title><trans-title-group xml:lang="en"><trans-title>On the Possibility of Using Artificial Intelligence in Medicine: From Theory to Practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубилин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubilin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трубилин Владимир Николаевич - доктор медицинских наук, профессор, заведующий кафедрой офтальмологии.</p><p>Волоколамское шоссе, 91, Москва, 125371</p></bio><bio xml:lang="en"><p>Trubilin Vladimir N. - МD, Professor, head of the Ophthalmology Department.</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8551-0661</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полунина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Polunina</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полунина Елизавета Геннадьевна - доктор медицинских наук, профессор, профессор кафедры офтальмологии.</p><p>Волоколамское шоссе, 91, Москва, 125371</p></bio><bio xml:lang="en"><p>Poluninа Elizabet G. - MD, Professor, Professor of the Ophthalmology Department.</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><email xlink:type="simple">lpolunina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куренков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurenkov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куренков Вячеслав Владимирови - доктор медицинских наук, профессор, руководитель Клиники доктора Куренкова.</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Kurenkov Vyacheslav V. - МD, Professor, chief of Ophthalmology Clinic of Dr. Kurenkov.</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-5112-5321</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубилин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubilin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трубилин Александр Владимирович = кандидат медицинских наук, доцент кафедры офтальмологии.</p><p>Волоколамское шоссе, 91, Москва, 125371</p></bio><bio xml:lang="en"><p>Trubilin Alexander. V. - PhD, Associate Professor of the Ophthalmology Department.</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6732-1226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кечин</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kechin</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кечин Евгений Владимирович - кандидат медицинских наук, начальник отдела реализации инновационных программ, трансфера и коммерциализации технологий.</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>Kechin Evgeny V. - PhD, head of the Department for Implementation of Innovation Programs, Transfer and Commercialization of Technologies.</p><p>Beskudnikovskiy Blvd, 59a, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каспарова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasparova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каспарова Евгения Аркадьевна - кандидат медицинских наук, ведущий научный сотрудник.</p><p>Ул. Россолимо, 11а, б, Москва, 119021</p></bio><bio xml:lang="en"><p>Kasparova Evgeniya A. - PhD, senior research officer.</p><p>Rossolimo str., 11A, B, Moscow, 119021</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арабаджян</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Arabadzhyan</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Арабаджян Сергей Игоревич - кандидат медицинских наук, доцент кафедры репродуктивной медицины клинической эмбриологии и генетики.</p><p>Ул. Чапаевская, 89, Самара, 443099</p></bio><bio xml:lang="en"><p>Arabadzhjan Sergey I. - PhD, Associate Professor of the Department of Reproductive Medicine, Clinical Embryology and Genetics.</p><p>Chapaevskaya str., 89, Samara, 443099</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филоненко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Filonenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филоненко Александра Вячеславовна - врач-офтальмолог, заведующая офтальмологическим отделением.</p><p>Ул. Павла Мочалова, 8, Нижний Новгород 603003</p></bio><bio xml:lang="en"><p>Filonenko Alexandra V. - ophthalmic surgeon, head of the Ophthalmology Department.</p><p>Pavel Mochalov str., 8, Nizhny Novgorod, 603003</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomareva</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пономарева Елена Николаевна - врач-офтальмолог, заведующая офтальмологическим отделением.</p><p>Ореховый бульвар, 28, Москва, 115682</p></bio><bio xml:lang="en"><p>Ponomareva Elena N. ophthalmic surgeon, head of the Ophthalmology Department.</p><p>Orekhovy Blvd., bldg. 28, Moscow, 115682</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царегородцева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsaregorodtseva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Царегородцева Мария Александровна - врач-офтальмолог.</p><p>Ореховый бульвар, 28, Москва, 115682</p></bio><bio xml:lang="en"><p>Tsaregorodtseva Marina A. - ophthalmic surgeon.</p><p>Orekhovy Blvd., bldg. 28, Moscow, 115682</p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Академия постдипломного образования ФГБУ «Федеральный научно-клинический центр» Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academy of postgraduate education of FMBA of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Офтальмологическая клиника доктора Куренкова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ophthalmology Clinic of Dr. Kurenkov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. академика С.Н. Федорова» Министерства здравоохранения</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт глазных болезней имени М.М. Краснова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnov Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ГБУЗ НО «Городская клиническая больница № 12» Сормовского района г. Нижнего Новгорода</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 12 of Sormovsky District of Nizhny Novgorod</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Федеральный научно-клинический центр Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Scientific and Clinical Center of the Federal Medical and Biological Agency of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2025</year></pub-date><volume>22</volume><issue>4</issue><fpage>725</fpage><lpage>731</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трубилин В.Н., Полунина Е.Г., Куренков В.В., Трубилин А.В., Кечин Е.В., Каспарова Е.А., Арабаджян С.И., Филоненко А.В., Пономарева Е.Н., Царегородцева М.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Трубилин В.Н., Полунина Е.Г., Куренков В.В., Трубилин А.В., Кечин Е.В., Каспарова Е.А., Арабаджян С.И., Филоненко А.В., Пономарева Е.Н., Царегородцева М.А.</copyright-holder><copyright-holder xml:lang="en">Trubilin V.N., Polunina E.G., Kurenkov V.V., Trubilin A.V., Kechin E.V., Kasparova E.A., Arabadzhyan S.I., Filonenko A.V., Ponomareva E.N., Tsaregorodtseva M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2797">https://www.ophthalmojournal.com/opht/article/view/2797</self-uri><abstract><p>Жизнь современного человека неразрывно связана с новейшими технологиями. Новый вызов человечеству бросает искусственный интеллект (ИИ), применение которого затрагивает все сферы жизни, включая медицину. В данной статье рассмотрены возможности применения ИИ в медицинской практике, в частности в офтальмологии, представлен пример возможности использования ИИ при определении факторов риска развития синдрома сухого глаза у пациентов с косметологическим воздействием в периорбитальной зоне, а также проанализированы ограничения, с которыми можно столкнуться при использовании ИИ в медицине. Анализ данных литературы показал, что применение в научной и медицинской практике ИИ открыло широкий спектр возможностей для проведения исследований на новом технологическом уровне, таких как скрининговые профилактические обследования, диагностика, основанная на анализе изображений, прогнозирование возникновения и развития заболеваний; подбор оптимальных дозировок лекарственных препаратов; сокращение угроз пандемий, автоматизация и точность хирургических вмешательств. В ходе интеграции технологий ИИ в медицинскую практику необходимо учитывать целый спектр этических проблем, таких как возможное нарушение конфиденциальности, прозрачности и достоверности полученной информации. Частое применение чат-ботов может стать причиной совершения ошибок и деквалификации врачей, особенно с низким уровнем клинического опыта, а также способно привести к нарушению коммуникации между врачом и пациентом. Кроме того, важно учитывать юридические и судебно-медицинские аспекты, в первую очередь касающиеся вопроса ответственности в принятии решений. Учитывая вышесказанное, в повседневной клинической практике, на наш взгляд, в приоритете остается персонализированный подход в лечении каждого конкретного пациента с учетом не только объективных показателей, но и анамнестических данных, индивидуальных реакций организма на проводимое лечение, психоэмоциональных аспектов на базе фундаментальных знаний и опыта врача.</p></abstract><trans-abstract xml:lang="en"><p>Modern life is inextricably linked with the latest technologies. Artificial intelligence (AI) poses a new challenge to humanity, the application of which affects all areas of life, including medicine. This article examines the potential application of AI in medical practice, particularly in ophthalmology. It presents an example of how AI can be used to determine risk factors for dry eye syndrome in patients undergoing cosmetic procedures in the periorbital area. It also analyzes the limitations of AI in medicine. An analysis of the literature demonstrates that the use of AI in scientific and medical practice has opened up a wide range of opportunities for conducting research at a new technological level, such as screening examinations, image-based diagnostics, and disease prediction; selection of optimal drug dosages; mitigating the threat of pandemics; and automation and precision of surgical interventions. When integrating AI technologies into medical practice, it’s important to consider a wide range of ethical issues, including potential breaches of confidentiality, transparency, and the reliability of information received. Frequent use of chatbots can lead to errors and the dequalification of physicians, especially those with limited clinical experience, as well as disruption of doctor-patient communication. Furthermore, it’s important to consider legal and forensic issues, primarily the question of who will bear responsibility for making decisions. Given the above, in our view, a personalized approach to treating each individual patient remains a priority in everyday clinical practice. This approach takes into account not only objective indicators but also anamnestic data, the body’s individual responses to treatment, and psycho-emotional aspects, as well as the physician’s fundamental knowledge and experience.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>офтальмология</kwd><kwd>искусственный интеллект</kwd><kwd>глазная поверхность</kwd><kwd>сухой глаз</kwd><kwd>факторы риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ophthalmology</kwd><kwd>artificial intelligence</kwd><kwd>ocular surface</kwd><kwd>dry eye</kwd><kwd>risk factors</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">никто из авторов не имеет финансовой заинтересованности в представленных материалах или методах</funding-statement><funding-statement xml:lang="en">Financial Disclosure: no author has a financial or property interest in any material or method mentioned</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Хохлов АЛ, Зарубина ТВ, Котловский МЮ, Павлов АВ, Потапов МП, Солдатова ОН. 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