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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2025-4-847-852</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2813</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Оптическая когерентная томография-ангиография в диагностике микроциркуляции глазного дна у пациентов в постковидном периоде</article-title><trans-title-group xml:lang="en"><trans-title>Optical Coherence Tomography-angiography in the Diagnostics of Fundus Microcirculation in Patients in the Post-COVID Period</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дорофеева</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dorofeeva</surname><given-names>Ya. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дорофеева Яна Викторовна - врач-офтальмолог.</p><p>Мичуринский проспект, 6, Москва,119285</p></bio><bio xml:lang="en"><p>Dorofeeva Yana V. – ophthalmologist.</p><p>Michurinsky ave., 6, Moscow, 119285</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мякошина</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Myakoshina</surname><given-names>E. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мякошина Елена Борисовна - доктор медицинских наук, врач-офтальмолог.</p><p>Мичуринский проспект, 6, Москва,119285</p></bio><bio xml:lang="en"><p>Myakoshina Elena B. - MD, ophthalmologist.</p><p>Michurinsky ave., 6, Moscow, 119285</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Объединенная больница с поликлиникой» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>United Hospital with a Polyclinic of the Presidential Executive Office of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2025</year></pub-date><volume>22</volume><issue>4</issue><fpage>847</fpage><lpage>852</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дорофеева Я.В., Мякошина Е.Б., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Дорофеева Я.В., Мякошина Е.Б.</copyright-holder><copyright-holder xml:lang="en">Dorofeeva Y.V., Myakoshina E.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2813">https://www.ophthalmojournal.com/opht/article/view/2813</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить плотность сосудов сетчатки парафовеолярной и перипапиллярной зон и области ДЗН у пациентов в постковидном периоде с помощью ОКТ-А.</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. Обследованы 30 человек (60 глаз) в возрасте от 18 до 82 (в среднем 61,7 ± 14,2) лет. Все исследуемые имели в анамнезе новую коронавирусную инфекцию COVID-19 различной степени тяжести, подтвержденную положительным результатом на РНК SARS-CoV-2 методом ПЦР. ОКТ-А выполняли на приборе Optopol SOCT Copernicus REVO NX, (Польша).</p></sec><sec><title>Результаты</title><p>Результаты. Плотность сосудов поверхностного и глубокого капиллярного сплетения сетчатки парафовеолярной зоны во всех квадрантах (носовом, нижнем, височном и верхнем) оказалась значимо ниже по сравнению с нормальными показателями соответствующих зон (р &lt; 0,001). Доказано значимое снижение показателей микроциркуляции всех исследуемых параметров ДЗН по сравнению с нормальными значениями (р &lt; 0,001). При этом наименьшей оказалась плотность сосудистого русла внутри ДЗН, составляя 29,6 ± 5,6 % для правого глаза и 27,9 ± 6,4 % для левого, что оказалось значимо ниже нормальных показателей 52,9 ± 3,6 %, р &lt; 0,001.</p></sec><sec><title>Заключение</title><p>Заключение. Проведенные с помощью ОКТ-А исследования доказали микроциркуляторные изменения глазного дна у пациентов, перенесших новую коронавирусную инфекцию. Так, выявлено значимое снижение плотности сосудов как в парафовеолярной, так и в перипапиллярной зонах сетчатки, а также в области ДЗН, что может свидетельствовать о развитии доклинической макулопатии и оптической нейропатии. Полученные данные дают возможность продолжить начатые исследования с целью разработки и применения реабилитационных мероприятий на начальных этапах развития заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: tо study the retinal vessel density of the parafoveal and peripapillary zones and the optic disc area in patients in the postCOVID period using OCT-A.</p></sec><sec><title>Patients and methods</title><p>Patients and methods: A total of 30 people (60 eyes) aged 18 to 82 (average 61.7 ± 14.2) years were examined at the Federal State Budgetary Institution “United Hospital and Polyclinic” of the Presidential Executive Office of the Russian Federation. All subjects had a history of a new coronavirus infection COVID-19 of varying severity, confirmed by a positive result for SARS-CoV-2 RNA by PCR. OCT-A was performed on an Optopol SOCT Copernicus REVO NX device (Poland).</p></sec><sec><title>Results</title><p>Results. The vessel density of the superficial and deep retinal capillary plexus of the parafoveal zone in all quadrants (nasal, inferior, temporal and superior) was significantly lower compared to the normal values of the corresponding zones (p &lt; 0.001). A significant decrease in the microcirculation parameters of all studied optic disc parameters was proven compared to normal values (p &lt; 0.001). At the same time, the vascular bed density inside the optic disc was the lowest, amounting to 29.6 ± 5.6 % for the right eye and 27.9 ± 6.4 % for the left, which was significantly lower than the normal values of 52.9 ± 3.6 %, p &lt; 0.001.</p></sec><sec><title>Conclusion</title><p>Conclusion. The studies conducted using OCT-A proved microcirculatory fundus’ changes in patients after a new coronavirus infection. Thus, a significant decrease in the vascular density was revealed both in the retina’s parafoveal and peripapillary zones, as well as in the optic nerve head area, which may indicate the development of preclinical maculopathy and optic neuropathy. The obtained data made it possible to continue the studies initiated in order to develop and apply rehabilitation measures at the initial stages of the disease.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>постковидный период</kwd><kwd>оптическая когерентная томография-ангиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>post-COVID period</kwd><kwd>optical coherence tomography angiography</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">никто из авторов не имеет финансовой заинтересованности в представленных материалах или методах</funding-statement><funding-statement xml:lang="en">no author has a financial or property interest in any material or method mentioned</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Нероев ВВ, Киселева ТН, Елисеева ЕК. 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