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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2026-1-195-198</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-2892</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ЕXPERIMENTAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Оптимизация метода транссклеральной лазерной циклотермотерапии (экспериментальное исследование)</article-title><trans-title-group xml:lang="en"><trans-title>Optimization of Transscleral Laser Cyclothermotherapy Method (experimental study)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1345-9537</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцов</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvortsov</surname><given-names>V. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Скворцов Вячеслав Юрьевич – кандидат медицинских наук, преподаватель кафедры офтальмологии </p><p>ул. Академика Лебедева, 6ж, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Skvortsov Vyacheslav Yu., PhD, lecturer, Department of Ophthalmology </p><p>Akademician Lebedev str., 6zh, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5274-6993</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликов Алексей Николаевич – доктор медицинских наук, профессор, начальник кафедры и клиники офтальмологии</p><p>ул. Академика Лебедева, 6ж, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Kulikov Alexey N., MD, Professor, head of the Department and Clinic of Ophthalmology </p><p>Akademician Lebedev str., 6zh, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3485-8227</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулин</surname><given-names>Д. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Tulin</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тулин Дмитрий Валерьевич – врач‑офтальмолог клиники офтальмологии </p><p>ул. Академика Лебедева, 6ж, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Tulin Dmitry V., ophthalmologist, Clinic of Ophthalmology</p><p>Akademician Lebedev str., 6zh, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» Министерства обороны Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2026</year></pub-date><volume>23</volume><issue>1</issue><fpage>195</fpage><lpage>198</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Скворцов В.Ю., Куликов А.Н., Тулин Д.B., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Скворцов В.Ю., Куликов А.Н., Тулин Д.B.</copyright-holder><copyright-holder xml:lang="en">Skvortsov V.Y., Kulikov A.N., Tulin D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/2892">https://www.ophthalmojournal.com/opht/article/view/2892</self-uri><abstract><sec><title>Цель</title><p>Цель: определить возможность сокращения времени экспозиции при транссклеральной лазерной циклотермотерапии (ТЛЦТТ) за счет применения импульсно-периодического режима работы лазера в экспериментальных условиях. </p></sec><sec><title>Методы</title><p>Методы. Исследование выполнено на кроликах породы шиншилла обоего пола массой 1,5–2,0 кг. Животные были разделены на две группы. В контрольной группе (20 кроликов, 40 глаз) ТЛЦТТ выполняли в непрерывном режиме (0,3 Вт, 16 с). В экспериментальной группе (10 кроликов, 20 глаз) использовали импульсно-периодический режим (коэффициент заполнения 50 %, длительность импульса 1 с) при мощности 0,6 Вт и экспозиции 8 с. Для оценки воспалительной реакции проводили биомикроскопию на первые сутки после вмешательства, а макроскопическое исследование препаратов ресничного тела выполняли для характеристики очагов деструкции. </p></sec><sec><title>Результаты</title><p>Результаты. Биомикроскопия выявила смешанную инъекцию конъюнктивы у всех животных, умеренный хемоз отмечен у 45 % глаз контрольной и у 50 % глаз экспериментальной группы. Опалесценция влаги передней камеры средней выраженности зарегистрирована у 75 и 80 % глаз соответственно. Преципитатов, задних синехий и фибринозных наложений не обнаружено. Макроскопически очаги деструкции имели вид бледных участков ресничных отростков с сопоставимыми диаметрами (1,35 ± 0,07 мм в контрольной и 1,34 ± 0,08 мм в экспериментальной группе, p = 0,3). Механических эффектов, связанных с разрывом тканей, не выявлено в обеих группах. </p></sec><sec><title>Заключение</title><p>Заключение. Импульсно-периодический режим лазера формировал очаги деструкции, сопоставимые по размерам с традиционной ТЛЦТТ без дополнительного механического повреждения и избыточного воспаления. Сокращение времени экспозиции снижает риск смещения световода в ходе вмешательства и может способствовать повышению безопасности и эффективности метода.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objectives</title><p>Objectives: to evaluate the feasibility of reducing exposure time during transscleral laser cyclothermotherapy (TLCTT) by applying a pulsedperiodic laser mode in an experimental setting. </p></sec><sec><title>Methods</title><p>Methods. The study was conducted on Chinchilla rabbits of both sexes, weighing 1.5–2.0 kg. Animals were divided into two groups. The control group (20 rabbits, 40 eyes) underwent TLCTT using a continuous laser mode (0.3 W, 16 s). The experimental group (10 rabbits, 20 eyes) received TLCTT with a pulsed-periodic laser mode (duty cycle 50 %, pulse period 1 s), at 0.6 W for 8 s. Biomicroscopy was performed one day after the procedure to evaluate inflammatory response, and macroscopic examination of ciliary body specimens was carried out to assess the characteristics of destruction foci. </p></sec><sec><title>Results</title><p>Results. Biomicroscopy revealed mixed conjunctival injection in all animals, with moderate chemosis in 45 % of eyes in the control group and 50 % in the experimental group. Aqueous humor opalescence of moderate intensity was noted in 75 % and 80 % of eyes, respectively. No precipitates, posterior synechiae, or fibrinous deposits were observed. Macroscopically, destruction foci appeared as pale areas of ciliary processes with comparable diameters (1.35 ± 0.07 mm in the control group and 1.34 ± 0.08 mm in the experimental group, p = 0.3). No rupture-associated mechanical effects were detected in either group. </p></sec><sec><title>Conclusion</title><p>Conclusion. The pulsed-periodic laser mode achieved destruction foci of comparable size to conventional TLCTT, without inducing additional mechanical damage or excessive postoperative inflammation. The shortened exposure time reduces the risk of light guide displacement during the procedure, potentially improving both safety and effectiveness.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>глаукома</kwd><kwd>транссклеральная лазерная циклотермотерапия</kwd><kwd>циклодеструкция</kwd><kwd>ресничное тело</kwd><kwd>внутриглазное давление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glaucoma</kwd><kwd>transscleral laser cyclothermotherapy</kwd><kwd>cyclodestruction</kwd><kwd>ciliary body</kwd><kwd>intraocular pressure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M; Early Manifest Glaucoma Trial Group. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. 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