ophthalmologyОфтальмологияOphthalmology in Russia1816-50952500-0845Ophthalmology10.18008/1816-5095-2014-1-4-11ophthalmology-29Research ArticleОБЗОРЫREVIEWSНелинейные фракталы: приложения в физиологии и офтальмологии. ОбзорNonlinear fractals: applications in physiology and ophthalmologyЗуеваМ. В.ZuevaM. V.visionlab@yandex.ruФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава РоссииРоссияMoscow Helmholtz Research Institute of Eye Diseases of Ministry of health of Russian FederationRussian Federation201409072014111411Copyright © Зуева М.В., 20142014Зуева М.В.Zueva M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ophthalmojournal.com/opht/article/view/29

Фрактальная геометрия и нелинейная динамика имеют приложения в области биологии и медицины. Многие сложные структуры живых систем проявляют фракталоподобную геометрию, и особое внимание привлекают вопросы нелинейности анатомических структур человека и его физиологических функций. Представлен обзор мультидисциплинарных исследований, демонстрирующих мультимасштабную нелинейную сложность физиологических функций и фрактальную геометрию анатомических структур здорового человека, включая сетчатку, которые упрощаются или усложняются при заболеваниях и в процессе старения человека. Патологические состояния часто вызывают развитие высоко периодичной динамики процессов, доминирующей на одном масштабе времени. В развитие приложений нелинейной динамики в физиологии зрительной системы и офтальмологии предложены исследования влияния фрактального мелькающего светового фона на электрогенез сетчатки и зрительной коры. Предполагается, что эти знания могут лечь в основу новых методов электрофизиологической диагностики и лечения заболеваний зрительной системы.

Fractal geometry and nonlinear dynamics have applications in the field of biology and medicine. Many complex structures of living systems reveal fractal-like geometry. Among them, nonlinearity of human anatomic structures and physiologic functions are of special interest. Here, we review several multidisciplinary studies that demonstrate multi-scale nonlinear complexity of physiological functions and fractal geometry of anatomical structures of a healthy human including retina. With ageing and diseases, these entities become simpler or more complex. Pathologic conditions contribute to highly periodic dynamics of processes that dominates on a time scale. Nonlinear dynamics application in ophthalmology and physiology of visual system can be promoted by the studies of fractal flickeringbackground and its impact on retina and visual cortex electrical activity. The next step will be the development of novel electrophysiological diagnostics and visual system impairment treatment

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The authors declare that there are no conflicts of interest present.