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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2016-4-235-240</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-332</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL &amp; EXPERIMENTAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Методы скрининговой диагностики дисфункции мейбомиевых желез</article-title><trans-title-group xml:lang="en"><trans-title>Methods of Screening for Meibomian Gland Dysfunction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубилин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubilin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой офтальмологии</p></bio><bio xml:lang="en"><p>МD., рrofessor, Head of the Department of Ophthalmology</p></bio><email xlink:type="simple">trubilinmd@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полунина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Polunina</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., доцент кафедры офтальмологии</p></bio><bio xml:lang="en"><p>MD, assistant professor of the Department of Ophthalmology</p></bio><email xlink:type="simple">lpolunina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Markova</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., заведующая отделом микрохирургии и реабилитации глаза у детей, профессор кафедры офтальмологии</p></bio><bio xml:lang="en"><p>MD, head of the of microsurgery and rehabilitation of the eye in children</p></bio><email xlink:type="simple">markova_ej@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анджелова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Andzhelova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., старший научный сотрудник отдела многофункциональной дианостики</p></bio><bio xml:lang="en"><p>MD, Senior Researcher</p></bio><email xlink:type="simple">andgelova@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куренкова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurenkova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ординатор</p></bio><bio xml:lang="en"><p>postgraduate</p></bio><email xlink:type="simple">serafimakurenkova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безмельницына</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezmel’nitsyna</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ведущий научный сотрудник сектора координации научных исследований и информации</p></bio><bio xml:lang="en"><p>Leading Researcher</p></bio><email xlink:type="simple">blyu18@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Институт повышения квалификации Федерального медико-биологического агентства»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal institute of the professional development, Federal medical and biological agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Институт повышения квалификации Федерального медико-биологического агентства», Клинический Госпиталь Лапино «Мать и дитя»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal institute of the professional development, Federal medical and biological agency, Clinical Hospital Lapino “Mother and Child”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Межотраслевой научно-технический комплекс «Микрохирургия глаза» имени академика С.Н. Федорова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The S. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение Научно-исследовательский институт глазных болезней</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Eye Diseases,Scientific institution “The National Research Institute of Public Health named Semashko“</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Национальный научно-исследовательский институт общественного здоровья им. Н.А. Семашко»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific institution “The National Research Institute of Public Health named Semashko“</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>21</day><month>12</month><year>2016</year></pub-date><volume>13</volume><issue>4</issue><fpage>235</fpage><lpage>240</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трубилин В.Н., Полунина Е.Г., Маркова Е.Ю., Анджелова Д.В., Куренкова С.В., Безмельницына Л.Ю., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Трубилин В.Н., Полунина Е.Г., Маркова Е.Ю., Анджелова Д.В., Куренкова С.В., Безмельницына Л.Ю.</copyright-holder><copyright-holder xml:lang="en">Trubilin V.N., Polunina E.G., Markova E.Y., Andzhelova D.V., Kurenkova S.V., Bezmel’nitsyna L.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/332">https://www.ophthalmojournal.com/opht/article/view/332</self-uri><abstract><p>РЕЗЮМЕ    Актуальность своевременной диагностики дисфункции мейбомиевых желез (ДМЖ) возрастает с каждым днем. В первую очередь, это связано с тем, что в настоящее время изменились представления о распространенности данной патологии, которая по разным данным составляет от 40 до 71% населения в различных возрастных группах. Учитывая возрастающее число пациентов, страдающих ДМЖ, возникает необходимость разработки скрининговых методов диагностики данной патологии. Скрининговые методы должны быть доступны не только для узких специалистов, занимающихся лечением кератоконъюнктивального ксероза в специализированных офтальмологических клиниках, но и в условиях поликлинического приема. Важным аспектом в диагностике степени тяжести нарушения функционального состояния мейбомиевых желез является оценка ихморфологического состояния, что определяет дальнейший выбор терапии. Для оценки морфофункционального состояния мейбомиевых желез предложено применять биометрию мейбомиевых желез. Исследование выполняют с помощью щелевой лампы. Кроме того, объективные данные, характеризующие морфофункциональное состояние мейбомиевых желез, можно получить при проведении мейбографии. Для визуализации мейбомиевых желез при мейбографии авторы применяли не только белый свет, но и инфракрасное освещение. В качестве осветительных приборов возможно использование многофункциональных офтальмологических приборов, оснащенных инфракрасным освещением. К ним относятся специализированные щелевые лампы, кератотопографы, Шеймпфлюг камера, фундус-камера и др. В своей практике для визуализации мейбомиевых желез мы применяли немидриатическую фундус-камеру TOPCON TRC-NW300, предназначенную для фоторегистрации глазного дна. Особенностью предложенной методики — мейбоскопии — является простота в применении и отсутствие необходимости в получении определенных навыков исследователю при сканировании внутренней поверхности века фундус-камерой. Мейбоскопия нетребует дополнительного оборудования и программного обеспечения фундус-камеры, при этом позволяет получать объективное качественное видеоизображение мейбомиевых желез, что открывает новые диагностические возможности. Расширение их диапазона при выявлении ДМЖ на основе скрининговых методов обследования позволит своевременно оценивать степень тяжести данной патологии и назначать патогенетически обоснованную терапию.</p></abstract><trans-abstract xml:lang="en"><p>The relevance of the modern diagnosis of meibomian glands dysfunction (MGD) increases daily. Firstly, it is caused by changing of the perception about the prevalence of this disease, according to various data it is from 40 to 71% of the population in different age groups. Considering the increasing number of patients suffering from MGD, there is the need to develop screening methods for diagnosis of this disease. Screening methods should be available not only for specialists involved in the treatment of xerosis keratoconjunctival in specialized ophthalmology clinics, but also in out-patient sector. An important aspect in the diagnosis of the severity of the functionaldisorders of the meibomian glands is the assessment of morphological status that determines the further choice of therapy. To evaluate the morphological and functional state of the meibomian glands proposed to use biometrics of meibomian glands. A slit lamp is used for examination. Furthermore, objective data characterizing the morpho-functional state of the meibomian glands, can be obtained by carrying out meibography. Authors used not only white light but also infrared light for the visualization of meibomian glands during meibography. The multifunctional ophthalmic devices equipped with infrared lighting can be used for lighting. For example, specialized slit lamps, corneal topographs, Sheympflyug camera, the fundus camera and others. We applied nonmidriatic fundus camera TOPCON TRC-NW300, using for fotoregistration of the ocular fundus. A feature of the proposed method — meyboskopy — was simplicity and absence of necessity of the investigator skills by scanning with the fundus camera of the inner surface of the eyelid. Meiboskopy doesn’t require  additional equipment and software of the fundus camera and allows to receive objective quality video of meibomian glands, it opens new diagnostic possibilities. Extending of the range of diagnostic capabilities in detecting of MGD based on the screening methods will allow time to assess the severity of this disease and to appoint pathogenetically substantiated therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мейбомиевы железы</kwd><kwd>дисфункция</kwd><kwd>скрининг</kwd><kwd>мейбография</kwd><kwd>мейбоскопия</kwd><kwd>фундус-камера</kwd></kwd-group><kwd-group xml:lang="en"><kwd>meibomian glands dysfunction</kwd><kwd>screening</kwd><kwd>meibography</kwd><kwd>meiboskopy</kwd><kwd>fundus camera</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fogt JS, Kowalski MJ, King-Smith PE, Epitropolous AT, Hendershot AJ, Lembach C, Maszczak JP, Jones-Jordan LA, Barr JT.Tear lipid layer thickness with eye drops in meibomian gland dysfunction. 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