<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2017-2-163-169</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-379</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>МИНИИНВАЗИВНЫЕ МЕТОДЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ЭНДОКРИННОЙ ОФТАЛЬМОПАТИИ</article-title><trans-title-group xml:lang="en"><trans-title>MINIMALLY INVASIVE METHODS OF SURGICAL TREATMENT OF ENDOCRINE OPHTHALMOPATHY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левченко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Levchenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левченко Олег Валерьевич — доктор медицинских наук, проректор  по лечебной работе.</p><p>Делегатская ул., 20/1, Москва, 127473</p></bio><bio xml:lang="en"><p>Levchenko Oleg V. — PhD, Vice‑rector for clinical work.</p><p>Delegate  Str. 20/1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каландари</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalandari</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каландари Алик Амиранович  — кандидат медицинских наук, заведующий операционным отделением.</p></bio><bio xml:lang="en"><p>Kalandari Alic A. — MD, head of the operational  Department.</p><p>Delegate  Str. 20/1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoriev</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьев Андрей Юрьевич — доктор медицинских наук, заведующий нейрохирургическим отделением.</p><p>Ул. Дмитрия Ульянова,  11, Москва, 117292</p></bio><bio xml:lang="en"><p>Grigoriev Andrey Yu. — PhD, neurosurgeon, head of neurosurgical Department.</p><p>Dmitry Ulyanov str., 11, Moscow, 117292</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутровская</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutrovskaya</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутровская Наталья Юрьевна — кандидат медицинских наук, нейроофтальмолог.</p></bio><bio xml:lang="en"><p>Kutrovskaya Nataly Yu. — MD, neuroophthalmologist.</p><p>Delegate  Str. 20/1, Moscow, 127473</p></bio><email xlink:type="simple">kutrovskaya.natalia@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Timofeeva</surname><given-names>О. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимофеева Оксана Николаевна — кандидат медицинских наук, заведующий отделением офтальмологии.</p><p>Ул. Пречистенка, 37, Москва, 119034</p></bio><bio xml:lang="en"><p>Timofeeva Оlga. N.— MD, head of the Department of ophthalmology.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Московский государственный медико-стоматологический университет  им. А.И. Евдокимова  МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State Universit y of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Эндокринологический  научный центр» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ «Эндокринологический  диспансер ДЗ г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology health  center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>07</month><year>2017</year></pub-date><volume>14</volume><issue>2</issue><fpage>163</fpage><lpage>169</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Левченко О.В., Каландари А.А., Григорьев А.Ю., Кутровская Н.Ю., Тимофеева О.Н., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Левченко О.В., Каландари А.А., Григорьев А.Ю., Кутровская Н.Ю., Тимофеева О.Н.</copyright-holder><copyright-holder xml:lang="en">Levchenko O.V., Kalandari A.A., Grigoriev A.Y., Kutrovskaya N.Y., Timofeeva О.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/379">https://www.ophthalmojournal.com/opht/article/view/379</self-uri><abstract><p>«Сбалансированная» костная  декомпрессия орбиты была выполнена  пациентке с эндокринной  офтальмопатией, CAS3, ОD=30 мм,  ОS=31  мм  с  использованием миниинвазивных  трансконъюнктивальных доступов  и безрамной  нейронавигации. Первым этапом  данные предоперационной компьютерной  томографии орбит импортировали в программное обеспечение навигационной установки,  отмечали  область  предполагаемой резекции стенок  глазницы.  Далее  в условиях операционной  выполняли регистрацию пациента  в системе навигации.  Для  выполнения  костной  декомпрессии глазницы  и липэктомии  мы применяли  пресептальный,  транскарункулярный и разработанный латеральный ретрокантальный доступы. Данные  доступы являются трансконъюнктивальными  и не оставляют послеоперационных рубцов.  По завершении выполнения  костной  декомпрессии глазницы  ее точность и размеры определяли интраоперционным поинтером нейронавигационной системы.</p><sec><title>Результаты</title><p>Результаты. Послеоперационный период протекал без особенностей. В раннем послеоперационном периоде  отмечено  регрессирование экзофтальма ОD=26 мм, ОS=27 мм, смыкание  глазной  щели,  однако  сохранялась ретракция век.  При осмотре  через  3 месяца после  операции  регресс экзофтальма составил ОD=23  мм,  ОS=24  мм,  ретракция век  — 1 мм,  при отведении  — доведение до латеральной спайки. При осмотре  через  6 месяцев — положение глазных  яблок  в орбите:  ОD=21  мм,  ОS=22  мм,  ретракции  век  нет, нарушения окуломоторики  нет, осложнений не  зафиксировано. Получен удовлетворительный результат.</p></sec><sec><title>Заключение</title><p>Заключение. Миниинвазивные трансорбитальные доступы позволяют  осуществить подход ко всем  стенкам глазницы  трансконъюнктивально, выполнить  декомпрессию  орбиты  и липэктомию  без  кожных разрезов, достигнуть  хороших косметических и функциональных  результатов. А интраоперационное использование нейронавигационной системы  обеспечивает выполнение  костной декомпрессии орбиты в полном объеме. Методика  является перспективной и требует дальнейших  рандомизированных исследований.</p></sec></abstract><trans-abstract xml:lang="en"><p>“Balanced” bone  decompression of the  orbit was  performed in a patient  with endocrine ophthalmopathy, CAS3, OD=30 mm,  OS=31 mm with the use of minimally invasive transconjunctival approaches and frameless neuronavigation. At the first stage the preoperative computed  tomography  of  the  orbits   was  imported   into  the  navigation  software,  and  then   marked  the  area of  the  proposed resection of the  orbit  walls. Further, in the  operating room,  the  patient  was  registered in the  navigation system. To perform  bone decompression of the orbit and lipectomy, we used  preseptal, transcaruncular and lateral retrocanthal approaches. These approaches are  transconjunctival and  do not  leave postoperative scars. Upon completion  of the  orbitotomy, its accuracy and  dimensions were determined by the intraoperative pointer of the neuronavigation system.</p><sec><title>Results</title><p>Results. The postoperative period was uneventful. In the early postoperative period there was a regression of exophthalmus OD=26 mm,  OS=27  mm,  closure  of the  eye gap,  but retraction of the eyelids remained. When examined 3 months after the operation, the exophthalmic regression was OD=23 mm, OS=24 mm, retraction of the  eyelids — 1 mm,  with lead — finishing to the  lateral  adhesion. When  examined  after  6 months — the  position of the  eyeballs in orbit: ОD=21 mm,  ОS=22  mm,  retraction of the  eyelids is not present, there is no violation of oculomotorics, complications were not recorded. A satisfactory result  was  obtained.</p></sec><sec><title>Conclusion</title><p>Conclusion. Minimally invasive transorbital approaches allow the  transconjunctival acces to all orbital walls to perform  decompression of the  orbit and lipectomy without cutaneous incisions,  to achieve good cosmetic and functional results. And the intraoperative use  of the neuronavigation system ensures  the bone decompression of the orbit in full. The technique is promising  and requires further  randomized  studies.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>эндокринная офтальмопатия</kwd><kwd>«сбалансированная» декомпрессия глазницы</kwd><kwd>нейронавигация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endocrine ophthalmopathy</kwd><kwd>“balanced” decompression of the orbit</kwd><kwd>neuronavigation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brovkina A.F. [Diseases of the orbit]. Diseases of the orbit. Moscow, Medicine, 1993 (in Russ).</mixed-citation><mixed-citation xml:lang="en">Brovkina A.F. [Diseases of the orbit]. Diseases of the orbit. Moscow, Medicine, 1993 (in Russ).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fichter N., Guthoff R., Schittkowski M. Orbital decompression in thyroid eye disease. ISRN Ophtalmology. 2012;2012:1‑12. DOI: 10.5402/2012/739236</mixed-citation><mixed-citation xml:lang="en">Fichter N., Guthoff R., Schittkowski M. Orbital decompression in thyroid eye disease. ISRN Ophtalmology. 2012;2012:1‑12. DOI: 10.5402/2012/739236</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Naik M., Nair A., Gupta A., Kamal S. Minimally invasive surgery for thyroid eye disease. Indian J Ophalmol. 2015;63:847‑853. DOI:10.4103/0301‑4738.171967</mixed-citation><mixed-citation xml:lang="en">Naik M., Nair A., Gupta A., Kamal S. Minimally invasive surgery for thyroid eye disease. Indian J Ophalmol. 2015;63:847‑853. DOI:10.4103/0301‑4738.171967</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bartalena L., Fatourechi V. Extrathyroidal manifestations of Graves’ disease: a 2014 update. J Endocrinol Invest. 2014;37:691–700. DOI: 10.1530/EJE‑07‑0666</mixed-citation><mixed-citation xml:lang="en">Bartalena L., Fatourechi V. Extrathyroidal manifestations of Graves’ disease: a 2014 update. J Endocrinol Invest. 2014;37:691–700. DOI: 10.1530/EJE‑07‑0666</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Goldberg R. Advances in surgical rehabilitation in thyroid eye disease. Thyriod. 2008;18(9):989‑995. DOI:10.1089/thy.2008.0033</mixed-citation><mixed-citation xml:lang="en">Goldberg R. Advances in surgical rehabilitation in thyroid eye disease. Thyriod. 2008;18(9):989‑995. DOI:10.1089/thy.2008.0033</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hill R., Czyz C., Bersani T. Transcaruncular medial wall orbital decompression: an effective approach for patients with unilateral Graves Opthalmopathy. The scientific world journal. 2012; 2012:1‑6. DOI: 10.11002012312361</mixed-citation><mixed-citation xml:lang="en">Hill R., Czyz C., Bersani T. Transcaruncular medial wall orbital decompression: an effective approach for patients with unilateral Graves Opthalmopathy. The scientific world journal. 2012; 2012:1‑6. DOI: 10.11002012312361</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Remulla H., Gliklich R., Metson R.,Rubin P. Delayed orbital infection after endoscopic orbital decompression for dysthyroid orbithopathy. Ophtalmology. 2000;107(5):947‑950. DOI: 10.1016/j.ijom.2009.10.011</mixed-citation><mixed-citation xml:lang="en">Remulla H., Gliklich R., Metson R.,Rubin P. Delayed orbital infection after endoscopic orbital decompression for dysthyroid orbithopathy. Ophtalmology. 2000;107(5):947‑950. DOI: 10.1016/j.ijom.2009.10.011</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fadeev V.V. К 170‑летию описания Роберта Грейвса. [To the 170th anniversary of Robert Graves description. [Clinical and experimental thyroidology]. Klinicheskaya i eksperimental’naya tireoidologiya. 2006;2(1):5‑8. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Fadeev V.V. К 170‑летию описания Роберта Грейвса. [To the 170th anniversary of Robert Graves description. [Clinical and experimental thyroidology]. Klinicheskaya i eksperimental’naya tireoidologiya. 2006;2(1):5‑8. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Levchenko OV, Shalumov AZ, Krylov VV. [Plasticity of frontal‑orbital localization defects with the use of frameless navigation]. Plastika defektov lobnoglaznichnoy lokalizatsii s ispol’zovaniem bezramnoy navigatsii. [Neurosurgery]. Neyrokhirurgiya. 2010;3:30‑35. (in Russ.).</mixed-citation><mixed-citation xml:lang="en">Levchenko OV, Shalumov AZ, Krylov VV. [Plasticity of frontal‑orbital localization defects with the use of frameless navigation]. Plastika defektov lobnoglaznichnoy lokalizatsii s ispol’zovaniem bezramnoy navigatsii. [Neurosurgery]. Neyrokhirurgiya. 2010;3:30‑35. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bartalena L., Fatourechi V. Extrathyroidal manifestations of Graves’ disease: a 2014 update. J Endocrinol Invest. 2014;37:691–700. DOI:10.1007/s40618‑014‑0097‑2</mixed-citation><mixed-citation xml:lang="en">Bartalena L., Fatourechi V. Extrathyroidal manifestations of Graves’ disease: a 2014 update. J Endocrinol Invest. 2014;37:691–700. DOI:10.1007/s40618‑014‑0097‑2</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Mehta P., Durrani O. Outcome of deep lateral wall rimsparing orbital decompression in thyroid‑associated orbitopathy: a new technique and results of a case series. Orbit. 2011;30(6):265–268. DOI:10.3109/01676830.2011.603456</mixed-citation><mixed-citation xml:lang="en">Mehta P., Durrani O. Outcome of deep lateral wall rimsparing orbital decompression in thyroid‑associated orbitopathy: a new technique and results of a case series. Orbit. 2011;30(6):265–268. DOI:10.3109/01676830.2011.603456</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Leone C., Piest K., Newman R. // Medial and lateral wall decompression for thyroid ophthalmopathy. Am J Ophthalmol. 1989; 108(2):160—166. PMID:2757096</mixed-citation><mixed-citation xml:lang="en">Leone C., Piest K., Newman R. // Medial and lateral wall decompression for thyroid ophthalmopathy. Am J Ophthalmol. 1989; 108(2):160—166. PMID:2757096</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Baldeschi L., MacAndie K., Hintschich C. The removal of the deep lateral wall in orbital decompression: its contribution to exophthalmos reduction and influence on consecutive diplopia. Am J Ophthalmol. 2005;140:642–647. DOI: 10.1016/2005.04.023</mixed-citation><mixed-citation xml:lang="en">Baldeschi L., MacAndie K., Hintschich C. The removal of the deep lateral wall in orbital decompression: its contribution to exophthalmos reduction and influence on consecutive diplopia. Am J Ophthalmol. 2005;140:642–647. DOI: 10.1016/2005.04.023</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">McCord C. Orbital decompression for Graves’ disease: exposure through lateral canthal and inferior fornix incision. Ophthalmology. 1981;88:533—541. DOI: 10.4236/ss.2011.23031</mixed-citation><mixed-citation xml:lang="en">McCord C. Orbital decompression for Graves’ disease: exposure through lateral canthal and inferior fornix incision. Ophthalmology. 1981;88:533—541. DOI: 10.4236/ss.2011.23031</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Dubin M., Tabaee A., Scruggs J. Image‑guided endoscopic orbital decompression for Graves’ orbitopathy. Ann OtolRhinol Laryngol. 2008;117(3):177—185. PMID: 18444477</mixed-citation><mixed-citation xml:lang="en">Dubin M., Tabaee A., Scruggs J. Image‑guided endoscopic orbital decompression for Graves’ orbitopathy. Ann OtolRhinol Laryngol. 2008;117(3):177—185. PMID: 18444477</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Graham S., Brown C., Carter K. Medial and lateral orbital wall surgery for balanced decompression in thyroid eye disease. Laryngoscope. 2003;113(7):1206—1209. DOI:10.1097/00005537‑200307000‑00017</mixed-citation><mixed-citation xml:lang="en">Graham S., Brown C., Carter K. Medial and lateral orbital wall surgery for balanced decompression in thyroid eye disease. Laryngoscope. 2003;113(7):1206—1209. DOI:10.1097/00005537‑200307000‑00017</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Silver R., Harrison A., Goding G. Combined endoscopic medial and external lateral orbital decompression for progressive thyroid eye disease. Otolaryngol Head Neck Surg. 2006;134(2):260–266. DOI:10.1097/00005537‑200307000‑00017</mixed-citation><mixed-citation xml:lang="en">Silver R., Harrison A., Goding G. Combined endoscopic medial and external lateral orbital decompression for progressive thyroid eye disease. Otolaryngol Head Neck Surg. 2006;134(2):260–266. DOI:10.1097/00005537‑200307000‑00017</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Millar M., Maloof A. The application of stereotactic navigation surgery to orbital decompression for thyroid‑associated orbitopathy. Eye. 2009;23:1565‑1571. DOI:10.1038/2009.24</mixed-citation><mixed-citation xml:lang="en">Millar M., Maloof A. The application of stereotactic navigation surgery to orbital decompression for thyroid‑associated orbitopathy. Eye. 2009;23:1565‑1571. DOI:10.1038/2009.24</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
