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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2018-1-58-63</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-544</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL &amp; EXPERIMENTAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Изменение офтальмобиометрических параметров при миопии и гиперметропии под действием циклоплегии</article-title><trans-title-group xml:lang="en"><trans-title>Change in the Ophthalmobiometric Parameters in Myopia and Hyperopia under the Influence of Cycloplegia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнян</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarutta</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики</p></bio><bio xml:lang="en"><p>MD professor, head of the refraction pathology, binocular vision and ophthalmoergonomics department</p></bio><email xlink:type="simple">arutyunyansg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Милаш</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Harutyunyan</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики</p></bio><bio xml:lang="en"><p>Postgraduate</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханджян</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Milash</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, научный сотрудник отдела патологии сетчатки</p></bio><bio xml:lang="en"><p>Ophthalmologist of the refraction pathology, binocular vision and ophthalmoergonomics department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходжабекян</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khandzhyan</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, руководитель лаборатории офтальмоэргономикии оптометрии</p></bio><bio xml:lang="en"><p>Khandzhyan Anush Tigranovna Researcher of the Retinal Pathology Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Проскурина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodzhabekyan</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Khodzhabekyan Narine Vladimirovna Head of the Ophthalmoergonomics and Optometry Laboratory</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Helmholtz Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>25</day><month>03</month><year>2018</year></pub-date><volume>15</volume><issue>1</issue><fpage>58</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арутюнян С.Г., Милаш С.В., Ханджян А.Т., Ходжабекян Н.В., Проскурина О.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Арутюнян С.Г., Милаш С.В., Ханджян А.Т., Ходжабекян Н.В., Проскурина О.В.</copyright-holder><copyright-holder xml:lang="en">Tarutta E.P., Harutyunyan S.G., Milash S.V., Khandzhyan A.T., Khodzhabekyan N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/544">https://www.ophthalmojournal.com/opht/article/view/544</self-uri><abstract><p>РЕЗЮМЕ Цель: сравнение некоторых офтальмобиометрических параметров в естественных и циклоплегических условиях при миопии и гиперметропии. Пациенты и методы. Были оценены биометрические параметры глаза (глубина передней камеры, толщина хрусталика и длина ПЗО) до и после циклоплегии (1% Cyclopentolate hydrochloride дважды) на 244 глазах с миопической и гиперметропической рефракцией у 122 пациентов в возрасте 5–32 лет (в среднем 17,8 ± 1,2). Биометрические параметры исследовали с помощью анализатора оптической системы глаза Galilei G6 (Ziemer Ophthalmic Systems AG 6.0.6). Толщину хори-оидеи измеряли c использованием спектрального оптического когерентного томографа SD-OCT с длиной волны 800 нм (Nidek RS-3000 Retina Scan Advance) в 20 глазах 10 пациентов в возрасте 11 ± 1,3 года из обследованной группы. Результаты. Глубина передней камеры и длина ПЗО как с узким зрачком, так и при циклоплегии в миопических глазах была достоверно выше, чем в гиперметропических (р &lt; 0,05 для ГПК, р &lt; 0,01 для ПЗО), а толщина хрусталика практически не отличалась. Расстояние от задней поверхности роговицы до центра хрусталика при миопии достоверно было больше, чем при гиперметропии, соответственно 5,62 ± 0,02 и 5,29 ± 0,01 мм (р &lt; 0,01). Однако коэффициент Lowе (————————) при миопии был достоверно ниже (0,219 ± 0,001 и 0,238 ± 0,001 соответственно) за счет большей длины ПЗО. После циклоплегии как в миопических, так и в гиперметропических глазах ГПК увеличивался: при миопии — в среднем на 0,12 мм, при гиперметропии — на 0,14 мм, и соответственно уменьшалась толщина хрусталика. Коэффициент Lowe в обоих случаях увеличивался на 0,04 мм. Интересные изменения обнаружились относительно длины ПЗО: в условиях циклоплегии имеет место ее уменьшение на 30 мкм в глазах с миопией (р &gt; 0,05) и на 40 мкм — с гиперметропией (р &lt; 0,01). Заключение. В условиях циклоплегии по сравнению с действу-ющей аккомодацией увеличивается глубина передней камеры, уменьшается толщина хрусталика, центр хрусталика несколько отодвигается кзади и уменьшается длина ПЗО. Выявленные изменения длины ПЗО могут быть связаны с изменением положения слоя пигментного эпителия из-за изменений толщины хориоидеи при разных состояниях аккомодации. В данной работе не удалось выявить достоверных изменений толщины хориоидеи под действием циклоплегиков</p></abstract><trans-abstract xml:lang="en"><p>Purpose: comparison of some ophthalmobiometric parameters in natural and cycloplegic conditions in myopia and hypermetropia.Material and methods: eyes biometric parameters were examined (the depth of the anterior chamber, the lens thickness and AL)before and after cycloplegia (1% Cyclopentolate hydrochloride — 2 times) in 244 eyes with myopic and hyperopic refraction in 122patients aged 5–32 years. Biometric parameters were examined on the Galilei G6 optical system analyzer (Ziemer Ophthalmic SystemsAG 6.0.6). The thickness of the choroid was measured with a spectral optical coherent tomograph (SD-OCT wavelength 800 nm) of Nidek RS-3000 Retina Scan Advance in 20 eyes of 10 patients aged 11 ± 1.3 years from the examined group before and 40 minutes after double injection of 1% Cyclopentolate hydrochloride. Results: the depth of anterior chamber and the axial, both in the narrow pupil and under the cycloplegia, are significantly higher in the myopic eyes than in the hyperopic eyes (p &lt; 0.05 for ACD and p &lt; 0.01 for AL), and the lens thickness is practically does not differ. In absolute terms, the position of irido-lens diaphragm, i.e. distance from the posterior surface of the cornea to the center of the lens in myopia group was significantly higher than with hyperopia respectively, of 5.62 ± 0.02 mm of 5.29 ± 0.01 mm (p &lt; 0.01). However, the coefficient Lowе ((ACD + 1/2LT)/AL) in myopia was significantly lower (of 0.219 ± 0.001 and 0,238 ± 0,001, respectively) is due to the greater of the AL. After cycloplegia, in both myopic and hyperopic eyes, DAC increases: in myopia, on average, 0.12 mm, with hyperopia — by 0.14 mm, and accordingly the thickness of the lens decreases. The coefficient Lowe in both cases is increased by 0,04 mm. Interesting changes were observed in the length of AL: under conditions of cycloplegia, it decreased by 0.03 mm (30 microns) in eyes with myopia (p &gt; 0.05) and by 40 microns (0.04 mm) with hyperopia (p &lt; 0.01). Conclusion: In cyclopegic condidions, as compared to the existing accommodation, increasing the depth of the anterior chamber decreased the thickness of the lens center of the lens somewhat extended posteriorly and decreases the axial length. The revealed changes in the AL can be associated with a change in the position of the pigment epithelium layer due to changes in the thickness of the choroid under different accommodation conditions. The significant changes in the thickness of the choroid the influence of cycloplegia was not proved in this study.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ПЗО</kwd><kwd>толщина хориоидеи</kwd><kwd>хрусталик</kwd><kwd>коэффициент Lowe</kwd><kwd>циклоплегия</kwd><kwd>гиперметропия</kwd><kwd>миопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>AL</kwd><kwd>thickness of the choroid</kwd><kwd>lens</kwd><kwd>coefficient Lowе</kwd><kwd>cycloplegia</kwd><kwd>hyperopia</kwd><kwd>myopia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gwiazda .J, Thorn F., Bauer J., Held R. Myopic children show insufficient accommodative response to blur. 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