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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2018-2S-254-260</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-657</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОЧЕЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OTHER</subject></subj-group></article-categories><title-group><article-title>Соответствие данных индоцианин-зеленой ангиографии и ОКТ-ангиографии в диагностике неоваскуляризации при хронической центральной серозной хориоретинопатии</article-title><trans-title-group xml:lang="en"><trans-title>Accordance of Indocyanine Green Angiography and Optical Coherence Tomography Angiography in Visualization of Neovascularization Associated with Chronic Central Serous Chorioretinopathy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5191-3385</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Педанова</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Pedanova</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, научный сотрудник,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>PhD, researcher,</p><p>Beskudnikovskiy blvd, 59а, Moscow, 127486</p></bio><email xlink:type="simple">elenamntk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4348-3973</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клепинина</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Klepinina</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, младший научный сотрудник,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>PhD, junior researcher,</p><p>Beskudnikovskiy blvd, 59а, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4528-1446</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буряков</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Buryakov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, младший научный сотрудник,</p><p>Бескудниковский бульвар, 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>PhD, junior researcher,</p><p>Beskudnikovskiy blvd, 59а, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ «МНТК “Микрохирургия глаза” имени академика С. Н. Федорова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>28</day><month>07</month><year>2018</year></pub-date><volume>15</volume><issue>2S</issue><fpage>254</fpage><lpage>260</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Педанова Е.К., Клепинина О.Б., Буряков Д.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Педанова Е.К., Клепинина О.Б., Буряков Д.А.</copyright-holder><copyright-holder xml:lang="en">Pedanova E.K., Klepinina O.B., Buryakov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/657">https://www.ophthalmojournal.com/opht/article/view/657</self-uri><abstract><sec><title>Цель</title><p>Цель: сравнить информативность и согласованность данных индоцианин-зеленой ангиографии (ИЗАГ) и ОКТ-ангиографии (ОКТ-А) в диагностике неоваскуляризации при хронической центральной серозной хориоретинопатии (ЦСХ).</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. В исследование включен двадцать один пациент (21 глаз) в возрасте 51,0 ± 8,4 года с диагнозом хроническая ЦСХ и предполагаемая субретинальная неоваскуляризация (СНМ) — признак «двойного слоя» на сканах ОКТ. Для выявления СНМ проводили ИЗАГ и ОКТ-ангиографию. Анализ снимков выполняли двумя экспертами.</p></sec><sec><title>Результаты</title><p>Результаты. Обе методики показали сходные результаты. СНМ обнаружена методом ИЗАГ у 11 пациентов из 21, а методом ОКТ-А у 13 из 21, статистически значимая разница отсутствовала (p = 0,74, хи-квадрат). СНМ не была выявлена при проведении ИЗАГ у 10 пациентов из 21, ОКТ-А — у 8 из 21 (p = 0,69). Однако при попарном анализе снимков у каждого конкретного пациента согласованность двух методов по обнаружению СНМ присутствовала только у 8 пациентов из 21. Согласованность результатов при отсутствии выявления СНМ была у 6 пациентов, в основном в случаях свежего рецидива ЦСХ. У трети пациентов (7 из 21) данные методик расходились. На ОКТ-А визуализация СНМ затруднена при блокировании субретинальным депозитом и пигментом. В случае диффузной атрофии пигментного эпителия сосудистая сеть не видна на снимках ИЗАГ, но хорошо визуализируется на ОКТ-А.</p></sec><sec><title>Заключение</title><p>Заключение. Информативность двух методик в диагностике СНМ при хронической ЦСХ является сходной. Для интерпретации данных следует принимать во внимание состояние сетчатки и пигментного эпителия. ОКТ–ангиография более четко показывает контур сосудистой сети, особенно в случае диффузной эпителиопатии. Об активности неоваскуляризации и рецидивировании точек просачивания лучшее представление дает ИЗАГ. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to compare informativity and accordance of indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCT-A) data in visualization of neovascularization associated with chronic central serous chorioretinopathy. Patients and</p></sec><sec><title>Methods</title><p>Methods. Twenty one eye of 21 patients (aged 51.0 ± 8.4 years old) with chronic central serous chorioretinopathy (CSR) and assumed choroidal neovascularisation (CNV) with «double layer» sign on optical coherence tomography scans were enrolled in this study. ICGA on Spectralis HRA+OCT, (Heidelberg Engeneering, Germany) and OCT-A on RTVue XR Avanti (Optovue, USA) were performed to evaluate CNV. The assessment of obtained pictures was examined by two experts.</p></sec><sec><title>Results</title><p>Results. Both diagnostic methods have shown similar results. CNV has been revealed in 11 of 21 eyes by ICGA imaging while OCT-A confirmed neovascularization in 13 eyes — with no statistical difference between methods (p = 0.74, χ2). CNV has not been diagnosed in 10 cases by ICGA and in 8 cases by OCT-A (p = 0.69). However, the consistency of the two methods in CNV evaluation while pairwise comparison of angiography data has been confirmed only in 8 eyes. The absence of CNV has been confirmed in 6 eyes — mostly in patients with CSR recurrence. One third of patients (7 of 21 eyes) have not shown consistence of two methods. The OCT-A visualization of CNV could be poor because of subretinal deposits and pigment-related signal blocking. In cases of diffuse retinal pigment epithelium atrophy the neovascular network cannot been seen on ICGA images while well visualized on OCT-A.</p></sec><sec><title>Conclusion</title><p>Conclusion. The informativity of ICGA and OCT-A in visualization of neovascularization associated with chronic central serous chorioretinopathy is similar. For the best data interpretation the condition of neurosensory retina and pigment retinal epitheluium should be taken into account. OCT-A is more preferable in cases of diffuse epitheliopathy, while the neovascularization activity and leakage points is better seen on ICGA. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая центральная серозная хориоретинопатия</kwd><kwd>ОКТ-ангиография</kwd><kwd>ангиография с индоцианином зеленым</kwd><kwd>признак «двойного слоя»</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic central serous chorioretinopathy</kwd><kwd>OCT-angiography</kwd><kwd>Indocyanine Green Angiography</kwd><kwd>double layer sign</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дога А.В., Качалина Г.Ф., Клепинина О.Б. Центральная серозная хориоретинопатия: современные аспекты диагностики и лечения: руководство для врачей/ А.В. Дога, Г.Ф. Качалина, О.Б. Клепинина. Москва: Офтальмология; 2017:226. [Doga A.V., Kachalina G.F., Klepinina O.B. 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