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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ophthalmology</journal-id><journal-title-group><journal-title xml:lang="ru">Офтальмология</journal-title><trans-title-group xml:lang="en"><trans-title>Ophthalmology in Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1816-5095</issn><issn pub-type="epub">2500-0845</issn><publisher><publisher-name>Ophthalmology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18008/1816-5095-2019-2-159-162</article-id><article-id custom-type="elpub" pub-id-type="custom">ophthalmology-948</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Визуализация решетчатой пластинки склеры с помощью оптической когерентной томографии. Возможности и перспективы диагностики. Обзор</article-title><trans-title-group xml:lang="en"><trans-title>Visualization of the Lamina Cribrosa of Sclera Using Optical Coherence Tomography. The Opportunities and Prospects for Diagnostics (Review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куренков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurenkov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор,</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>МD, рrofessor,</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клюганов</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Klyuganov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог,</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Ophthalmologist,</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><email xlink:type="simple">kluger3@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог,</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Ophthalmologist,</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чиненова</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chinenova</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-офтальмолог,</p><p>Рублевское шоссе, 48/1, Москва, 121609</p></bio><bio xml:lang="en"><p>Ophthalmologist,</p><p>Rublevskoe highway, 48, Moscow, 121609</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коновалов</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Konovalov</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, руководитель Центра,</p><p>ул. 3-я Тверская-Ямская, 56/6, Москва, 125047</p></bio><bio xml:lang="en"><p>MD, professor, Head of Konovalov eye center,</p><p>Tverskaya-Yamskaya str., 56/6, Moscow, 125047</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пожарицкий</surname><given-names>М. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Pozharitsky</surname><given-names>M. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий анестезиологическим отделением,</p><p>Волоколамское ш., 91, Москва, 125371</p></bio><bio xml:lang="en"><p>MD, professor,</p><p>Volokolamskoye highway, 91, Moscow, 125371</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Офтальмологическая клиника доктора Куренкова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ophthalmology Clinic of Dr. Kurenkov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Офтальмологический центр Коновалова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Konovalov eye center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Академия постдипломного образования ФГБУ ФНКЦ ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academy of postgraduate education under FSBU FSCC of FMBA of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>26</day><month>06</month><year>2019</year></pub-date><volume>16</volume><issue>2</issue><fpage>159</fpage><lpage>162</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Куренков В.В., Клюганов В.С., Кузнецова Н.В., Чиненова К.В., Коновалов М.Е., Пожарицкий М.Д., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Куренков В.В., Клюганов В.С., Кузнецова Н.В., Чиненова К.В., Коновалов М.Е., Пожарицкий М.Д.</copyright-holder><copyright-holder xml:lang="en">Kurenkov V.V., Klyuganov V.S., Kuznetsova N.V., Chinenova K.V., Konovalov M.E., Pozharitsky M.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ophthalmojournal.com/opht/article/view/948">https://www.ophthalmojournal.com/opht/article/view/948</self-uri><abstract><p>Решетчатая пластинка склеры представляет собой многослойную дифференцированную структуру, состоящую из пластов соединительной ткани, представленной коллагеном различного типа. Соотношение коллагеновых волокон I, II и IV типов, а также белка эластина обеспечивает опорные и эластические свойства решетчатой пластинки, имеющей ограниченную резистентность. Повышенное внутриглазное давление на фоне инволюционных изменений состава соединительной ткани решетчатой пластинки приводит к ее деформации, компрессии нервных волокон, проходящих через отверстия в решетчатой пластинке и, как следствие, к нарушению аксоплазматического тока. Современные оптические когерентные томографы высокого разрешения позволяют визуализировать границы решетчатой пластинки, а стандартное программное обеспечение, интегрированное в каждый прибор, дает возможность измерять параметры решетчатой пластинки. Проблемой остается визуализация решетчатой пластинки на ранних стадиях глаукомы из-за выраженности преламинарной ткани и экранирования поверхности решетчатой пластинки. Обзор содержит результаты ряда исследований различных офтальмологов. Обнаружена зависимость таких показателей решетчатой пластинки, как глубина, толщина, угол наклона и кривизна, от колебаний внутриглазного давления и стадии глаукомного процесса. Данные исследования подтверждают возможность визуализации решетчатой пластинки, открывают перспективы для изучения патогенеза глаукомы и расширяют возможности поиска новых методов лечения глаукомной оптической нейропатии, основываясь на патогенетических аспектах. Однако малое количество статей по данной тематике, встречаемое в литературе, небольшая выборка исследуемых групп в большинстве работ требуют дальнейшего изучения вопроса визуализации решетчатой пластинки при помощи оптической когерентной томографии для последующего внедрения в практическую офтальмологию.</p></abstract><trans-abstract xml:lang="en"><p>The lamina cribrosa of the sclera is a multilayer structure consisting of layers of connective tissue represented by collagen of various types. The ratio of collagen fibers I, II and IV types, as well as elastin protein provide support and elastic properties of the lamina cribrosa. Increased intraocular pressure on the background of involutional changes in the composition of the connective tissue of the lamina cribrosa leads to deformation of the latter, compression of nerve fibers passing through the holes in the lamina cribrosa and violation of the axoplasmic current. Modern high-resolution optical coherence tomographs allow to visualize the confines of the lamina cribrosa, and the standard software integrated into each device allows to measure the parameters of the lamina cribrosa. The visualization of the lamina cribrosa in the early stages of glaucoma due to the severity of the pre-laminar tissue and the screening of the surface of the lamina cribrosa is still a problem. The presented review contains the results of studies of various ophthalmologists from different countries. The dependence of such parameters of the lamina cribrosa as depth, thickness, angle of inclination and curvature on the increased of intraocular pressure and the stage of glaucoma process was found. These studies confirm the possibility of visualization of the lamina cribrosa, open prospects in the study of the pathogenesis of glaucoma and expand the possibilities in the search for new methods of treatment of glaucoma optical neuropathy based on pathogenetic aspects. However, a small number of articles on this subject, found in the literature, and a small sample of the study groups in most works require further study of the visualization of the lamina cribrosa using optical coherence tomography.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>решетчатая пластинка</kwd><kwd>оптическая когерентная томография</kwd><kwd>внутриглазное давление</kwd><kwd>глаукомная оптическая нейропатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lamina cribrosa</kwd><kwd>optical coherence tomography</kwd><kwd>intraocular pressure</kwd><kwd>glaucoma optical neuropathy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tham Y.C., Li X., Wong T.Y., Quigley H.A., Aung T., Cheng C.Y. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. J Ophthalmology. 2014 Nov; 121(11):2081–2090. 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