Clinical polymorphism of endocrine ophthalmopathy
https://doi.org/10.18008/1816-5095-2012-2-33-38
Abstract
Purpose: to analyze clinical polymorphism of endocrine ophthalmopathy in patients with Graves’ disease.
Methods: Clinical and radiological data of 18 cases with clinical manifestations of lacrimal gland increase were analyzed and compared with data retrieved from 50 patients without increasing of lacrimal gland.
Results: the characteristics of clinical manifestations of endocrine ophthalmopathy with lacrimal gland increase were presented. this form differs, as the organ of the target, along with orbital fat and/or eye muscles becomes the glandula lacrimalis. A correlation between fact involving, on the one hand, and the intensity and severity of the autoimmune process in orbit, on the other hand were identified.
Conclusion: Involvement of this secretion organ in the autoimmune process makes the clinical course of endocrine ophthalmopa-
thy more complicated, and leads to eye dry syndrome creation.
About the Authors
V. G. Likhvantseva
117192 Москва, Ломоносовский проспект, 31, корп. 5;
Russian Federation
Russian Federation
T. N. Safonova
Russian Federation
N. Y. Sviridenko
Russian Federation
K. I. Tabeeva
Russian Federation
O. A. Gontyurova
Russian Federation
V. A. Vygodin
Russian Federation
References
1. Бровкина А. Ф. // Эндокринная офтальмопатия. — М.: ГЕОТАР — МЕД., 2004. — С. 39‐40.
2. Табеева К. И Клиническое течение эндокринной офтальмопатии после хи- рургического лечения болезни Грейвса. Дисс....канд мед наук. — М., 2010.
3. Шеремета М. С. Эндокринная офтальмопатия: диагностика, особенности те- чения после радиойодтерапии болезни Грейвса. Дисс.... канд. мед наук. — М., 2010.
4. Cawood T, Moriarty P. And O’Shea. Recent developments in thyroid eye disease // BMJ. — 2004. — Vol. 329. — P. 385‐390.
5. Gorman CA. The measurement of change in Graves’ ophthalmopathy // Thy- roid. — 1998. — Vol. 8. — P. 539‐543.
6. Graves’ Orbitopahy. / Ed. W. M. Wiersinga, G. J. Kahaly. Karger, 2010. Basel — Lon- don. — P. 260.
7. Heufelder A., Joba W. Thyroid‐associated eye disease // Strabismus. — 2000. — No 2 — P. 101‐111.
8. Kendall‐Taylor P, Perros P. Clinical presentation of thyroid‐associated orbitopa- hy // Thyroid. — 1998. — Vol. 8. — P. 427‐428.
9. Perros P, Crombie A, Kendall‐Taylor P. Natural history of thyroid‐associated orbi- topahy // Clin Endocrinol (Oxf). — 1995. — Vol. 42. — P. 45‐50.
10. Werner SC. Modification of the classification of the eye changes of Graves’ dis- ease // Am. J. Ohthalmol. 1977. — Vol. 83. — P. 725‐727.
11. Wiersinga W. M., Kahaly G. J. Graves’ orbitopahy. A multidisciplinary approach // Basel (Switzerland), 2007. — P. 1‐23.
12. Yoshikawa K., Higashide T.& Nakase Y. Role of muscle enlargement in clinical profile of dysthyroid ophthalmopathy // Jpn J Ophthalmol. — 1991. — Vol. 35. — P. 175‐181.
Review
For citations:
Likhvantseva V.G., Safonova T.N., Sviridenko N.Y., Tabeeva K.I., Gontyurova O.A., Vygodin V.A. Clinical polymorphism of endocrine ophthalmopathy. Ophthalmology in Russia. 2012;9(2):33-38. (In Russ.) https://doi.org/10.18008/1816-5095-2012-2-33-38
Views:
1365
Email this article 