Assessment of Risk Factors for the Development of Late Intraocular Lens Dislocation
https://doi.org/10.18008/1816-5095-2021-1-103-109
Abstract
Dislocation of intraocular lens is a serious complication of phacoemulsification with implantation of intraocular lens. Among the causes of early dislocation of intraocular lens intraoperative complications predominate, as well as various form of their mixed fixation. In the late postoperative period, dislocation of the capsular bag-intraocular lens complex mainly occurs, the main reasons for which are the zonular weakness and the failure of the capsular bag support or its fibrosis.
Purpose: to assess the influence of various factors on the development of late IOL dislocation (both in the capsular bag and without it) requiring surgical correction.
Patientes and methods. The study included 78 patients (78 eyes) who were underwent surgical treatment of varying degree of IOL dislocation from October 2018 to April 2020. The control group consisted of 62 patients recruited for surgical treatment of cataract at the same period. The main factors for assessment were the following: axial myopia (≥26 mm), previous vitreoretinal surgery, recurrent uveitis, primary glaucoma, retinitis pigmentosa, and the use of the capsular tension ring during phacoemulsification.
Results. Among the factors studied, the following risk factors of late IOL dislocation were revealed: age, gender, the presence of pseudoexfoliation syndrome, axial myopia, primary glaucoma, implantation of the capsular tension ring. Conclusion. Phacoemulsification is the standard surgical treatment of cataract. However, in patients with potential risk factors of developing IOL dislocation, surgeons should consider the use of additional IOL fixation.
About the Authors
V. V. PotemkinRussian Federation
Potemkin Vitaly V. – MD, Assistant Professor Ophthalmology department, ophthalmologist
Lev Tolstoy str., 6–8, build. 16, Saint Petersburg, 197089,
Uchebniy lane, 5, Saint Petersburg, 194354
S. Yu. Astakhov
Russian Federation
Astakhov Sergey Yu. – MD, Professor, head of Ophthalmology department
Lev Tolstoy str., 6–8, build. 16, Saint Petersburg, 197089
E. V. Goltsman
Russian Federation
Goltsman Elena V. – ophthalmologist
Uchebniy lane, 5, Saint Petersburg, 194354
Syao Yu. Van
Russian Federation
Van Syao Yuan – postgraduate of Ophthalmology department
Lev Tolstoy str., 6–8, build. 16, Saint Petersburg
References
1. Olson R.J., Mamalis N., Werner L., Apple D.J. Cataract treatment in the beginning of the 21st century. American Journal of Ophthalmology. 2003;136(1):146–154. DOI: 10.1016/S0002-9394(03)00226-5
2. Boke W.R., Kruger H.C. Causes and management of posterior chamber lens displacement. J Am Intraocul Implant Soc. 1985;11(2):179–184.
3. Gimbel H.V., Condon G.P., Kohnen T., Olson R.J., Halkiadakis I. Late in-the-bag intraocular lens dislocation: incidence, prevention, and management. J Cataract Refract Surg. 2005;31(11):2193–2204. DOI: 10.1016/j.jcrs.2005.06.053
4. Hayashi K., Hirata A., Hayashi H. Possible predisposing factors for in-the-bag and out-of-the-bag intraocular lens dislocation and outcomes of intraocular lens exchange surgery. Ophthalmology. 2007;114(5):969–975. DOI: 10.1016/j.ophtha.2006.09.017
5. Oh S.Y., Lee S.J., Park J.M. Comparison of surgical outcomes of intraocular lens refixation and intraocular lens exchange with perfluorocarbon liquid and fibrin glueassisted sutureless scleral fixation. Eye (Lond). 2015;29(6):757–763. DOI: 10.1038/eye.2015.22
6. Kratz R.P., Mazzocco T.R., Davidson B., Colvard D.M. The Shearing intraocular lens: a report of 1,000 cases. J Am Intraocul Implant Soc. 1981;7(1):55–57.
7. Stark W.J. Jr., Maumenee A.E., Datiles M. Intraocular lenses: complications and visual results. Trans Am Ophthalmol Soc. 1983;81:280–309.
8. Stark W.J. Jr., Worthen D.M., Holladay J.T. The FDA report on intraocular lenses. Ophthalmology. 1983;90(4):311–317.
9. Davis D., Brubaker J., Espandar L. Late in-the-bag spontaneous intraocular lens dislocation: evaluation of 86 consecutive cases. Ophthalmology. 2009;116(4):664–670. DOI: 10.1016/j.ophtha.2008.11.018
10. Gross J.G., Kokame G.T., Weinberg D.V. In-the-bag intraocular lens dislocation. Am J Ophthalmol. 2004;137(4):630–635. DOI: 10.1016/j.ajo.2003.10.037
11. Ganesh S.K., Sen P., Sharma H.R. Late dislocation of in-the-bag intraocular lenses in uveitic eyes: An analysis of management and complications. Indian J Ophthalmol. 2017;65(2):148–154. DOI: 10.4103/ijo.IJO_938_16
12. Gul A., Duran M., Can E. Surgical management of intraocular lens dislocations. Arq Bras Oftalmol. 2015;78(5):313–317. DOI: 10.5935/0004-2749.20150082
13. Liu E., Cole S., Werner L., Hengerer F. Pathologic evidence of pseudoexfoliation in cases of in-the-bag intraocular lens subluxation or dislocation. Journal of Cataract & Refractive Surgery. 2015;41(5):929–935. DOI: 10.1016/j.jcrs.2014.08.037
14. Lorente R., Rojas V., Vazquez de Parga P. Management of late spontaneous in-thebag intraocular lens dislocation: Retrospective analysis of 45 cases. J Cataract Refract Surg. 2010;36:1270–1282. DOI: 10.1016/j.jcrs.2010.01.035
15. Davison J.A. Capsule contraction syndrome. J. Cataract Refract Surg. 1993;19(5):582– 589.
16. Werner D.S., Pandey S.K., Apple D.J. Anterior capsule opacification: correlation of pathologic findings with clinical sequelae. Ophthalmology. 2001;108:1675–1681. DOI: 10.1016/s0161-6420(99)00088-3
17. Matsumoto M., Yamada K., Uematsu M. Spontaneous dislocation of in-the-bag intraocular lens primarily in cases with prior vitrectomy. European Journal of Ophthalmology. 2012;22(3):363–367. DOI: 10.5301/ejo.5000046
18. Shigeeda M., Nagahara S. Kato D. Spontaneous posterior dislocation of intraocular lenses fixated in the capsular bag. Journal of Cataract and Refractive Surgery. 2002;28(9):1689–1693. DOI: 10.1016/s0886-3350(01)01178-6
19. Zech J.-C., Tanniere P., Denis P., and Trepsat C. Posterior chamber intraocular lens dislocation with the bag. Journal of Cataract and Refractive Surgery. 1999;25(8):1168–1169.
20. Brilakis H.S., Lustbader J.M. Bilateral dislocation of inthe-bag posterior chamber intraocular lenses in a patient with intermediate uveitis. Journal of Cataract and Refractive Surgery.2003;29(10):2013–2014. DOI: 10.1016/s08863350(03)00226-8
21. Marın I. M., Tejero R. T., Dominguez M. F., and Gutierrez E. M., Ocular injuries in midfacial fractures. Orbit.1998;17(1):41–46. DOI: 10.1076/orbi.17.1.41.7950
22. Yamazaki S., Nakamura K., Kurosaka D., Intraocular lens subluxation in a patient with facial atopic dermatitis. Journal of Cataract and Refractive Surgery. 2001;27(2):337–338.
23. Jehan F.S., Mamalis N., Crandall A.S. Spontaneous late dislocation of intraocular lens within the capsular bag in pseudoexfoliation patients. Ophthalmology. 2001;108(10):1727–1731. DOI: 10.1016/s0161-6420(01)00710-2
24. Cionni R.J. Surgical management of the congenitally subluxated crystalline lens using the modified capsular tension ring. Cataract Surgery Technique, Complications, and Management. 2004;305–313.
25. Ritch R. Exfoliation syndrome. Curr. Opin. Ophthalmol. 2001;12(2):124–130. DOI: 10.1097/00055735-200104000-00008
26. Schlotzer-Schrhardt U., Naumann G.O. A histopathologic study of zonular instability in pseudoexfoliation syndrome. Am. J. Ophthalmol. 2004;118:730–743. DOI: 10.1016/s0002-9394(14)72552-8
27. Schlotzer-Schrehardt U. New pathogenetic insights into pseudoexfoliation syndrome/glaucoma. Therapeutically relevant? Ophthalmologe. 2012;109(10):944–951. DOI: 10.1007/s00347-012-2531-1
28. Xu S.L., Gao Z.Z., Wang Y., Chen J. Expression of matrix metalloproteinases and inhibitors on the scleral tissue of lamina cribrosa in rat with experimental chronic ocular hypertension. Zhonghua Yan Ke Za Zhi. 2009;45(3):260–265.
29. Naumann G.O.H., Schlotzer-Schrehardt U., Kuchle M. Pseudoexfoliation syndrome for the comprehensive ophthalmologist: intraocular and systemic manifestations. Ophthalmology. 1998;105(6):951–968. DOI: 10.1016/S0161-6420(98)96020-1
30. Perez-Ardoy A.L., Fernandez-Buenaga R., Alio J.L. Late in-the-bag intraocular lens dislocation requiring explantation: risk factors and outcomes. Eye. 2013;27(7):795– 802. DOI: 10.1038/eye.2013.95
31. Schlotzer-Schrehardt U., Naumann G.O.H. Ocular and systemic pseudoexfoliation syndrome. American Journal of Ophthalmology. 2006;141(5):921–937. DOI: 10.1016/j.ajo.2006.01.047
32. Ostern A.E., Sandvik G.F., Drolsum L. Late in-thebag intraocular lens dislocation in eyes with pseudoexfoliation syndrome. Acta Ophthalmologica. 2014;92(2):184–191. DOI: 10.1111/aos.12024
33. Kanski J.J. Clinical Ophthalmology. A Systematic Approach. 6th edition. Madrid, Spain: Elsevier; 2009.
34. Cheng H.M., Singh O.S., Kwong K.K., Xiong J., Woods B.T., Brady T.J. Shape of the myopic eye as seen with high resolution magnetic resonance imaging. Optometry and Vision Science.1992;69(9):698–701.
35. Wilbrandt H.R., Wilbrandt T.H. Pathogenesis and management of the lens-iris diaphragm retropulsion syndrome during phacoemulsification. Journal of Cataract and Refractive Surgery. 1994;20(1):48–53.
36. Kato S., Suzuki T., Hayashi Y. Risk factors for contraction of the anterior capsule opening after cataract surgery. Journal of Cataract and Refractive Surgery. 2002;28(1):109–112. DOI: 10.1016/s0886-3350(01)00901-4
37. Auffarth G.U., Tsao K., Wesendahl T.A., Sugita A., Apple D.J. Centration and fixation of posterior chamber intraocular lenses in eyes with pseudoexfoliation syndrome: an analysis of explanted autopsy eyes. Acta Ophthalmologica Scandinavica. 1996;74(5):463–467.
38. Hansen S.O., Crandall A.S., Olson R.J. Progressive constriction of the anterior capsular opening following intact capsulorhexis. Journal of Cataract and Refractive Surgery.1993;19(1):77–82.
39. Masket S. Consultation section. Cataract surgical problem. Journal of Cataract & Refractive Surgery. 2002;28(4):577–588.
40. Bayraktar S., Altan T., Kucuksumer T., Yilmaz O. Capsular tension ring implantation after capsulorhexis in phacoemulsification of cataracts associated with pseudoexfoliation syndrome; intraoperative complications and early postoperative findings. Journal of Cataract and Refractive Surgery. 2001;27(10):1620–1628. DOI: 10.1016/s0886-3350(01)00965-8
41. Moreno-Montanes, H. Sanchez-Tocino, R. Rodriguez-Conde, Complete anterior capsule contraction after phacoemulsification with acrylic intraocular lens and endocapsular ring implantation. Journal of Cataract and Refractive Surgery. 2002;28(4):717–719. DOI: 10.1016/s08863350(01)01231-7
42. Gimbel H.V., Sun R. Role of capsular tension rings in preventing capsule contraction. Journal of Cataract & Refractive Surgery. 2000;26(6):791–792. DOI: 10.1016/s0886-3350(00)00505-8
43. Lee D. H., Lee H.-Y., Lee K. H. Effect of a capsular tension ring on the shape of the capsular bag and opening and the intraocular lens. Journal of Cataract and Refractive Surgery. 2001;27(3):452–456. DOI: 10.1016/s08863350(00)00610-6
Review
For citations:
Potemkin V.V., Astakhov S.Yu., Goltsman E.V., Van S.Yu. Assessment of Risk Factors for the Development of Late Intraocular Lens Dislocation. Ophthalmology in Russia. 2021;18(1):103-109. (In Russ.) https://doi.org/10.18008/1816-5095-2021-1-103-109