Intrastromal Strengthening of the Cornea by Technology BLOK in Case of Ectasia after LASIK with Limited Thickness and Inefficiency of Cross-Linking (Clinical Observation)
https://doi.org/10.18008/1816-5095-2021-3S-746-752
Abstract
Iatrogenic keratectasia is a corneal disease caused by refractive surgery, most frequently after laser in situ keratomileusis (LASIK) as a surgical correction of ametropia, and also after injuries, penetrating and lamellar keratoplasty. The following changes are noted in case of keratectasia after laser keratomileusis: an increase in keratometric indices in the central and lower parts of the cornea, a decrease in stromal thickness and a myopic shift in refraction, a progressive impairment of visual functions — a decrease in uncorrected visual acuity, monocular diplopia and an inability of spherocylindrical correction. A thin corneal bed or small residual stromal thickness, re-surgery LASIK in anamnesis, and also the initial preoperative features of the corneal topogram (Irregularity, asymmetric bow tie pattern) are considered to be the main risk factors of keratectasia after LASIK surgery.
Methods. A patient with secondary keratectasia who had previously undergone LASIK and crosslinking was found to have progressive secondary keratectasia and decreased visual functions. An individual allograft was implanted (the form of a Landolt ring, 300 µm, at a depth of 290 µm) using the technology of bandage keratoplasty. Cutting transportat graft and tunnels for implantation were produced with the help of femtosecond laser. The data of visometry and keratotopography were evaluated.
Results. As a result of the formation of the bandage, the functions of the eyes improved, and ectasia did not progress for 6 months. Visual acuity increased from 0.15 to 0.66, the average value of keratometry was 40.35 diopters, with the initial 44.8 diopters. The minimal corneal thickness remained at 440 µm.
Conclusion. The proposed surgical technology BLOK allows to get an effective result in case of keratectasia after LASIK, which is manifested in improving visual functions, strengthening the cornea and normalizing its surface, as well as provides reduction of the further progression of keratectasia.
About the Authors
G. A. OsipyanRussian Federation
Osipyan Grigoriy A., PhD, senior researcher at Corneal Pathology Department, Ophthalmic surgeon at Center Vision Recovery
Rossolimo str., 11A, B, Moscow, 119021;
Lobachevskogo str., 108, Moscow, 119361
V. M. Sheludchenko
Russian Federation
Sheludchenko Vyacheslav M., MD, Professor, head of the Ophthalmic Rehabilitation Department
Rossolimo str., 11A, B, Moscow, 119021
Yusef Naim Yusef
Russian Federation
Yusef Naim Yusef, MD, Professor, director, medical director at Center Vision Recovery
Rossolimo str., 11A, B, Moscow, 119021;
Lobachevskogo str., 108, Moscow, 119361
Kh. Khraystin
Russian Federation
Khraystin Khusam, laboratory assistant, Department of Modern Treatment Methods in Ophthalmology ophthalmologist at Center Vision Recovery
Rossolimo str., 11A, B, Moscow, 119021;
Lobachevskogo str., 108, Moscow, 119361
R. A. Dzhalili
Russian Federation
Dzhalili Rubaba Ali kyzy, postgraduate
Rossolimo str., 11A, B, Moscow, 119021
E. I. Krasnolutskaya
Russian Federation
Krasnolutskaya Elizaveta I., postgraduate
Rossolimo str., 11A, B, Moscow, 119021
S. V. Ermakova
Russian Federation
Ermakova Sofya V., resident
Rossolimo str., 11A, B, Moscow, 119021
References
1. Binder P.S, Lindstrom R.L, Stulting R.D, Donnenfeld E., Wu H., McDonnell P., Rabinowitz Y. Keratoconus and corneal ectasia after LASIK. Comment in Ectasia following laser in situ keratomileusis. J Cataract Refract Surg. 2005;31(11):2035– 2038. DOI: 10.1016/j.jcrs.2005.12.002
2. Randleman J.B. Post-laser in-situ keratomileusis ectasia: current understanding and future directions. Curr Opin Ophthalmol. 2006;17(4):406–412. DOI: 10.1097/01.icu.0000233963.26628.f0
3. Seiler T., Quurke A.W. Iatrogenic keratectasia after LASIK in a case of forme fruste keratoconus. J.Cataract Refract. Surg. 1998;24(7):1007–1009. DOI: 10.1016/s08863350(98)80057-6
4. Speicher L., Göttinger W. Progressive corneal ectasia after laser in situ keratomileusis (LASIK). Klin.Monatsbl. Augenheilkd. 1998;213(4):247–251.
5. Klein S.R, Epstein R.J, Randleman J.B., Stulting R.D. Corneal ectasia after laser in situ keratomileusis in patients without apparent preoperative risk factors. Cornea. 2006;25(4):388–403. DOI: 10.1097/01.ico.0000222479.68242.77J
6. Bohac M., Koncarevic M., Pasalic A., Biscevic A., Merlak M., Gabric N., Patel S. Incidence and Clinical Characteristics of Post LASIK Ectasia: A Review of over 30,000 LASIK Cases. Semin Ophthalmol. 2018;33(7–8):869–877. DOI: 10.1080/08820538.2018.1539183
7. Sheludchenko V.M., Osipyan G.A., Yusef N.Yu., Khraystin Kh., Alharki L., Dzhalili R.A. Bandage lamellar-optical keratoplasty for post-excimer laser keratectasia. Annals of Ophthalmology = Vestnik oftal’mologii. 2019;135(5):171–176 (In Russ.). DOI: 10.17116/oftalma2019135052171
8. Mamikonyan V.R., Osipyan G.A., Khraystin Kh. Bandage therapeutic-optical keratoplasty in treatment of progressing pellucid marginal corneal degeneration (a preliminary report). Annals of Ophthalmology = Vestnik oftal’mologii. 2018;134(5):174–177 (In Russ.). DOI: 10.17116/oftalma2018134051174
9. Mamikonyan V.R., Osipyan G.A., Khraystin Kh., Karamyan A.A., Rozinova V.N. Bandage therapeutic-optical keratoplasty in case of pellucid marginal corneal degeneration. East-West. Point of View = Tochka zrenija. Vostok — Zapad. 2018;(1):18–21 (In Russ.). DOI: 10.25276/2410-1257-2018-1-18-21
10. Osipyan G.A., Khraystin K. Possibilities of Intralamellar Keratoplasty in Rehabilitation of Keratoconus Patients. Ophthalmology in Russia = Oftal’mologiya. 2019;16(2):169–173 (In Russ.). DOI: 10.18008/1816-5095-2019-2-169-173
11. Colin J. Intacs inserts for treating keratoconus: one-year results. Ophthalmology. 2011;108(8):1409–1414. DOI: 10.1016/S0161-6420(01)00646-7
12. Alio J.L. One or 2 intacs segments for the correction of keratoconus. J Cataract. Refract. Surg. 2005;31(5):943–953. DOI: 10.1016/j.jcrs.2004.09.050
13. Hashemi H., Alvani A., Seyedian M.A., Yaseri M., Khabazkhoob M., Esfandiari H. Appropriate Sequence of Combined Intracorneal Ring Implantation and Corneal Collagen Cross-Linking in Keratoconus: A Systematic Review and Meta-Analysis. Cornea. 2018 Dec;37(12):1601–1607. DOI: 10.1097/ICO.0000000000001740
14. Hafezi F., Kanellopoulos J., Wiltfang R., Seiler T. Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis. J. Cataract Refract. Surg. 2007;33(12): 2035–2040. DOI: 10.1016/j.jcrs.2007.07.028
15. Jacob S., Patel S.R. Corneal allogenic intrastromal ring segments (CAIRS), combined with corneal cross-linking for keratoconus. J Refract Surg. 2018 May 1;34(5):296–303. DOI: 10.3928/1081597x-20180223-01
Review
For citations:
Osipyan G.A., Sheludchenko V.M., Yusef Yu., Khraystin Kh., Dzhalili R.A., Krasnolutskaya E.I., Ermakova S.V. Intrastromal Strengthening of the Cornea by Technology BLOK in Case of Ectasia after LASIK with Limited Thickness and Inefficiency of Cross-Linking (Clinical Observation). Ophthalmology in Russia. 2021;18(3S):746-752. (In Russ.) https://doi.org/10.18008/1816-5095-2021-3S-746-752