Terms of Use of Perfluoroorganic Compounds for Intraocular Tamponade after Vitrectomy for Rhegmatogenous Retinal Detachment
https://doi.org/10.18008/1816-5095-2024-1-58-65
Abstract
Perfluoroorganic compounds are surgically invasive medical devices, which are represent liquid fluorine-containing substances, chemically and biologically inert and thermodynamically stable due to the strength of chemical bonds between carbon and fluorine atoms. Due to their density, these compounds are able to exert pressure on the detached retina and expel the subretinal fluid. Currently, the use of perfluoroorganic compounds is limited to intraoperative use due to multiplesevere complications of prolonged tamponade. In the analyzed studies, the use of perfluoroorganic compounds as a tamponade was divided into short-term and medium-term tamponade of the vitreal cavity. The authors preferred such tactic for restoring the anatomical fit and a higher rate of aging of retinal laser coagulates, despite proven postoperative complications. Based on the analysis of the results of the presented studies, it can be concluded that it is possible to safely use perfluoroorganic compounds for short-term tamponade of the vitreal cavity. However, among the analyzed domestic and foreign studies, no large-scale statistically significant studies were found to justify the choice of tamponade for retinal breaks different localization, terms of retinal detachment and stage of proliferative vitreoretinopathy. All of that determines the relevance of a more detailed study of the use of perfluoroorganic compounds for short-term tamponade of the vitreal cavity.
About the Authors
R. R. Fayzrakhmanov
N.I. Pirogov National Medical Surgical Center;
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center
Russian Federation
Russian Federation
Fayzrakhmanov Rinat R. — MD, professor of the Eye Diseases Department, head of the Eye Diseases Department, Institute of Advanced Training of Physicians, head of Center of Ophthalmology
Nizhnyaya Pervomayskaya str., 70, Moscow, 105203,
Nizhnyaya Pervomayskaya str., 65, Moscow, 105203
M. M. Shishkin
N.I. Pirogov National Medical Surgical Center;
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center
Russian Federation
Russian Federation
Shishkin Michail M. — MD, professor, professor of the Eye Diseases Institute Department of Advanced Training of Physicians, the main ophthalmologist of Center of Ophthalmology
Nizhnyaya Pervomayskaya str., 70, Moscow, 105203,
Nizhnyaya Pervomayskaya str., 65, Moscow, 105203
E. A. Larina
N.I. Pirogov National Medical Surgical Center;
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center
Russian Federation
Russian Federation
Larina Evgenia A. — PhD, assistant of the Eye Diseases Institute Department of Advanced Training of Physicians, ophthalmologist of Center of Ophthalmology
Nizhnyaya Pervomayskaya str., 70, Moscow, 105203,
Nizhnyaya Pervomayskaya str., 65, Moscow, 105203
E. E. Vaganova
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center
Russian Federation
Russian Federation
Vaganova Elena E. — postgraduate of department of Eye Diseases Institute of Advanced Training of Physicians
Nizhnyaya Pervomayskaya str., 65, Moscow, 105203
O. L. Sekhina
Institute of Advanced Training of Physicians of N.I. Pirogov National Medical Surgical Center
Russian Federation
Russian Federation
Sekhina Olga L. — Postgraduate of department of Eye Diseases of Institute of Advanced Training of Physicians
Nizhnyaya Pervomayskaya str., 65, Moscow, 105203
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Review
For citations:
Fayzrakhmanov R.R., Shishkin M.M., Larina E.A., Vaganova E.E., Sekhina O.L. Terms of Use of Perfluoroorganic Compounds for Intraocular Tamponade after Vitrectomy for Rhegmatogenous Retinal Detachment. Ophthalmology in Russia. 2024;21(1):58-65. (In Russ.) https://doi.org/10.18008/1816-5095-2024-1-58-65
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