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A Case of Mucogenic Iris Cyst with Ophthalmohypertension Followed by Iridectomy with Iridoplasty

https://doi.org/10.18008/1816-5095-2025-3-632-637

Abstract

There is a clinical case of mucogenic iris cyst with ocular hypertension. The patient had noticed an iris spot since childhood. At the age of 33, she was diagnosed with iridocorneal syndrome and iris cyst. At the age of 38, an IOP decompensation was the reason for fistulizing surgery. At 41 years, progression of the iris cyst was noted, which was an indication for iridectomy with iridoplasty. According to the histological examination, the cyst wall is presented by sclerotic iris stroma, as well as dense unformed fibrous tissue fused with Descemet's membrane. In the lumen of the cyst, mucous contents are determined with the formation of mucous globules and an admixture of native and hemolyzed erythrocytes, clusters of macrophages with abundant light vacuolated cytoplasm. The inner surface of the cyst is lined with mature multi-row cylindrical intestinal-type epithelium and numerous goblet cells.

About the Authors

S. V. Saakyan
Helmholtz National Medical Research Center of Eye Diseases; A.I. Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation

Svetlana V. Saakyan - corresponding member of RAS, MD, Professor, head of Ocular oncology and radiology department, deputy director of education, chair of ophthalmology.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062; Delegatskaya str., 20/1, Moscow, 127473



N. S. Izmailova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Natalia S. Izmailova - head of the Pathological fnatomy and histology department, leading researcher, pathologist.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062



S. Yu. Petrov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Sergey Yu. Petrov - MD, head of Glaucoma department.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062



R. A. Tatskov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Robert A. Tatskov - PhD, ophthalmologist, Ocular oncology and radiology department.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062



O. G. Panteleeva
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Olga G. Panteleeva - MD, leading researcher, Ocular oncology and radiology department.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062



A. A. Zharov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Andrey A. Zharov - researcher at the Pathological anatomy and histology department, pathologist.

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062



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Review

For citations:


Saakyan S.V., Izmailova N.S., Petrov S.Yu., Tatskov R.A., Panteleeva O.G., Zharov A.A. A Case of Mucogenic Iris Cyst with Ophthalmohypertension Followed by Iridectomy with Iridoplasty. Ophthalmology in Russia. 2025;22(3):632-637. (In Russ.) https://doi.org/10.18008/1816-5095-2025-3-632-637

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ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)