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Experience of Xenoplast Drainage Using in Non-penetrating Surgery of Primary Open-angle Glaucoma

https://doi.org/10.18008/1816-5095-2025-3-612-617

Abstract

Purpose: to evaluate the hypotensive efficacy and safety of Xenoplast drainage in non-penetrating surgery of primary open-angle glaucoma. Materials and methods. The analysis of the medical records of 157 patients (157 eyes) with primary open-angle glaucoma who underwent hypotensive non-penetrating surgery (non-penetrating deep sclerectomy — NDSE) using Xenoplast drainage (group 1) and without drainage (group 2). The results were evaluated for up to 36 months. Results. The positive effect of the operation, including absolute and relative success, was 96% in group 1 on day 6, then gradually decreased and was 74 % after 36 months. In group 2, the positive effect was 100 % and decreased to 58 % at the appropriate time of follow-up. In both groups, in the early postoperative period, there was a low percentage of eye complications (5.4 % and 4.8 %), typical for non-penetrating antiglaucoma surgeries. The number of descemetogoniopunctures, performed as the second stage of NDSE, was insufficient, both in the 1st group — 42 %, and in the 2nd — 51 %. Conclusion. All of the above points to the advantage of using Xenoplast drainage during non-penetrating deep sclerectomy.

About the Authors

T. V. Gavrilova
E.A. Vagner Perm State Medical University; Perm Regional Clinical Hospital
Russian Federation

Tatiana V. Gavrilova - MD, Professor, RAS Corresponding Member, head of the Ophthalmology Department.

Petropavlovskaja str., 26, Perm, 614990; Pushkin str., 85, Perm, 614045



Yu. A. Kozyreva
E.A. Vagner Perm State Medical University
Russian Federation

Yulia A. Kozyreva - resident of the Ophthalmology Department.

Petropavlovskaja str., 26, Perm, 614990



S. N. Mukhamadeeva
Perm Regional Clinical Hospital
Russian Federation

Svetlana N. Mukhamadeeva - head of the 2nd Ophthalmology Department.

Pushkin str., 85, Perm, 614045



L. I. Solovyeva
E.A. Vagner Perm State Medical University
Russian Federation

Larisa I. Solovyeva - PhD, Associate Professor.

Petropavlovskaja str., 26, Perm, 614990



M. V. Chereshneva
Institute of Immunology and Physiology, Russian Academy of Sciences
Russian Federation

Mаrgarita V. Chereshneva - MD, Professor, principal researcher, Honored Scientist of the Russian Federation.

Pervomajskaja str., 91, Ekaterinburg, 620041



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Review

For citations:


Gavrilova T.V., Kozyreva Yu.A., Mukhamadeeva S.N., Solovyeva L.I., Chereshneva M.V. Experience of Xenoplast Drainage Using in Non-penetrating Surgery of Primary Open-angle Glaucoma. Ophthalmology in Russia. 2025;22(3):612-617. (In Russ.) https://doi.org/10.18008/1816-5095-2025-3-612-617

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ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)