Proteomic Analysis of Normal Lacrimal Fluid: Identification of Major and Unique Proteins (Clinical and Experimental Study)

The protein composition of lacrimal fluid changes in various pathological conditions, making it a promising biomarker for the diagnosis of ophthalmic and systemic diseases. Modern methods of lacrimal fluid analysis include chromatography and mass spectrometry, which ensure highly accurate identification and quantification of proteins, serving as indispensable tools for proteome studies. The aim of this study was to investigate the protein composition of lacrimal fluid using mass spectrometry in 5 healthy volunteers, identify the main components and unique proteins, and analyze their significance for the diagnosis and treatment of ophthalmic diseases.

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