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Morphofunctional Peculiarities of Platelet Rich Plasma and Its Application in Ophthalmology

https://doi.org/10.18008/1816-5095-2018-4-388-393

Abstract

This article is dedicated to the realistic, present-day problem in treating patients with a damaged cornea. It contains a general summary of the practical experience of treatments in various spheres of medicine and in ophthalmology in particular, concerning the new developing method of restoring tissue with the aid of platelet rich plasma. This is a branch of regenerative medicine. In ophthalmology an effective method has long been sought for treating patients with a damaged cornea. It is well-known that platelet rich plasma contains a high quantity of elements which contribute to growth: thrombocyte, transformation, insulin-like, epidermal etc. And although the mechanism of the parts their role has not been sufficiently studied, the positive results of the PRP use in various fields of surgical medicine and in particular in the treatment of burns and ulcers of the tissue, speak of the key role being played in the growth factor and the process of tissue restoration. Despite the fact that this method has not been fully studied by ophthalmologists, it is of great interest to practising doctors, considering its potential value due to it being therapeutically effective and both simple and economic to produce. Our aim here is to give a short overview of the literature which contains descriptions of the morphological qualities of thrombocytes, to note and describe the characteristics of PRP and its role in the regeneration of tissue, to make special note of the history of the discovery of the growth factor in medico-biological science and to analyze the publications which give details of the PRP use.

About the Authors

E. V. Fedoseeva
Moscow Helmholtz’s Research Institute of Eye Diseases
Russian Federation

ophtalmologist

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062, Russia



E. V. Chentsova
Moscow Helmholtz’s Research Institute of Eye Diseases
Russian Federation

MD, professor

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062, Russia



N. V. Borovkova
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation

MD

Bolshaya Sukharevskaya sq., 3, bldng 21, Moscow, 129090, Russia



I. B. Alekseeva
Moscow Helmholtz’s Research Institute of Eye Diseases
Russian Federation

PhD, ophthalmologist

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062, Russia



I. Yu. Romanova
Moscow Helmholtz’s Research Institute of Eye Diseases
Russian Federation

PhD, ophthalmologist

Sadovaya-Chernogryazskaya str., 14/19, Moscow, 105062, Russia



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Review

For citations:


Fedoseeva E.V., Chentsova E.V., Borovkova N.V., Alekseeva I.B., Romanova I.Yu. Morphofunctional Peculiarities of Platelet Rich Plasma and Its Application in Ophthalmology. Ophthalmology in Russia. 2018;15(4):388-393. (In Russ.) https://doi.org/10.18008/1816-5095-2018-4-388-393

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ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)