Comprehensive Approach to the Management of Patients with Recurrent Corneal Erosions
https://doi.org/10.18008/1816-5095-2021-2-338-345
Abstract
In the Russian literature, there are only a few works that summarize their own experience in the treatment of recurrent corneal erosion (RCE) in a limited group of patients, which actualizes further research in this direction.
Objective: to develop and evaluate the clinical effectiveness of an integrated approach to the management of patients with RCE.
Patients and methods. 69 patients (69 eyes) with RCE and a disease duration of at least two years, who were divided into 3 groups according to the frequency of relapses: group 1 (12 people) — episodes of RCE no more than 2–4 times a year; Group 2 (19 people) — RCE episodes no more than once a month; Group 3 (38 people) — RCE episodes more than 2 times a month. All patients were cured by pharmacological support, if conservative therapy was ineffective (1 relapse during treatment within 1 month), phototherapeutic keratectomy (PTK) was performed with the application of a bandage contact lens and the appointment of pathogenetically-oriented treatment for up to 1 year. The average follow-up period was 28.6 ± 6.1 months.
Results and discussion. In group 1, during the entire period of observation, RCE was compensated by the therapy, in the other groups, the effectiveness was lower, which in 41 (59.4 %) cases required the implementation of PTK. There were no relapses of corneal erosion after PTK with subsequent pathogenetically-oriented therapy, including heparin-containing medications in instillation (CHYLOPARIN-KOMOD®) and ointment forms (PARIN-POS®) for 1 year.
Conclusion. The high effectiveness of PTK with subsequent pathogenetically-oriented pharmacological support may be the basis for a broader recommendation of this method in patients with RCE and a relapse rate of more than 1 time a month.
About the Authors
A. V. Doga
The S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation
Russian Federation
MD, PhD, Professor, deputy general director for research and clinical work,
Beskudnikovsky blvd, 59A, Moscow, 127486
N. V. Maychuk
The S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation
Russian Federation
PhD, senior researcher of Department of laser refractive surgery,
Beskudnikovsky blvd, 59A, Moscow, 127486
I. A. Mushkova
The S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation
Russian Federation
MD, PhD, head of Department of laser refractive surgery,
Beskudnikovsky blvd, 59A, Moscow, 127486
I. A. Babitskaya
The S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation
Russian Federation
ophthalmologist,
Beskudnikovsky blvd, 59A, Moscow, 127486
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Review
For citations:
Doga A.V., Maychuk N.V., Mushkova I.A., Babitskaya I.A. Comprehensive Approach to the Management of Patients with Recurrent Corneal Erosions. Ophthalmology in Russia. 2021;18(2):338-345. (In Russ.) https://doi.org/10.18008/1816-5095-2021-2-338-345
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