Обзор топических форм антимикробных препаратов, применяемых в офтальмологии
Аннотация
Обзор представляет сведения о различных группах антимикробных препаратов — фторхинолонов, аминогликозидов, макролидов, фузидовой кислоты, хлорамфеникола — их эффективности в отношении разнообразных микроорганизмов. Проанализированы данные, полученные различными исследователями. Особенное внимание уделено вопросу антибиотикорезистентности возбудителей инфекций в офтальмологии, подробно описана фармакокинетика топических антимикробных препаратов, применяемых в офтальмологии, их безопасность, переносимость. Представлены одобренные в РФ показания к применению топических АМП в офтальмологии. Сделан вывод о том, что с учетом фармакокинетических и фармакодинамических характеристик, благоприятного профиля безопасности и хорошей переносимости, следует признать, что именно фторхинолоны являются препаратами выбора для эмпирической антимикробной терапии инфекций в офтальмологии.
Об авторе
Е. В. Довгань
АНО Институт клинической фармакологии
ОГБУЗ Смоленская областная клиническая больница
Россия
Россия
отделение клинической фармакокинетики
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Для цитирования:
Довгань Е.В. Обзор топических форм антимикробных препаратов, применяемых в офтальмологии. Офтальмология. 2014;11(2):10-18. https://doi.org/10.18008/1816-5095-2014-2-10-18
For citation:
Dovgan’ E.V. Topical antimicrobial agents in ophthalmology. A review. Ophthalmology in Russia. 2014;11(2):10-18. (In Russ.) https://doi.org/10.18008/1816-5095-2014-2-10-18
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