Preview

Ophthalmology in Russia

Advanced search

Analysis of the Significance of Keratotopography, Keratopachymetry and Optical Coherence Tomography of the Cornea in the Differential Diagnosis of Pellucid Marginal Corneal Degeneration and Keratoconus

https://doi.org/10.18008/1816-5095-2022-3-565-570

Abstract

Purpose. To analyze the significance of keratotopography, keratopachymetry and optical coherence tomography of the cornea in the differential diagnosis of pellucid marginal corneal degeneration with keratoconus.

Patients and methods. A retrospective analysis of data from outpatient medical records of 62 patients (62 eyes) with keratectasias and the presence of a crab claw keratotopogram was carried out. Optical coherence tomography of the cornea was performed in all eyes and the parameters of keratopachymetry and corneal elevation were studied on the Pentacam.

Results. Optical coherence tomography allowed in all cases to determine the localization of the corneal thinning zone. Only 5 out of 13 indicators of keratopachymetry had statistically significant intergroup differences and can be used in the differential diagnosis of keratectasias.

Conclusion. The analysis showed that, in contrast to keratotopography, keratopachymetry and optical coherence tomography of the cornea make it possible to differentiate the type of primary keratectasia. 

About the Authors

I. V. Vasilieva
Khabarovsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation

ophthalmologist of Refractive surgery department,

Tikhookeanskaya str., 211, Khabarovsk, 680033



S. V. Kostenev
S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation

MD, senior researcher of Laser refractive surgery department,

Beskudnikovsky blvd, 59A, Moscow, 127486



A. V. Vasiliev
Khabarovsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution
Russian Federation

PhD, chief of Cataract surgery department, ophthalmologist,

Tikhookeanskaya str., 211, Khabarovsk, 680033



References

1. Bikbov M.M., Bikbova G.M. Corneal ectasia (pathogenesis, pathomorphology, clinical picture, diagnosis, treatment). Moscow: Oftal’mologiya, 2011. 164 p. (In Russ.).

2. Krachmer D., Peley D. Cornea. Atlas / ed. N.I. Kuryshevа. Moscow: Logosfera; 2007. 370 p. (In Russ.).

3. Slonimskiy A.Yu., Slonimskiy Yu.B., Sitnik H.V., Myagkov A.V., Milash S.V. Pellucid marginal corneal degeneration and keratoconus: differential diagnosis and management of patients. Оphthalmology in Russia = Oftal’mologiya. 2019;16(4):433–442 (In Russ.). DOI: 10.18008/1816-5095-2019-4433-441

4. Myagkov A.V., Abugova T.D. Diagnosis of rare corneal diseases in the conditions of the optical salon: keratotorus. Frames and lenses = Opravy i linzy. 2012;2(68):36– 38 (In Russ.).

5. Rapuano K.Dzh., Kheng V. Rogovitsa. Cornea. Ophthalmology Atlas. ed. A.A. Kasparov. Moscow: Geotar-Media, 2010. 320 p. (In Russ.).

6. Mohr N., Shajari M., Krause D., Kassumeh S., Siedlecki J., Priglinger S.G. Mayer W.J., Luft N. Pellucid marginal degeneration versus keratoconus: distinction with wide-field SD-OCT corneal sublayer pachymetry. British Journal of Ophthalmology Published Online First. 2020. [Процитировано 22 апреля 2021]. Доступно: https://bjo.bmj.com/content/early/2020/10/13/bjophthalmol-2020-316496 DOI: 10.1136/bjophthalmol-2020-316496

7. Shimazaki J., Maeda N., Hieda O., Ohashi Y., Murakami A., Nishida K., Tsubota K. National survey of pellucid marginal corneal degeneration in Japan. Jpn J Ophthalmol. 2016;60(5):341–348. DOI: 10.1007/s10384-016-0462-0

8. Martínez-Abad A., Piñero D.P. Pellucid marginal degeneration: Detection, discrimination from other corneal ectatic disorders and progression. Cont Lens Anterior Eye. 2019;42(4):341–349. DOI: 10.1016/j.clae.2018.11.010

9. Sridhar M.S., Mahesh S., Bansal A.K., Nutheti R., Rao G.N. Pellucid marginal corneal degeneration. Ophthalmology. 2004;111(6):1102–1107. DOI: 10.1016/j.ophtha.2003.09.035

10. Lee B.W., Jurkunas U.V., Harissi-Dagher M., Poothullil A.M., Tobaigy F.M., Azar D.T. Ectatic disorders associated with a claw-shaped pattern on corneal topography. Am J Ophthalmol. 2007;144(1):154–156. DOI: 10.1016/j.ajo.2007.02.032

11. Belin M.W., Ambrosio R. Scheimpflug imaging for keratoconus and ectatic disease. Indian J Ophthalmol. 2013;61(8):401–406. DOI: 10.4103/0301-4738.116059

12. Fuchihata M., Maeda N., Toda R., Koh S., Fujikado T., Nishida K. Characteristics of corneal topographic and pachymetric patterns in patients with pellucid marginal corneal degeneration. Jpn J Ophthalmol. 2014;58(2):131–138. DOI: 10.1007/s10384-013-0291-3

13. Koc M., Tekin K., Kosekahya M Inanc P., Yilmazbas P. Crab claw pattern on corneal topography: pellucid marginal degeneration or inferior keratoconus? Eye (Lond). 2018;32(1):11–18. DOI: 10.1038/eye.2017.198

14. Koçluk Y., Yalniz-Akkaya Z., Burcu A., Örnek F. Comparison of Scheimpflug imaging analysis of pellucid marginal corneal degeneration and keratoconus. Ophthalmic Res. 2015;53(1):21–27. DOI: 10.1159/000365518

15. Gomes J.A., Tan D., Rapuano C.J., Belin M.W., Ambrosio R. Jr., Jose L., Malecaze F., Nishida K., Sangwan V.S. Global consensus on keratoconus and ectatic diseases Cornea. 2015;34(4):359–369. DOI: 10.1097/ICO.0000000000000408


Review

For citations:


Vasilieva I.V., Kostenev S.V., Vasiliev A.V. Analysis of the Significance of Keratotopography, Keratopachymetry and Optical Coherence Tomography of the Cornea in the Differential Diagnosis of Pellucid Marginal Corneal Degeneration and Keratoconus. Ophthalmology in Russia. 2022;19(3):565-570. (In Russ.) https://doi.org/10.18008/1816-5095-2022-3-565-570

Views: 721


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)