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Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review

https://doi.org/10.18008/1816-5095-2023-3-398-404

Abstract

Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of that pathology. The causes of age-related macular degeneration are not fully understood, in spite of keeping a great amount of knowledge at etiology, pathogenesis, diagnosis and modern types of treatment. The problem of age-related macular degeneration treatment has remained actual nowadays. Now, the medicine doesn’t have etiotropic treatment of AMD, because we still don’t know a definite etiologic factor of this developing disease. The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. The disadvantage of current treatment methods is a narrow focus at one of the pathogenesis components or using as symptomatic therapy. The analysis of literature date has allowed noticing of using of an extracorporeal hemocorrection as perspective way at exploration of new methods of treatment of dry age-related macular degeneration.

About the Authors

A. N. Kulikov
S.M. Kirov Military Medical Academy
Russian Federation

Kulikov Aleksey N., MD, Professor, head of the Ophthalmology department named after Professor V.V. Volkov

Academician Lebedev str., 6, Saint Petersburg, 194044



M. V. Zakharov
S.M. Kirov Military Medical Academy
Russian Federation

Zakharov Mikhail V., PhD, deputy head of the Nephrology and efferent therapy department

Academician Lebedev str., 6, Saint Petersburg, 194044



A. A. Volozhev
S.M. Kirov Military Medical Academy
Russian Federation

Volozhev Aleksandr A., adjunct of the Ophthalmology department named after Professor V.V. Volkov

Academician Lebedev str., 6, Saint Petersburg, 194044



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Review

For citations:


Kulikov A.N., Zakharov M.V., Volozhev A.A. Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review. Ophthalmology in Russia. 2023;20(3):398-404. (In Russ.) https://doi.org/10.18008/1816-5095-2023-3-398-404

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