Preview

Ophthalmology in Russia

Advanced search

Cataract and progressing keratoconus — solution?

https://doi.org/10.18008/1816-5095-2015-3-36-43

Abstract

Purpose: To develop an uniform method of the treatment for patients with progressive keratoconus (stage 1‑2) and cataract.

Patients and methods: 4 patients (5 eyes) with cataract and progressive keratoconus stage 1‑2 were enrolled in the study. Mean age was 42 years. In all patients, standard ophthalmic examination as well corneal topography, anterior segment optical coherence tomography, biometry, and IOL power calculations using IOLMaster were performed. Mean uncorrected visual acuity (UCVA) was 0.1 while mean best-corrected visual acuity (BCVA) was 0.4. Surgical technique included two steps. The first step was the creation of corneal tunnels with femtosecond laser with subsequent phaco and monofocal aspheric IOL implantation. The second step (1‑2 weeks later) was the implantation of intrastromal ring segments based on corneal topography and corneal crosslinking.

Results: After the first step, all patients had myopic refraction (from –1.0 D to –2.5 D). Cylindrical component was almost unchanged. After the second step, the patients reported the vision improvement, mainly due to UCVA. Both spherical (myopic) and cylindrical components decreased, mainly due to the steep meridian. After the treatment, optical power of the cornea decreased, mainly due to the steep meridian. UCVA was 0.6 or more in 60 % of cases, final BCVA was 0.8‑1.0 in 80 % of cases. Neither intraoperative nor postoperative (follow-up was 2 years) complications were observed.

Conclusions: Combined phaco and prior creation of corneal tunnels with subsequent intrastromal ring segment implantation and crosslinking in patients with cataract and progressive keratoconus stage 1‑2 is safe, provides good predictable outcome and significantly reduces rehabilitation period.

About the Authors

K. B. Pershin
Ophthalmological clinic «Excimer», Apraksin Lane, b. 6, St. Petersburg, 191023, Russia
Russian Federation


E. P. Gurmizov
Ophthalmological clinic «Excimer», Apraksin Lane, b. 6, St. Petersburg, 191023, Russia
Russian Federation


References

1. Krumeich J. H., Daniel J., Knulle A. Live-epikeratophakia for keratoconus. J. Cataract Refract. Surg. 1998; 24: 456‑463.

2. Pearson A. R., Soneji B., Sarvananthan N, Sandford-Smith J. H. Does ethnic origin influence the incidence or severity of keratoconus? Eye. 2000; 14 (4):625‑628.

3. Kennedy R. H,. Bourne W. M., Dyer J. A. A 48‑year clinical and epidemiologic study of keratoconus. Am. J. Ophthalmol. 1986; 101 (3): 267‑273.

4. Bialasiewicz A., Edward D. P. Corneal ectasias: study cohorts and epidemiology. Middle East Afr. J. Ophthalmol. 2013; 20 (1): 3‑4.

5. Binder P. S. Analysis of ectasia after laser in situ keratomileusis: risk factors. J. Cataract Refract. Surg. 2007; 33 (9): 1530‑1538.

6. Chen M. C., Lee N., Bourla N., Hamilton D. R. Corneal biomechanical measurements before and after laser in situ keratomileusis. J. Cataract Refract. Surg. 2008; 34 (11): 1886‑1891.

7. Kirwan C., O’Malley D., O’Keefe M. Corneal hysteresis and corneal resistance factor in eratoectasia: findings using the Reichert ocular response analyzer. Ophthalmologica. 2008; 222 (5): 334337.

8. Randleman J. B., Woodward M., Lynn M. J., Stulting R. D. Risk assessment for ectasia after corneal refractive surgery. Ophthalmology. 2008; 115 (1): 37‑50.

9. Georgiou T., Funnell C. L., Cassels-Brown A., O’Conor R. Influence of ethnic origin on the incidence of keratoconus and associated atopic disease in Asians and white patients. Eye. 2004; 18 (4): 379‑383.

10. Knapp A. Etiology and treatment of keratoconus. Trans. Am. Ophtalmol. 1929; 27: 63‑72.

11. Bron A. J. Keratoconus. Cornea. 1988; 7: 163‑169.

12. Petrosyants E. A. [Early diagnosis of keratoconus]. O ranney diagnostike keratokonusa. [Ophthalmological Journal]. Oftal’mologicheskiy zhurnal. 1962; 6: 362‑365. (in Russ.).

13. Puchkovskaya N. A., Titarenko Z. D. [Keratoconus]. Keratokonus. Kishinev, Timpul, 1990. (in Russ.).

14. Leung K. K. RGP fitting philosophies for keratoconus. Clin. Exp. Optometry. 1999; 82 (6): 230‑235.

15. Ferrara de A., Cunha P. Tecnica cirurgica para correçao de miopia; Anel corneano intra-estromal. Rev. Bras. Oftalmol. 1995; 54: 577‑588.

16. Piñero D. P., Alio J. L., El Kady B., Coskunseven E., Morbelli H., Uceda- Montanes A., Maldonado M. J., Cuevas D., Pascual I. Refractive and aberrometric outcomes of intracorneal ring segments for keratoconus: Mechanical versus femtosecond-assisted procedures. Ophthalmology. 2009; 116: 1675‑1687.

17. Alio J. L., Vega-Estrada A., Esperanza S., Barraquer R. I., Teus M. A., Murta J. ntrastromal corneal ring segments: how successful is the surgical treatment of keratoconus? J. Ophthalmol. 2014; 21 (1): 3‑9.

18. Dvali M. L., Tsintsadze N. A., Sirbiladze Ba. Corneal intrastromal ring implantation in keratoconus. Highlights Ophthalmol. 2007; 35 (1): 11‑13.

19. Moroz Z. I., Izmaylova S. B., Kalinnikov Yu. Yu., R. Gurbanov, Legkikh S. L., Shormaz I. N. [Surgical treatment of early keratoconus using intrastromal keratoplasty with segment implantation]. Khirurgicheskoe lechenie keratokonusa na rannikh stadiyakh zabolevaniya metodom intrastromal’noy keratoplastiki s implantatsiey segmentov. [Ophthalmosurgery]. Oftal’mokhirurgiya. 2012; 4: 22‑27. (in Russ.).

20. Spoerl E., Huhle M., Seiler T. Induction of cross-links in corneal tissue. Exp. Eye Res. 1998; 66 (1): 97‑103.

21. Wollensak G., Spoerl E., Seiler T. Riboflavin / ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am. J. Ophthalmol. 2003; 135 (5): 620‑627.

22. Seung J. L., Hyun S. K., Il H. K. Sequential intrastromal corneal ring implantation and cataract surgery in a severe keratoconus patient with cataract. Korean J. Ophthalmol. 2012; 26 (3): 226‑229.

23. Sauder G., Jonas J. B. Treatment of keratoconus by toric foldable intraocular lenses. Eur. J. Ophthalmol. 2003; 13: 577‑579.

24. Navas A., Suárez R. One-year follow-up of toric intraocular lens implantation in forme fruste keratoconus. J. Cataract Refract. Surg. 2009; 35: 2024‑2027.

25. Visser N., Gast S. T., Bauer N. J., Nuijts R. M. Cataract surgery with toric intraocular lens implantation in keratoconus: a case report. Cornea. 2011; 30: 720‑723.

26. Parikakis E. A., Chatziralli I. P., Peponis V. G., David G., Chalkiadakis S., Mitropoulos P. G. Toric intraocular lens implantation for correction of astigmatism in cataract patients with corneal ectasia. Case Rep. Ophthalmol. 2013; 4: 219‑228.


Review

For citations:


Pershin K.B., Gurmizov E.P. Cataract and progressing keratoconus — solution? Ophthalmology in Russia. 2015;12(3):36-43. (In Russ.) https://doi.org/10.18008/1816-5095-2015-3-36-43

Views: 2352


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)