Corneal Crosslinking in Keratoconus in Children, Evaluation of Efficiency in the Remote Period. Clinical Case with 5-year Follow-up
https://doi.org/10.18008/1816-5095-2025-3-646-653
Abstract
Keratoconus in children has been diagnosed relatively recently, which is explained by the difficulties of examination (low compliance, concomitant diseases). The peculiarity of keratoconus in children is that it can develop unnoticed, often remaining unrecognized until adolescence, which creates additional difficulties in early diagnosis and treatment. The corneal collagen crosslinking (CXL) method, as a minimally invasive method, is a priority in the treatment of pediatric patients. Despite the confirmed effectiveness in short-term studies, long-term results remain a key aspect for assessing the sustainability of the therapeutic effect. This article presents a clinical case of a patient with keratoconus, observed for 5 years after crosslinking. Objective: To assess the condition of the cornea and ocular surface in a pediatric patient diagnosed with: OU High myopia, myopic astigmatism. OD Keratoconus stages 2-3 operated (corneal crosslinking was performed in 2020), OS Keratoconus stages 1-2. Results: Patient N., 17 years old, was observed with a diagnosis of keratoconus stages 2-3 in the right eye. Crosslinking was performed 5 years ago, currently showing stable remission. A standard and specialized ophthalmological examination was performed. Conclusion: Corneal cross-linking is an effective technique that allows for the stabilization of progressive keratoconus in children (5-year follow-up). The effectiveness of the method has been confirmed using modern high-tech methods, such as corneotopography and the Ocular Response Analyzer (ORA).
About the Authors
E. Yu. MarkovaRussian Federation
Elena Yu. Markova - MD, Professor of the Eye Diseases Department, ophthalmologist of the highest category.
Dolgorukovskaya str., 4, Moscow, 127006; Polina Osipenko str., 10, bldg. 1, Moscow, 123007
N. A. Gavrilova
Russian Federation
Natalya A. Gavrilova - MD, Professor, head of the Department of Eye Diseases.
Dolgorukovskaya str., 4, Moscow, 127006
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Review
For citations:
Markova E.Yu., Gavrilova N.A. Corneal Crosslinking in Keratoconus in Children, Evaluation of Efficiency in the Remote Period. Clinical Case with 5-year Follow-up. Ophthalmology in Russia. 2025;22(3):646-653. (In Russ.) https://doi.org/10.18008/1816-5095-2025-3-646-653