Features of ophthalmoneuroprotection in patients with open-angle glaucoma in combination with diabetic retinopathy
https://doi.org/10.18008/1816-5095-2014-1-66-72
Abstract
Aim: of this study is to evaluate ophthalmoneuroprotectional treatment of patients with POAG and diabetes mellitus type II in a specialized hospital.
Material and methods: We have performed retro — and prospective analysis of the combined treatment of 130 patients (248 eyes) with a combination of primary open-angle glaucoma and diabetic retinopathy. Evaluation of the effectiveness of treatment was conducted on the following criteria: the severity of the hypotensive effect, the degree
of improvement and duration of remission of major ophthalmic indicators. The patients were divided into four clinical — homogeneous groups: primary — 40 people (77 eyes), the comparison group I — 37 persons (71 eyes), the comparison group II — 33 people (60 eyes), the control group — 20 people (40 eyes).
Results: Combination of different treatment strategy of laser and conservative treatment was tested. The result has been designed for optimal balance improving performance and reducing ocular side effects. Retinalamin ® 5 mg parabulbare number 10, Tanakan 1 tablet 3 times a day — 3 months. The optimal timing of re-treatment (at least 1
time in 9 months), in the case of significant progression of glaucomatous optic neuropathy — the timing is solved individually.
About the Authors
O. I. Borzunov
Ural state medical university, Ministry of Health
Russian Federation
ophthalmology department
Russian Federation
ophthalmology department
С. Коротких
Ural state medical university, Ministry of Health
Russian Federation
ophthalmology department
Russian Federation
ophthalmology department
References
1. Egorov E. A. i soavt. [Glaukoma]. Glaukoma Nacional’noe rukovodstvo M.: GJeOTAR — Media, 2013. (in Russ.).
2. Nesterov A. P. [Glaukoma]. Glaukoma. Медицинское информационное агентство 2008, 355 p. (in Russ.).
3. Avetisov S. Je., Egorov E. A., Moshetova L. K. i soavt. [Ophthalmology]. Oftal’mologija: Nacional’noe rukovodstvo M.: GJeOTAR — Med, 2008. (in Russ.).
4. Alekseev I. B., Moshetova L. K., Vorob’eva I. V. [Medicamentous activation of uveoscleralе outflow at patients with the glaucoma proceeding on diabetes].Medikamentoznaja aktivacija uveoskleral’nogo ottoka u pacientov s glaukomoj, protekajushhej na fone saharnogo diabeta. Glaukoma [Glaukoma]. 2002; 1: 15‑17. (in Russ.).
5. Dujun I. A., Apaguni A. Je., Kamfarina I. A. [About Azopt’s efficiency at patients with primary open-angle glaucoma and diabetes.] Ob jeffektivnosti Azopta u pacientov s pervichnoj otkrytougol’noj glaukomoj i saharnym diabetom. Klinicheskaja oftal’mologija. Prilozh. k RMZh. [Clinical ophthalmology.] App. to RMJ 2011; 1: 19‑21. (in Russ.).
6. Kurysheva N. I. [Role of visualization methods of an optic’ s disk nerve and layer of a retina’ s nervous fibers in early glaucoma’ s diagnostics]. Rol’ metodov vizualizacii diska zritel’nogo nerva i sloja nervnyh volokon setchatki v rannej diagnostike glaukomy Glaucoma. [Glaucoma]. 2007; 1:16‑22. (in Russ.).
7. Borzunov O. I. Korotkih S. A., Kublanov V. S., V. V. Andreeva [Method of the combined treatment’s of open-angle glaucoma after laser hypotensive operation]. Sposob kombinirovannogo lechenija otkrytougol’noj glaukomy posle lazernoj gipotenzivnoj operacii. Patent RU [Patent RU] 2479290, 20.04.13. (in Russ.).
8. Korotkih S. A., Borzunov O. I. [Clinical assessment selective laser trabeculoplasty in combination with neuroprotective therapy at patients with open-angle glaucoma]. Klinicheskaja ocenka selektivnoj lazernoj trabekuloplastiki v sochetanii s nejroprotektornoj terapiej u pacientov s otkrytougol’noj glaukomoj. Ural’skij medicinskij zhurnal [Ural medical jornal] 2010; 10 (75): 131‑133. (in Russ.).
9. Borzunov O. I., Korotkih S. A., Zalesova V. V. [Features selective laser trabeculoplasty at patients with open-angle glaucoma in the conditions of a specialized hospital]. Osobennosti selektivnoj lazernoj trabekuloplastiki (slt) u pacientov s otkrytougol’noj glaukomoj v uslovijah specializirovannogo stacionara. Vestnik ural’skoj medicinskoj akademicheskoj nauki. Bulletin of the Ural medical academic of science 2011; 2 (34):77‑79. (in Russ.).
10. Borzunov O. I. [Optimization of the combined patient’s treatment with open-angle glaucoma]. Optimizacija kombinirovannogo lechenija pacientov s otkrytougol’noj glaukomoj. Dis. kand. med. nauk. Moskva, [Dis. kand. med. nauk Moscow 2012. (in Russ.).
11. Kublanov B. C. [Electrophysical method correction of disorders regulation’ s system brain’s blood supply]. Biomedicinskaja radiojelektronika [Biomedical radio electronics] 1999; 4:12‑15. (in Russ.).
12. Klamann M. K., Maier A. K., Gonnermann J. Adverse Effects and Short-term Results After Selective Laser Trabeculoplasty. Journal Of Glaucoma 2014; 23 (2), 105‑108.
13. Ha JH, Bowling B, Chen SD Cystoid macular oedema following selective laser trabeculoplasty in a diabetic patient. Clin Experiment Ophthalmol. 2013; 22: 121‑126.
14. Kurysheva N. I., Caregorodceva M. A., Rjabova T. Ja., Shlapak V. N. [Perfusion pressure and primary vascular disregulation at patients with glaucoma of normal pressure]. Perfuzionnoe davlenie i pervichnaja sosudistaja disreguljacija u bol’nyh glaukomoj normal’nogo davlenija. Klinicheskaja oftal’mologija RMZh. [Clinical ophthalmology] 2011; 1: 9‑12 (in Russ.).
15. Бакшинский П. П., Боголюбская А. Ю., Дроздова Г. А. [Vayvlet analysis of the general and eye microhaemo dynamics at patients with primary open-angle glaucoma with the normalized intraocular pressure]. Vajvlet analiz obshhej i glaznoj mikrogemodinamiki u bol’nyh pervichnoj otkrytougol’noj glaukomoj s normalizovannym vnutriglaznym davleniem. Glaukoma [Glaucoma] 2006; 1: 7‑15 (in Russ.).
Review
For citations:
Borzunov O.I., Features of ophthalmoneuroprotection in patients with open-angle glaucoma in combination with diabetic retinopathy. Ophthalmology in Russia. 2014;11(1):66-72. (In Russ.) https://doi.org/10.18008/1816-5095-2014-1-66-72
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