Retinal vessels caliber assessment in patients with arterial hypertension
https://doi.org/10.18008/1816-5095-2012-1-58-62
Abstract
Purpose: to evaluate the diagnostic capability of automated retinal vessels (RV) caliber estimation for hypertensive angiopathy.
Methods: this study included 146 patients (292 eyes) with arterial hypertension. All the subjects underwent fundus photography and RV caliber estimation. the latter was performed using newly developed computer-based method for automated vessel detection and central retinal arteriolar and venular equivalents determination (CRAE & CRVE). Sensitivity, specificity, and reproducibility of the method were estimated.
Results: the method of RV caliber assessment showed good reproducibility. the overall specificity and sensitivity were 74% and 80.77%, respectively. Computer-based method of retinal vascular caliber assessment revealed higher predictive value comparing with ophthalmoscopic assessment (AUC = 0.903 and 0.85, respectively). Retinal arteriolar and venular caliber and AVR tend to decrease with age. Higher blood pressure is associated with narrower retinal arterioles.
Conclusion: Novel method of RV caliber estimation demonstrated high information value. these findings are in good agreement
with data from major population-based studies.
About the Authors
N. S. Semenova
ГУНУ Факультет фундаментальной медицины МГУ им. М.В. Ломоносова, Москва
ФГБУ «Объединенная больница с поликлиникой» УД Президента РФ, Москва
Russian Federation
Russian Federation
V. S. Akopyan
ГУНУ Факультет фундаментальной медицины МГУ им. М.В. Ломоносова, Москва
ФГБУ «Объединенная больница с поликлиникой» УД Президента РФ, Москва
Russian Federation
Russian Federation
I. V. Filonenko
ГУНУ Факультет фундаментальной медицины МГУ им. М.В. Ломоносова, Москва
ФГБУ «Объединенная больница с поликлиникой» УД Президента РФ, Москва
Russian Federation
Russian Federation
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Review
For citations:
Semenova N.S., Akopyan V.S., Filonenko I.V. Retinal vessels caliber assessment in patients with arterial hypertension. Ophthalmology in Russia. 2012;9(1):58-62. (In Russ.) https://doi.org/10.18008/1816-5095-2012-1-58-62
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