Preview

Ophthalmology in Russia

Advanced search

Ultrasound Biomicroscopy Eye Anterior Segment in the Diagnosis of Senile Scleral Plaques. Clinical Case

https://doi.org/10.18008/1816-5095-2025-1-215-218

Abstract

Senile scleral plaque (SSP) is a degenerative disease of the sclera, characterized by the appearance of gray spots with well-defined borders located anterior to the horizontal rectus muscles. Hyaline degeneration of the sclera was first described by J.H. Parsons in 1904. Currently, it is believed that the primary cause of SSP formation is collagen degradation, reduced elastin content, and the deposition of calcium and lipids. This condition closely resembles sclerochoroidal calcification (SCC); however, SSP is localized in the anterior eye segment and is associated with the risk of complications that could threaten visual function or lead to eye loss. SSP appears as a gray spot with distinct irregular borders located anterior to the horizontal rectus muscles. On optical coherence tomography (OCT), it presents as an intrascleral cavity with hyporeflective contents and clear borders defined by unaltered scleral fibers. This article describes a clinical case of bilateral symmetrical eye involvement. During ultrasound biomicroscopy of the anterior segment in the area of interest, a localized scleral defect was visualized, above which a hyperechoic linear thickening of the coats was detected.

About the Authors

A. S. Stoyukhina
M.M. Krasnov Research Institute of Eye Diseases; Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Stoyukhina Alevtina S., MD, Leading Research Officer of Retinal and Optic Nerve Pathology Department, Professor of the Ophthalmology Department

Rossolimo str., 11A, B, Moscow, 119021

Trubetskaya str., 8, bld. 2, Moscow, 119048



D. V. Andzhelova
M.M. Krasnov Research Institute of Eye Diseases
Russian Federation

Andzhelova Diana V., MD, Leading Research Officer of Retinal and Optic Nerve Pathology Department

Rossolimo str., 11A, B, Moscow, 119021



O. V. Eksarenko
M.M. Krasnov Research Institute of Eye Diseases
Russian Federation

Eksarenko Olesya V., PhD, Research Officer of Retinal and Optic Nerve Pathology Department

Rossolimo str., 11A, B, Moscow, 119021



References

1. Scroggs MW, Klintworth GK. Senile scleral plaques: A histopathologic study using energy-dispersive X-ray microanalysis. Hum Pathol. 1991;22(6):557–562. doi: 10.1016/0046-8177(91)90232-E.

2. Roper K. Senile hyaline scleral plaques. Arch Ophthalmol. 1945;34(4):283–291. doi: 10.1001/archopht.1945.00890190283003.

3. Horowitz S, Damasceno N, Damasceno E. Prevalence and factors associated with scleral hyaline plaque: Clinical study of older adults in southeastern Brazil. Clin Ophthalmol. 2015;9:1187–1193. doi: 10.2147/OPTH.S82421.

4. Beck M, Schlatter B, Wolf S, Zinkernagel MS. Senile scleral plaques imaged with enhanced depth optical coherence tomography. Acta Ophthalmol. 2015;93(3):e188–e192. doi: 10.1111/aos.12547.

5. Svetozarskiy SN, Andreev AN. Capabilities of optical coherence tomography in examination of senile scleral plaques. Annals of Ophthalmology 2022;138(3):31–40 (In Russ.). doi: 10.17116/oftalma202213803129.

6. Cogan D, Kuwabara T. Focal Senile Translucency of the Sclera. Arch Ophthalmol. 1959;62(4):604–610. doi: 10.1001/archopht.1959.04220040066009.

7. Dreyer S, Rodriguez L, Worswick S. Scleral Plaques in Nephrogenic Systemic Fibrosis. Cutis. 2022;109(1):E31–E32. doi: 10.12788/cutis.0458.

8. Sivalingam A, Shields CL, Shields JA, McNamara JA, Jampol LM, Wood WJ, Daubert G. Idiopathic sclerochoroidal calcification. Ophthalmology. 1991;98(5):720–724. doi: 10.1016/s0161-6420(91)32228-0.

9. Honavar SG, Shields CL, Demirci H, Shields JA. Sclerochoroidal calcification: clinical manifestations and systemic associations. Arch Ophthalmol. 2001;119(6):833–840. doi: 10.1001/archopht.119.6.833.

10. Manschot WA. Senile scleral plaques and senile scleromalacia. Br J Ophthalmol. 1978;62(6):376–380. doi: 10.1136/BJO.62.6.376.

11. Donoso L, Shields J, Nagy R. Epibulbar lesions simulating extraocular extension of uveal melanomas. Ann Ophthalmol. 1982;14(12):1120–1123.


Review

For citations:


Stoyukhina A.S., Andzhelova D.V., Eksarenko O.V. Ultrasound Biomicroscopy Eye Anterior Segment in the Diagnosis of Senile Scleral Plaques. Clinical Case. Ophthalmology in Russia. 2025;22(1):215-218. (In Russ.) https://doi.org/10.18008/1816-5095-2025-1-215-218

Views: 134


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1816-5095 (Print)
ISSN 2500-0845 (Online)